Zobrazeno 1 - 10
of 89
pro vyhledávání: '"cancer-testis gene"'
Autor:
Dandan Li, Lingyun Xia, Pan Huang, Zidi Wang, Qiwei Guo, Congcong Huang, Weidong Leng, Shanshan Qin
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Background Cancer/testis (CT) antigens/genes are usually overexpressed in cancers and exhibit high immunogenicity, making them promising targets for immunotherapy and cancer vaccines. The role of serine protease PRSS56 in cancers remains unk
Externí odkaz:
https://doaj.org/article/c58fed009fe043bfbeda73a254e904fa
Autor:
Yayun Gu, Cheng Wang, Rongxuan Zhu, Jianshui Yang, Wenwen Yuan, Yanhui Zhu, Yan Zhou, Na Qin, Hongbing Shen, Hongxia Ma, Hongxia Wang, Xiaoan Liu, Zhibin Hu
Publikováno v:
Cancer Biology & Medicine, Vol 18, Iss 1, Pp 74-87 (2021)
Objective: The newly defined cancer-testis (CT) gene, MEIOB, was previously found to play key roles in DNA double-strand break (DSB) repair. In this study, we aimed to investigate the effects and mechanisms of MEIOB in the carcinogenesis of triple-ne
Externí odkaz:
https://doaj.org/article/6eafafab5c3c436e85a62f6492930055
Autor:
Lijuan Meng, Yan Zhou, Sihan Ju, Jing Han, Ci Song, Jing Kong, Yifei Wu, Shuai Lu, Jiani Xu, Wenwen Yuan, Erbao Zhang, Cheng Wang, Zhibin Hu, Yayun Gu, Rongcheng Luo, Xuehao Wang
Publikováno v:
Cancer Medicine, Vol 8, Iss 14, Pp 6476-6484 (2019)
Abstract Purpose The overexpression and knockdown of PLK4 were both reported to generate aneuploidy. Thus, we aimed to investigate whether genetic variants in PLK4 contribute to the development of hepatocellular carcinoma (HCC). Methods We evaluated
Externí odkaz:
https://doaj.org/article/61b99de8bf924618b332fc77695fe369
Autor:
Yuting Chang, Xuewei Wang, Yide Xu, Liu Yang, Qufei Qian, Sihan Ju, Yao Chen, Shuaizhou Chen, Na Qin, Zijian Ma, Juncheng Dai, Hongxia Ma, Guangfu Jin, Erbao Zhang, Cheng Wang, Zhibin Hu
Publikováno v:
Cancer Medicine, Vol 8, Iss 7, Pp 3511-3519 (2019)
Abstract Cancer‐testis (CT) genes are a group of genes restrictedly expressed in testis and multiple cancers and can serve as candidate driver genes participating in the development of cancers. Our previous study identified a number of CT genes in
Externí odkaz:
https://doaj.org/article/9d94d5075bc34bf69c53b20163802523
Autor:
Yongfei Li, Jiahui Chu, Jun Li, Wanting Feng, Fan Yang, Yifan Wang, Yanhong Zhang, Chunxiao Sun, Mengzhu Yang, Shauna N. Vasilatos, Yi Huang, Ziyi Fu, Yongmei Yin
Publikováno v:
Molecular Oncology, Vol 12, Iss 8, Pp 1233-1248 (2018)
Placenta‐specific protein 1 (Plac1) is a cancer/testis antigen that plays a critical role in promoting cancer initiation and progression. However, the clinical significance and mechanism of Plac1 in cancer progression remain elusive. Here, we repor
Externí odkaz:
https://doaj.org/article/d17895e6b1d64192b6e73a428ab87d81
Akademický článek
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Autor:
Vicente Planells-Palop, Ali Hazazi, Julia Feichtinger, Jana Jezkova, Gerhard Thallinger, Naif O. Alsiwiehri, Mikhlid Almutairi, Lee Parry, Jane A. Wakeman, Ramsay J. McFarlane
Publikováno v:
Molecular Cancer, Vol 16, Iss 1, Pp 1-18 (2017)
Abstract Background Cancer/testis (CT) genes have expression normally restricted to the testis, but become activated during oncogenesis, so they have excellent potential as cancer-specific biomarkers. Evidence is starting to emerge to indicate that t
Externí odkaz:
https://doaj.org/article/173a926d7ccd41439322b850a8a214a4
Akademický článek
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Autor:
Litvinov, Jennifer Gantchev, Julia Messina-Pacheco, Amelia Martínez Villarreal, Brandon Ramchatesingh, Philippe Lefrançois, Pingxing Xie, Laetitia Amar, Hong Hao Xu, Keerthenan Raveendra, Daniel Sikorski, Daniel Josue Guerra Ordaz, Raman Preet Kaur Gill, Marine Lambert, Ivan V.
Publikováno v:
Cells; Volume 12; Issue 12; Pages: 1627
Genomic instability is a prominent hallmark of cancer, however the mechanisms that drive and sustain this process remain elusive. Research demonstrates that numerous cancers with increased levels of genomic instability ectopically express meiosis-spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::688443ba17d64b54a37b4b4ceb2539c7
Publikováno v:
PeerJ, Vol 6, p e5822 (2018)
Aim Anaplastic thyroid carcinoma (ATC) is the most lethal thyroid malignancy. Identification of novel drug targets is urgently needed. Materials & Methods We re-analyzed several GEO datasets by systematic retrieval and data merging. Differentially ex
Externí odkaz:
https://doaj.org/article/dd68f9775bbc44c48335786b06e0ac93