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Comprehensive Literature Review of Hyperpolarized Carbon-13 MRI: The Road to Clinical Application

Autor: Michael Vaeggemose, Rolf F. Schulte, Christoffer Laustsen

Publikováno v: Metabolites, Vol 11, Iss 4, p 219 (2021)

This review provides a comprehensive assessment of the development of hyperpolarized (HP) carbon-13 metabolic MRI from the early days to the present with a focus on clinical applications. The status and upcoming challenges of translating HP carbon-13

Externí odkaz: https://doaj.org/article/a1d6fbb1985048cb842f8023c2029ce5

Combined 23 Na and 13 C imaging at 3.0 Tesla using a single-tuned large FOV birdcage coil

Autor: Kaggie, Joshua D, Lanz, Titus, McLean, Mary A, Riemer, Frank, Schulte, Rolf F, Benjamin, Arnold JV, Kessler, Dimitri A, Sun, Chang, Gilbert, Fiona J, Graves, Martin J, Gallagher, Ferdia A

PURPOSE: An unmet need in carbon-13 (13 C)-MRI is a transmit system that provides uniform excitation across a large FOV and can accommodate patients of wide-ranging body habitus. Due to the small difference between the resonant frequencies, sodium-23

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______109::0aa4fe27094966fa63d836ad5da65d87
https://www.repository.cam.ac.uk/handle/1810/318195

Hyperpolarized Carbon-13 MRI for Early Response Assessment of Neoadjuvant Chemotherapy in Breast Cancer Patients

Autor: Suet-Feung Chin, Bruno Carmo, Jean Abraham, Andrew J. Patterson, Brian H. White, Amy Schiller, Ashley Grimmer, Kevin M. Brindle, Raquel Manzano Garcia, Andrew B. Gill, Joshua D. Kaggie, Rhys Slough, Gabrielle C Baxter, David Y. Lewis, Rolf F. Schulte, Arnold J. V. Benjamin, Johanna Field-Rayner, Justine Kane, Carlos Caldas, Elena Provenzano, Mary A. McLean, Matthew Locke, Ferdia A. Gallagher, Titus Lanz, Stephan Ursprung, Vasiliki Papalouka, Roslin Russell, Fiona J. Gilbert, Ramona Woitek, Lucian Beer, Martin J. Graves, Oscar M. Rueda, Ilse Patterson, Beth Latimer-Bowman, James Wason, Leonardo Rundo, Evis Sala, Andrew N. Priest, Amy Frary

Publikováno v: Cancer research

Hyperpolarized 13C-MRI is an emerging tool for probing tissue metabolism by measuring 13C-label exchange between intravenously injected hyperpolarized [1–13C]pyruvate and endogenous tissue lactate. Here, we demonstrate that hyperpolarized 13C-MRI c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc0b71bab642195ff9bcea0177b252f
https://pubmed.ncbi.nlm.nih.gov/34625424

Assessment of mouse liver [1-13C]pyruvate metabolism by dynamic hyperpolarized MRS

Autor: Ulrik Kræmer Sundekilde, Haiyun Qi, Christian Østergaard Mariager, Hans Stødkilde-Jørgensen, Jonas T. Treebak, Niels Jessen, Thomas Nielsen, Christoffer Laustsen, Kasper F. Høyer, Steffen Ringgaard

Publikováno v: Faarkrog Høyer, K, Laustsen, C, Ringgaard, S, Qi, H, Mariager, C Ø, Nielsen, T S, Sundekilde, U K, Treebak, J T, Jessen, N & Stødkilde-Jørgensen, H 2019, ' Assessment of mouse liver [1-13 C]pyruvate metabolism by dynamic hyperpolarized MRS ', Journal of Endocrinology, vol. 242, no. 3, pp. 251-260 . https://doi.org/10.1530/JOE-19-0159

Hyperpolarized [1-13C]pyruvate magnetic resonance (MR) spectroscopy has the unique ability to detect real-time metabolic changes in vivo owing to its high sensitivity compared with thermal MR and high specificity compared with other metabolic imaging

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba968c09f3654862655a592f0c682ec1
https://pubmed.ncbi.nlm.nih.gov/31311004