Zobrazeno 1 - 10
of 202
pro vyhledávání: '"caspase 4"'
Autor:
Lalitha Tanjore Arunachalam, Snophia Suresh, Vamsi Lavu, Shankarram Vedamanickam, John Ebinezer, Bhavishya Balachandran
Publikováno v:
Journal of Indian Society of Periodontology, Vol 28, Iss 3, Pp 297-303 (2024)
Background: Periodontitis and diabetes are chronic diseases where inflammation plays a central role, with each condition exacerbating the other. Pyroptosis, an inflammatory form of programmed cell death, is implicated in periodontitis and diabetes. T
Externí odkaz:
https://doaj.org/article/665585e3d67a4a63ae8b29a39458a9c2
Autor:
Ying Zhou, Mei Yang, Rishun Fu, Weihuang Liu, Zihan Cai, Hanyu Lin, Siheng Li, Chuanyu Zong, Yun Chen, Zan Tong
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The combination of anti-angiogenic treatment and immunotherapy presents a promising strategy against colon cancer. Interleukin-17F (IL-17F) emerges as a critical immune cell cytokine expressed in colonic epithelial cells, demonstrating poten
Externí odkaz:
https://doaj.org/article/45bf06501292412f919cfab36496975d
Autor:
Yoshihiro Shidoji
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 7, Pp 100396- (2023)
Geranylgeranoic acid (GGA) was first reported in 1983 as one of the mevalonic acid metabolites, but its biological significance was not studied for a long time. Our research on the antitumor effects of retinoids led us to GGA, one of the acyclic reti
Externí odkaz:
https://doaj.org/article/ab69704004b142aca4bd85fd10827b86
Akademický článek
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Autor:
Ljubomir Vitkov, Luis E. Muñoz, Janina Schoen, Jasmin Knopf, Christine Schauer, Bernd Minnich, Martin Herrmann, Matthias Hannig
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The subgingival biofilm attached to tooth surfaces triggers and maintains periodontitis. Previously, late-onset periodontitis has been considered a consequence of dysbiosis and a resultant polymicrobial disruption of host homeostasis. However, a mult
Externí odkaz:
https://doaj.org/article/09f6f2d40de245ad84d0c676a891723a
Autor:
Zsofi Digby, Panagiotis Tourlomousis, James Rooney, Joseph P. Boyle, Betsaida Bibo-Verdugo, Robert J. Pickering, Steven J. Webster, Thomas P. Monie, Lee J. Hopkins, Nobuhiko Kayagaki, Guy S. Salvesen, Soren Warming, Lucy Weinert, Clare E. Bryant
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109614- (2021)
Summary: Zoonotic pathogens, such as COVID-19, reside in animal hosts before jumping species to infect humans. The Carnivora, like mink, carry many zoonoses, yet how diversity in host immune genes across species affect pathogen carriage is poorly und
Externí odkaz:
https://doaj.org/article/bb9d22033809476d95fc1b138b38dc56
Autor:
Lingfeng Meng, Zijian Tian, Xingbo Long, Tongxiang Diao, Maolin Hu, Miao Wang, Wei Zhang, Yaoguang Zhang, Jianye Wang, Yuhui He
Publikováno v:
Frontiers in Genetics, Vol 11 (2021)
The dysregulation of caspase 4 (CASP4) expression is related to the occurrence, development, and outcome of many malignant tumors; however, its role in clear cell renal cell carcinoma (ccRCC) remains unclear. Herein, we investigated the expression of
Externí odkaz:
https://doaj.org/article/0f8b3e7ec93a45d98e245fbc406a33c2
Akademický článek
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Akademický článek
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Publikováno v:
PeerJ, Vol 7, p e7321 (2019)
Key factors of pyroptosis play an important role in the inflammatory response to connective tissue disease (CTD). However, information on active and stable stages of CTD is scarce. To distinguish the differences of concentrations of C-reactive protei
Externí odkaz:
https://doaj.org/article/d4418db907184215828d400ebdc73a75