Zobrazeno 1 - 10
of 5 923
pro vyhledávání: '"carcinoma cell"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Nasopharyngeal carcinoma (NPC) is one of the common malignant tumors, and its pathogenesis has not been fully clarified. This study aims to explore the impact of RNA interference on the growth and invasion of NPC cells. Asparaginase and isoa
Externí odkaz:
https://doaj.org/article/287c6a7370774b5eae31c8173f1a6f11
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-25 (2024)
Abstract A recent scientific investigation has shown promising results of selenium nanoparticles (SeNPs) for the anticancer and antimicrobial activities. This study aims to evaluate the effects of PVP SeNPs on bacterial strains, including Staphylococ
Externí odkaz:
https://doaj.org/article/70d1eb5d2efa4b858b097e64a17178d4
Autor:
Maria Georgiadou, George Notas, Ioannis Tsomidis, Argyro Voumbouraki, Ioannis Drygiannakis, George Emmanouil, Elias Kouroumalis
Publikováno v:
Gastroenterology Insights, Vol 15, Iss 3, Pp 614-631 (2024)
The anti-tumoral activity of somatostatin has been demonstrated in both animal experiments and human tumors. Clinical trials have reported conflicting results. We therefore hypothesized that somatostatin might have different effects in various hepato
Externí odkaz:
https://doaj.org/article/2d9b837cf3594f3987a22456e3af7c6c
Autor:
Yuan-yuan Lu, Yi Li, Zhi-li Chen, Xiang-hua Xiong, Qing-yang Wang, Hao-long Dong, Chen Zhu, Jia-zhen Cui, Ao Hu, Lei Wang, Na Song, Gang Liu, Hui-peng Chen
Publikováno v:
Molecular and Cellular Probes, Vol 77, Iss , Pp 101981- (2024)
The clinical treatment of hepatocellular carcinoma (HCC) is still a heavy burden worldwide. Intracellular microRNAs (miRNAs) commonly express abnormally in cancers, thus they are potential therapeutic targets for cancer treatment. miR-21 is upregulat
Externí odkaz:
https://doaj.org/article/c6d4e820ff6949e2ab4dff7f827be63c
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31106- (2024)
Background: Poria acid (PAC) is a triterpene compound found in Poria cocos, a traditional Chinese medicine (TCM). The current study aims to explore the therapeutic effects and potential mechanisms of PAC on the migration and proliferation of human re
Externí odkaz:
https://doaj.org/article/6a9d9c230db14d4ca768ecece039a08d
Autor:
Alina S. Nazarenko, Yulia K. Biryukova, Ekaterina O. Orlova, Kirill N. Trachuk, Alla L. Ivanova, Alla V. Belyakova, Nikolai B. Pestov, Mikhail F. Vorovitch, Aydar A. Ishmukhametov, Nadezhda M. Kolyasnikova
Publikováno v:
Вопросы вирусологии, Vol 68, Iss 6, Pp 536-548 (2023)
Introduction. Flaviviruses, possessing natural neurotropicity could be used in glioblastoma therapy using attenuated strains or as a delivery system for antitumor agents in an inactivated form. Objective. To investigate the sensitivity of glioblas
Externí odkaz:
https://doaj.org/article/e4def4e6cbf1471bbc5241c08ec63f0d
Autor:
Young Sun Hwang
Publikováno v:
치위생과학회지, Vol 23, Iss 3, Pp 216-224 (2023)
Background: Smilax glabra has various pharmacological activities and is widely used as a herbal medicine. Although the incidence of oral cancer is low, the recurrence rate is high, and the 5-year survival rate is poor. It is necessary to search for a
Externí odkaz:
https://doaj.org/article/fb15274f1a5e44e89f91e66e649b63b3
Autor:
Mohammed Zuhair Al-Hayali, Choy-Eng Nge, Kuan Hon Lim, Hilary M. Collins, Toh-Seok Kam, Tracey D. Bradshaw
Publikováno v:
Molecules, Vol 29, Iss 11, p 2654 (2024)
Natural products contribute substantially to anticancer therapy; the plant kingdom provides an important source of molecules. Conofolidine is a novel Aspidosperma-Aspidosperma bisindole alkaloid isolated from the Malayan plant Tabernaemontana corymbo
Externí odkaz:
https://doaj.org/article/d5b3d51d6b3d4a9195e365bb4d7c2698
Autor:
Xia Lin, Qingyuan Yi, Binyang Qing, Weisen Lan, Fangcheng Jiang, Zefeng Lai, Jijun Huang, Qing Liu, Jimin Jiang, Mian Wang, Lianjia Zou, Xinbi Huang, Jianyi Wang
Publikováno v:
Molecules, Vol 29, Iss 9, p 1961 (2024)
In this study, two “on–off” probes (BF2-cur-Ben and BF2-cur-But) recognizing acetylcholinesterase (AChE) were designed and synthesized. The obtained probes can achieve recognition of AChE with good selectivity and pH-independence with a linear
Externí odkaz:
https://doaj.org/article/8198bbe8ab53477c8b3e151f75511b01
Publikováno v:
Molecules, Vol 29, Iss 8, p 1779 (2024)
We introduced a terminal alkyne into the core structure of dolutegravir, resulting in the synthesis of 34 novel dolutegravir-1,2,3-triazole compounds through click chemistry. These compounds exhibited remarkable inhibitory activities against two hepa
Externí odkaz:
https://doaj.org/article/6ed4ca75a6ee4c5cbaabc879b27756ad