Zobrazeno 1 - 10
of 918
pro vyhledávání: '"cannabidiol (CBD)"'
Autor:
Maheedhar Kodali, Leelavathi N. Madhu, Venkata Sai Vashishta Kolla, Sahithi Attaluri, Charles Huard, Yogish Somayaji, Bing Shuai, Chase Jordan, Xiaolan Rao, Sanath Shetty, Ashok K. Shetty
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-23 (2024)
Abstract Background Chronic Gulf War Illness (GWI) is characterized by cognitive and mood impairments, as well as persistent neuroinflammation and oxidative stress. This study aimed to investigate the efficacy of Epidiolex®, a Food and Drug Administ
Externí odkaz:
https://doaj.org/article/bdbff770ddb04c3cb3105d2ca65a4300
Autor:
Marinella Carone, Marika Premoli, Sara Anna Bonini, Rozana Latsi, Giuseppina Maccarinelli, Maurizio Memo
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39938- (2024)
Cannabis sativa L. produces more than 100 specific bioactive compounds, known as cannabinoids. The major non-psychotropic Cannabis constituent is cannabidiol (CBD), which displays beneficial properties in a variety of medical conditions. However, the
Externí odkaz:
https://doaj.org/article/99cc1188de4e4e5d8ee28b020b2f6e32
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionThere is growing recognition of the potential of cannabis to treat various medical conditions and symptoms, such as chronic pain, spasticity, and epilepsy. However, one of the biggest challenges is the assurance of a standardized cannabis
Externí odkaz:
https://doaj.org/article/262c211fb47540c0bc2cb51d7727edf8
Autor:
Marieka V. DeVuono, Mina G. Nashed, Mohammed H. Sarikahya, Andrea Kocsis, Kendrick Lee, Sebastian R. Vanin, Roger Hudson, Eryn P. Lonnee, Walter J. Rushlow, Daniel B. Hardy, Steven R. Laviolette
Publikováno v:
Neurobiology of Disease, Vol 199, Iss , Pp 106588- (2024)
Clinical and preclinical evidence has demonstrated an increased risk for neuropsychiatric disorders following prenatal cannabinoid exposure. However, given the phytochemical complexity of cannabis, there is a need to understand how specific component
Externí odkaz:
https://doaj.org/article/53c65369598d41a0bca2fd81713316e2
Autor:
Zeeta Bawa, Daniel Lewis, Paul D. Gavin, Roksan Libinaki, Lida Joubran, Mahmoud El-Tamimy, Greg Taylor, Ryan Meltzer, Miguel Bedoya-Pérez, Richard C. Kevin, Iain S. McGregor
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Hand osteoarthritis (OA) is an irreversible degenerative condition causing chronic pain and impaired functionality. Existing treatment options are often inadequate. Cannabidiol (CBD) has demonstrated analgesic and anti-inflammatory effects i
Externí odkaz:
https://doaj.org/article/e6d96969799944a186be375bd57ca0dc
Autor:
Nicholas Aderinto, Gbolahan Olatunji, Emmanuel Kokori, Yusuf Ismaila Ajayi, Olumide Akinmoju, Abiola Samuel Ayedun, Oluwapelumi Ikeoluwa Ayoola, Noah Oluwaseun Aderinto
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-15 (2024)
Abstract Background Dravet Syndrome (DS) is a rare and severe form of childhood epilepsy that is often refractory to conventional antiepileptic drugs. Emerging evidence suggests that Cannabidiol (CBD) offer therapeutic benefits for DS. This review ai
Externí odkaz:
https://doaj.org/article/3baf8e4a778546f3a4c89c8a633a3c1f
Publikováno v:
Journal of Cannabis Research, Vol 6, Iss 1, Pp 1-26 (2024)
Abstract Background The treatment of diverse diseases using plant-derived products is actively encouraged. In the past few years, cannabidiol (CBD) has emerged as a potent cannabis-derived drug capable of managing various debilitating neurological in
Externí odkaz:
https://doaj.org/article/57108aba3adf433a861833a696279f66
Autor:
Mariam Melkumyan, Vibha M. Annaswamy, Alexandra M. Evans, Opeyemi F. Showemimo, Zari E. McCullers, Dongxiao Sun, Terrence E. Murphy, Kent E. Vrana, Amy C. Arnold, Wesley M. Raup-Konsavage, Yuval Silberman
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionAlcohol use disorder (AUD) is commonly associated with anxiety disorders and enhanced stress-sensitivity; symptoms that can worsen during withdrawal to perpetuate continued alcohol use. Alcohol increases neuroimmune activity in the brain.
Externí odkaz:
https://doaj.org/article/14bb70362fb04fa2aa84c2d359888e79
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
Various countries and US States have legalized cannabis, and the use of the psychoactive1 and non-psychoactive cannabinoids is steadily increasing. In this review, we have collated evidence from published non-clinical and clinical sources to evaluate
Externí odkaz:
https://doaj.org/article/351461b43e3f4fb2873ef3a0c74eab5b
Autor:
Kevin Brown, Kyle Funk, Alexa Figueroa Barrientos, Ashly Bailey, Sarah Shrader, Wenke Feng, Craig J. McClain, Zhao-Hui Song
Publikováno v:
Cells, Vol 13, Iss 19, p 1618 (2024)
Cannabidiol (CBD) is a major non-psychotropic phytocannabinoid that exists in the Cannabis sativa plant. CBD has been found to act on various receptors, including both cannabinoid and non-cannabinoid receptors. In addition, CBD has antioxidant effect
Externí odkaz:
https://doaj.org/article/586e551b8d4041adb2e6c5f0e2adf7f2