Zobrazeno 1 - 10
of 960
pro vyhledávání: '"cannabinoid receptor 1"'
Autor:
Rosalba Senese, Giuseppe Petito, Elena Silvestri, Maria Ventriglia, Nicola Mosca, Nicoletta Potenza, Aniello Russo, Sara Falvo, Francesco Manfrevola, Gilda Cobellis, Teresa Chioccarelli, Veronica Porreca, Vincenza Grazia Mele, Rosanna Chianese, Pieter de Lange, Giulia Ricci, Federica Cioffi, Antonia Lanni
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
IntroductionThe contribution of Cannabinoid type 1 receptor (CB1) in mitochondrial energy transduction mechanisms and mitochondrial activities awaits deeper investigations. Our study aims to assess the impact of CB1 absence on the mitochondrial compa
Externí odkaz:
https://doaj.org/article/6dbd6e5a7fe34a61938b8419aae3a7ab
Autor:
Tianxin Wang, Wenqin Tang, Ziyi Zhao, Ran Zhao, Zhenyu Lv, Xuzhen Guo, Quanchang Gu, Boxiang Liu, Haoyu Lv, Jiayan Chen, Kaiquan Zhang, Fahui Li, Jiangyun Wang
Publikováno v:
Advanced Science, Vol 11, Iss 14, Pp n/a-n/a (2024)
Abstract The G‐protein‐coupled human cannabinoid receptor 1 (CB1) is a promising therapeutic target for pain management, inflammation, obesity, and substance abuse disorders. The structures of CB1‐Gi complexes in synthetic agonist‐bound forms
Externí odkaz:
https://doaj.org/article/30365fbeb6904c4dad4d657e84dc1973
Autor:
Christina Sathyanathan Vijayaraghavan, Lakshmi Sundaram Raman, Shanmugapriya Surenderan, Harpreet Kaur, Mohanapriya Dandapani Chinambedu, Sadras Panchatcharam Thyagarajan, Mary Elizabeth Gnanambal Krishnan
Publikováno v:
Molecules, Vol 29, Iss 8, p 1737 (2024)
The cannabinoid-type I (CB1) receptor functions as a double-edged sword to decide cell fate: apoptosis/survival. Elevated CB1 receptor expression is shown to cause acute ceramide accumulation to meet the energy requirements of fast-growing cancers. H
Externí odkaz:
https://doaj.org/article/db373a8e0c5842b99f9f90b027b1fa7c
Autor:
Badr Amul M., Elkholy Omayma, Said Mona, Fahim Sally A., El-Khatib Mohamed, Sabry Dina, Gaber Radwa M.
Publikováno v:
Journal of Medical Biochemistry, Vol 42, Iss 2, Pp 239-248 (2023)
Background: Diabetic Kidney Disease (DKD) is a significant challenge in healthcare. However, there are currently no reliable biomarkers for renal impairment diagnosis, prognosis, or staging in DKD patients. CircRNAs and microRNAs have emerged as noni
Externí odkaz:
https://doaj.org/article/ab5fa69776d54187b1e1038c47e843c5
Autor:
Nicole Roeder, Brittany Richardson, Abrianna Mihalkovic, Samantha Penman, Olivia White, John Hamilton, Ashim Gupta, Kenneth Blum, Mark S. Gold, Panayotis K. Thanos
Publikováno v:
Future Pharmacology, Vol 3, Iss 1, Pp 108-116 (2023)
Emerging evidence indicates that the endogenous cannabinoid system modulates the behavioral and physiological effects of nicotine. Fatty acid-binding proteins (FABPs) are among the primary intracellular trafficking mechanisms of endogenous cannabinoi
Externí odkaz:
https://doaj.org/article/c5d9fdcc2d13432fb1776289d6aa4102
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
In the central nervous system (CNS), cannabinoid receptor 1 (CB1R) is preferentially expressed in axons where it has a unique property, namely resistance to agonist-driven endocytosis. This review aims to summarize what we know about molecular mechan
Externí odkaz:
https://doaj.org/article/df5d42bd43654248a5835939fb35c23b
Autor:
Emanuele Criscuolo, Maria Laura De Sciscio, Angela De Cristofaro, Catalin Nicoara, Mauro Maccarrone, Filomena Fezza
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1678 (2023)
The cannabinoid receptor 1 (CB1R) plays a pivotal role in regulating various physiopathological processes, thus positioning itself as a promising and sought-after therapeutic target. However, the search for specific and effective CB1R ligands has bee
Externí odkaz:
https://doaj.org/article/3345232ca3d74328b377b47826bf4eb8
Akademický článek
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Autor:
Yolanda Paes-Colli, Priscila M. P. Trindade, Louise C. Vitorino, Fabiana Piscitelli, Fabio Arturo Iannotti, Raquel M. P. Campos, Alinny R. Isaac, Andrey Fabiano Lourenço de Aguiar, Silvana Allodi, Fernando G. de Mello, Marcelo Einicker-Lamas, Raphael de Siqueira-Santos, Vincenzo Di Marzo, Bakhos A. Tannous, Litia A. Carvalho, Ricardo A. De Melo Reis, Luzia S. Sampaio
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The endocannabinoid system (ECS) refers to a complex cell-signaling system highly conserved among species formed by numerous receptors, lipid mediators (endocannabinoids) and synthetic and degradative enzymes. It is widely distributed throughout the
Externí odkaz:
https://doaj.org/article/a9d0f0246eb64b048e2d6d0f896f47d1
Autor:
Guangtao Hu, Cuihong Zhou, Jin Wang, Xinxu Ma, Hongzhe Ma, Huan Yu, Zhengwu Peng, Jing Huang, Min Cai
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
IntroductionThis study aimed to identify the effect of electroacupuncture (EA) treatment on post-stroke depression (PSD) and explore whether cannabinoid receptor 1 (CB1R)-mediated mitochondrial biogenesis accounts for the treatment effect of EA.Metho
Externí odkaz:
https://doaj.org/article/6e2db02bb59142d4b01e8c47dcb13fe6