Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.

Autor: Dubiez E; European Molecular Biology Laboratory, 71 Avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 9, France; Univ. Grenoble Alpes, CNRS, CEA, IBS, 38000 Grenoble, France., Pellegrini E; European Molecular Biology Laboratory, 71 Avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 9, France., Finderup Brask M; Department of Molecular Biology and Genetics, Universitetsbyen 81, Aarhus University, Aarhus, Denmark., Garland W; Department of Molecular Biology and Genetics, Universitetsbyen 81, Aarhus University, Aarhus, Denmark., Foucher AE; Univ. Grenoble Alpes, CNRS, CEA, IBS, 38000 Grenoble, France., Huard K; European Molecular Biology Laboratory, 71 Avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 9, France., Heick Jensen T; Department of Molecular Biology and Genetics, Universitetsbyen 81, Aarhus University, Aarhus, Denmark., Cusack S; European Molecular Biology Laboratory, 71 Avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 9, France. Electronic address: cusack@embl.fr., Kadlec J; Univ. Grenoble Alpes, CNRS, CEA, IBS, 38000 Grenoble, France. Electronic address: jan.kadlec@ibs.fr.

Publikováno v: Cell reports [Cell Rep] 2024 Jan 23; Vol. 43 (1), pp. 113639. Date of Electronic Publication: 2024 Jan 04.

Nonsense-mediated mRNA decay of mRNAs encoding a signal peptide occurs primarily after mRNA targeting to the endoplasmic reticulum.

Autor: Shin MK; Department of Life Sciences, Korea University, Seoul 02841, Republic of Korea., Chang J; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea., Park J; Department of Life Sciences, Korea University, Seoul 02841, Republic of Korea., Lee HJ; Department of Life Sciences, Korea University, Seoul 02841, Republic of Korea., Woo JS; Department of Life Sciences, Korea University, Seoul 02841, Republic of Korea., Kim YK; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.

Publikováno v: Molecules and cells [Mol Cells] 2024 Apr; Vol. 47 (4), pp. 100049. Date of Electronic Publication: 2024 Mar 20.

Identification and validation of N ⁷ -methylguanosine-associated gene NCBP1 as prognostic and immune-associated biomarkers in breast cancer patients.

Autor: Li J; Department of General Surgery Sciences, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/ Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, China., Zheng L; Department of Vascular Surgery, The Second Hospital of Shanxi Medical University, Taiyuan, China., Song L; Thyroid Surgery Department, First Hospital of Shanxi Medical University, Taiyuan, China., Dong Z; Gastroenterology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, China., Bai W; Department of General Surgery Sciences, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/ Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, China., Qi L; Department of Breast Surgery, National Cancer Center/National Cancer Clinical Medical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Publikováno v: Journal of cellular and molecular medicine [J Cell Mol Med] 2024 Jan; Vol. 28 (2), pp. e18067. Date of Electronic Publication: 2023 Dec 10.

NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models.

Autor: Singh MD; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America., Jensen M; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America., Lasser M; Department of Biology, Boston College, Chestnut Hill, Massachusetts, United States of America., Huber E; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America., Yusuff T; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America., Pizzo L; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America., Lifschutz B; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America., Desai I; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America., Kubina A; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America., Yennawar S; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America., Kim S; Department of Biology, Boston College, Chestnut Hill, Massachusetts, United States of America., Iyer J; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America., Rincon-Limas DE; Department of Neurology, McKnight Brain Institute, University of Florida, Gainesville, Florida, United States of America., Lowery LA; Department of Biology, Boston College, Chestnut Hill, Massachusetts, United States of America.; Department of Medicine, Boston University Medical Center, Boston, Massachusetts, United States of America., Girirajan S; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America.; Department of Anthropology, Pennsylvania State University, University Park, Pennsylvania, United States of America.

Publikováno v: PLoS genetics [PLoS Genet] 2020 Feb 13; Vol. 16 (2), pp. e1008590. Date of Electronic Publication: 2020 Feb 13 (Print Publication: 2020).

Simultaneous CRISPR/Cas9-mediated editing of cassava eIF4E isoforms nCBP-1 and nCBP-2 reduces cassava brown streak disease symptom severity and incidence.

Autor: Gomez MA; Department of Plant and Microbial Biology and Innovative Genomics Institute, University of California, Berkeley, CA, USA., Lin ZD; Donald Danforth Plant Science Center, St. Louis, MO, USA., Moll T; Donald Danforth Plant Science Center, St. Louis, MO, USA., Chauhan RD; Donald Danforth Plant Science Center, St. Louis, MO, USA., Hayden L; Donald Danforth Plant Science Center, St. Louis, MO, USA., Renninger K; Donald Danforth Plant Science Center, St. Louis, MO, USA., Beyene G; Donald Danforth Plant Science Center, St. Louis, MO, USA., Taylor NJ; Donald Danforth Plant Science Center, St. Louis, MO, USA., Carrington JC; Donald Danforth Plant Science Center, St. Louis, MO, USA., Staskawicz BJ; Department of Plant and Microbial Biology and Innovative Genomics Institute, University of California, Berkeley, CA, USA., Bart RS; Donald Danforth Plant Science Center, St. Louis, MO, USA.

Publikováno v: Plant biotechnology journal [Plant Biotechnol J] 2019 Feb; Vol. 17 (2), pp. 421-434. Date of Electronic Publication: 2018 Oct 05.