Zobrazeno 1 - 10
of 205
pro vyhledávání: '"cardiac reprogramming"'
Autor:
Juntao Fang, Qiangbing Yang, Renée G. C. Maas, Michele Buono, Bram Meijlink, Dyonne Lotgerink Bruinenberg, Ernest Diez Benavente, Michal Mokry, Alain van Mil, Li Qian, Marie-José Goumans, Raymond Schiffelers, Zhiyong Lei, Joost P. G. Sluijter
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background After myocardial infarction, the lost myocardium is replaced by fibrotic tissue, eventually progressively leading to myocardial dysfunction. Direct reprogramming of fibroblasts into cardiomyocytes via the forced overexpression of
Externí odkaz:
https://doaj.org/article/e3965e3745d94f5a8c07effa85a5711d
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 11, Iss 9, p 273 (2024)
Heart disease continues to be one of the most fatal conditions worldwide. This is in part due to the maladaptive remodeling process by which ischemic cardiac tissue is replaced with a fibrotic scar. Direct cardiac reprogramming presents a unique solu
Externí odkaz:
https://doaj.org/article/182e6e01f5274c9e944e530f9b04a4c9
Akademický článek
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Autor:
Hiroyuki Yamakawa, Masaki Ieda
Publikováno v:
Inflammation and Regeneration, Vol 41, Iss 1, Pp 1-10 (2021)
Abstract Japan faces an increasing incidence of heart disease, owing to a shift towards a westernized lifestyle and an aging demographic. In cases where conventional interventions are not appropriate, regenerative medicine offers a promising therapeu
Externí odkaz:
https://doaj.org/article/9351bf92925c46a4a4a16533519f963d
Autor:
Siyuan Ma, Junyu Yan, Lu Chen, Yingqi Zhu, Kaitong Chen, Cankun Zheng, Mengjia Shen, Yulin Liao
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Recent research has suggested that cardiac regeneration may have the widely applicable potential of treating heart failure (HF). A comprehensive understanding of the development status of this field is conducive to its development. Howeve
Externí odkaz:
https://doaj.org/article/783d7a0782bd42c388a50a09367cbf6d
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102365- (2021)
Cardiovascular disease, until now, is still the leading cause of death in the United States. Due to the limited regenerative capacity of adult hearts, the damage caused by heart injury cannot be reversed and eventually progress into heart failure. In
Externí odkaz:
https://doaj.org/article/684e38437a054f62b735d17e3d6c583b
Autor:
Hong Zhao, Yi Zhang, Xiaochan Xu, Qiushi Sun, Chunyan Yang, Hao Wang, Junbo Yang, Yang Yang, Xiaochun Yang, Yi Liu, Yang Zhao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Direct conversion of fibroblasts into induced cardiomyocytes (iCMs) holds promising potential to generate functional cardiomyocytes for drug development and clinical applications, especially for direct in situ heart regeneration by delivery of reprog
Externí odkaz:
https://doaj.org/article/b620399cd49a44f2a11dc0e163798917
Autor:
Andrew S. Riching, Kunhua Song
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2021)
Ischemic heart disease is the leading cause of morbidity and mortality in the world. While pharmacological and surgical interventions developed in the late twentieth century drastically improved patient outcomes, mortality rates over the last two dec
Externí odkaz:
https://doaj.org/article/3e6ed218283e4aae8e329f311479839a
Autor:
Emilia Pascale, Carmen Caiazza, Martina Paladino, Silvia Parisi, Fabiana Passaro, Massimiliano Caiazzo
Publikováno v:
Cells, Vol 11, Iss 6, p 940 (2022)
Cell reprogramming is a groundbreaking technology that, in few decades, generated a new paradigm in biomedical science. To date we can use cell reprogramming to potentially generate every cell type by converting somatic cells and suitably modulating
Externí odkaz:
https://doaj.org/article/c18fe1a8a884436ca798b392ab8d4549