Zobrazeno 1 - 10
of 1 072
pro vyhledávání: '"cas12a"'
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Due to limitations in conventional disease vector control strategies including the rise of insecticide resistance in natural populations of mosquitoes, genetic control strategies using CRISPR gene drive systems have been under serious consid
Externí odkaz:
https://doaj.org/article/83d9ac40bb234251b5065e133f5694e3
Autor:
Jing Li, Qi Wei, Yiqiu Cheng, Dali Kong, Zhe Kong, Yongping Ke, Xiaofei Dang, Jian-Kang Zhu, Hiroaki Shimada, Daisuke Miki
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Gene targeting (GT) allows precise manipulation of genome sequences, such as knock-ins and sequence substitutions, but GT in seed plants remains a challenging task. Engineered sequence-specific nucleases (SSNs) are known to facilitate GT via
Externí odkaz:
https://doaj.org/article/8c0974def0714887ac55cd3bc5207f01
Autor:
Baicheng Huang, Ling Guo, Hang Yin, Yue Wu, Zihan Zeng, Sujie Xu, Yufeng Lou, Zhimin Ai, Weiqiang Zhang, Xingchi Kan, Qian Yu, Shimin Du, Chao Li, Lina Wu, Xingxu Huang, Shengqi Wang, Xinjie Wang
Publikováno v:
iMeta, Vol 3, Iss 4, Pp n/a-n/a (2024)
Abstract Rapid and accurate diagnostic tests are fundamental for improving patient outcomes and combating infectious diseases. The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Cas12a‐based detection system has emerged as a pro
Externí odkaz:
https://doaj.org/article/1edb7301e13e47d480f27da58ea48d87
Akademický článek
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Autor:
Meiying Tan, Lina Liang, Chuan Liao, Zihan Zhou, Shaoping Long, Xueli Yi, Chunfang Wang, Caiheng Wei, Jinyuan Cai, Xuebin Li, Guijiang Wei
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The bacterium Klebsiella pneumoniae (Kp) was the primary pathogen of hospital-acquired infection, but the current detection method could not rapidly and conveniently identify Kp. Recombinase polymerase amplification (RPA) was a fast and convenient is
Externí odkaz:
https://doaj.org/article/9ea31dec999a43fb9f299560f9ca502a
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 36, Iss 11, Pp 677-681 (2023)
CRISPR-Cas editing systems have proved to be powerful tools for functional genomics research, but their effectiveness in many non-model species remains limited. In the potato and tomato pathogen Phytophthora infestans, an editing system was previousl
Externí odkaz:
https://doaj.org/article/7eb3c55c2706403fa91e88889482bc16
Autor:
Hongge Jia, Ahmad A. Omar, Jin Xu, Javier Dalmendray, Yuanchun Wang, Yu Feng, Wenting Wang, Zhuyuan Hu, Jude W. Grosser, Nian Wang
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Citrus canker disease affects citrus production. This disease is caused by Xanthomonas citri subsp. citri (Xcc). Previous studies confirmed that during Xcc infection, PthA4, a transcriptional activator like effector (TALE), is translocated from the p
Externí odkaz:
https://doaj.org/article/ff19c95d566b43b195a1bbf08368edf6
Autor:
Songkuan Zhuang, Tianshuai Hu, Hongzhong Zhou, Shiping He, Jie Li, Yuehui Zhang, Dayong Gu, Yong Xu, Yijian Chen, Jin Wang
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Studies have indicated that the intracellular nicotinamide adenine dinucleotide (NAD+) level is associated with the occurrence and development of many diseases. However, traditional nicotinamide adenine dinucleotide (NAD+) detection techniques are ti
Externí odkaz:
https://doaj.org/article/4efe6cfbeab441aba20c3c19ce5aa154
Autor:
Huanhuan Wang, Jing Liang, Like Chen, Bufang Deng, Dongfang Gu, Xiaoshuang Liu, Shan Jin, Rongfang Xu, Ruiying Qin, Yitong Zhu, Liangxia Zhao, Dourong Kou, Yanjun Chen, Yingli Jiang, Juan Li, Pengcheng Wei
Publikováno v:
Crop Journal, Vol 11, Iss 5, Pp 1451-1457 (2023)
Base editors of the Cas9 system have been widely used for precise nucleotide substitution in crops. In this study, Cas12a was applied to construct plant cytosine base editors (CBEs). The main elements of Cas12a-CBEs were engineered and their efficien
Externí odkaz:
https://doaj.org/article/724c37f7920e44d29854df4c1f7469aa
Autor:
Yan Zhang, Yufei Lyu, Dongshu Wang, Meijie Feng, Sicheng Shen, Li Zhu, Chao Pan, Xiaodong Zai, Shuyi Wang, Yan Guo, Shujuan Yu, Xiaowei Gong, Qiwei Chen, Hengliang Wang, Yuanzhi Wang, Xiankai Liu
Publikováno v:
Microorganisms, Vol 12, Iss 5, p 1018 (2024)
Human brucellosis caused by Brucella is a widespread zoonosis that is prevalent in many countries globally. The high homology between members of the Brucella genus and Ochrobactrum spp. often complicates the determination of disease etiology in patie
Externí odkaz:
https://doaj.org/article/2c29207d3908412d9b48b0d1c765347e