Zobrazeno 1 - 10
of 3 826
pro vyhledávání: '"cardiac fibroblasts"'
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 10605-10621 (2024)
Yijuan Feng,1,* Yan Wang,1,* Li Li,1,* Yan Yang,1 Xiaoqiu Tan,1– 3 Tangting Chen1,2 1Key Laboratory of Medical Electrophysiology of the Ministry of Education, Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of
Externí odkaz:
https://doaj.org/article/81f6743d1ef34071a5c2fed9231a80ed
Autor:
Shujun Yang, Liying Pei, Zijie Huang, Yinsheng Zhong, Jun Li, Yinghui Hong, Huibao Long, Xuxiang Chen, Changqing Zhou, Guanghui Zheng, Chaotao Zeng, Haidong Wu, Tong Wang
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Background Myocardial infarction (MI) leads to enhanced activity of cardiac fibroblasts (CFs) and abnormal deposition of extracellular matrix proteins, resulting in cardiac fibrosis. Tartrate-resistant acid phosphatase 5 (ACP5) has been show
Externí odkaz:
https://doaj.org/article/242d850a424a4905b2a9e4ba2957e691
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background Cardiac fibroblasts (CFs) are activated after initial injury, and then differentiate into myofibroblasts (MFs), which play a pivotal role as the primary mediator cells in pathological remodeling. Sodium butyrate (NaB), being a met
Externí odkaz:
https://doaj.org/article/094c8a546b354fb6a6e2e361ff4eb423
Publikováno v:
All Life, Vol 17, Iss 1 (2024)
Cardiac fibroblasts (CFs) are of vital importance for post-myocardial infarction (MI) remodeling. This study explored the role of Placenta specific 8 (Plac8) in MI on the basis of single-cell RNA-Seq (scRNA-Seq) data (GSE136088) and micro-array data
Externí odkaz:
https://doaj.org/article/3696d0e81f7b4f319961c3b68ae90c5b
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35219- (2024)
Diabetic cardiomyopathy (DCM) is a common complication of diabetes, and its pathogenesis remains elusive. Ferroptosis, a process dependent on iron-mediated cell death, plays a crucial role in DCM via disrupted iron metabolism, lipid peroxidation, and
Externí odkaz:
https://doaj.org/article/07ccc63d0f2d468fa59635f1032ceab0
Autor:
Te-An Chen, Brandon B. Zhao, Richard A. Balbin, Sameeksha Sharma, Donggi Ha, Timothy J. Kamp, Yuxiao Zhou, Feng Zhao
Publikováno v:
Matrix Biology Plus, Vol 23, Iss , Pp 100151- (2024)
Extracellular matrix (ECM) fabricated using human induced pluripotent stem cells (hiPSCs)-derived cardiac fibroblasts (hiPSC-CFs) could serve as a completely biological scaffold for an engineered cardiac patch, leveraging the unlimited source and out
Externí odkaz:
https://doaj.org/article/bb95a99955464065987e6c3d37bacac7
Autor:
Marta Delgado-Arija, Patricia Genovés, Lorena Pérez-Carrillo, Irene González-Torrent, Isaac Giménez-Escamilla, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón, Esther Roselló-Lletí
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Cardiac fibroblast activation protein (FAP) has an emerging role in heart failure (HF). A paradoxical reduction in its levels in pathological conditions associated with acute processes has been observed. We aimed to identify FAP c
Externí odkaz:
https://doaj.org/article/7f007be5ed3a4a35954fc3151842bf82
Decellularized heart extracellular matrix alleviates activation of hiPSC-derived cardiac fibroblasts
Autor:
Charles M. Kerr, Sophia E. Silver, Yi Sun Choi, Martha E. Floy, Amy D. Bradshaw, Seung-Woo Cho, Sean P. Palecek, Ying Mei
Publikováno v:
Bioactive Materials, Vol 31, Iss , Pp 463-474 (2024)
Human induced pluripotent stem cell derived cardiac fibroblasts (hiPSC-CFs) play a critical role in modeling human cardiovascular diseases in vitro. However, current culture substrates used for hiPSC-CF differentiation and expansion, such as Matrigel
Externí odkaz:
https://doaj.org/article/085242f56f0e407293727c5ae5c5b1f0
Publikováno v:
Health Science Reports, Vol 7, Iss 4, Pp n/a-n/a (2024)
Abstract Background and Aims Fibrotic tissue formed after myocardial infarction (MI) can be as detrimental as MI itself. However, current in vitro cardiac fibrosis models fail to recapitulate the complexities of post‐MI tissue. Moreover, although M
Externí odkaz:
https://doaj.org/article/7f7295325d194ac7b3a688044a403904
Publikováno v:
Physiological Reports, Vol 12, Iss 6, Pp n/a-n/a (2024)
Abstract Cardiac fibroblasts (CFs) are an attractive target for reducing pathological cardiac remodeling, and understanding the underlying mechanisms of these processes is the key to develop successful therapies for treating the pressure‐overloaded
Externí odkaz:
https://doaj.org/article/cba148bde38f493782151afd489ec03e