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Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress.

Autor: Korobkina ED; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Calejman CM; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Haley JA; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Kelly ME; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA., Li H; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Gaughan M; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Chen Q; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Pepper HL; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Ahmad H; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Boucher A; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Fluharty SM; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Lin TY; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Lotun A; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Peura J; Division of Hematology-Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Trefely S; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Green CR; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA., Vo P; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Semenkovich CF; Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, St. Louis, MO, USA., Pitarresi JR; Division of Hematology-Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Spinelli JB; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Aydemir O; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Metallo CM; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.; Molecular and Cellular Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA., Lynes MD; MaineHealth Institute for Research, Scarborough, ME, USA., Jang C; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA., Snyder NW; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Wellen KE; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Guertin DA; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA. david.guertin@umassmed.edu.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA. david.guertin@umassmed.edu.

Publikováno v: Nature metabolism [Nat Metab] 2024 Oct 14. Date of Electronic Publication: 2024 Oct 14.

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Considerations of Low Carbohydrate Availability (LCA) to Relative Energy Deficiency in Sport (RED-S) in Female Endurance Athletes: A Narrative Review

Autor: Melissa T. Lodge, Christie L. Ward-Ritacco, Kathleen J. Melanson

Publikováno v: Nutrients, Vol 15, Iss 20, p 4457 (2023)

The purpose of this narrative review is to identify health and performance consequences associated with LCA in female endurance athletes. The intake of carbohydrates (CHO) before, during, and after exercise has been demonstrated to support sport perf

Externí odkaz: https://doaj.org/article/44ce718b56be4551861ee9094d0489b5