Zobrazeno 1 - 10
of 468
pro vyhledávání: '"cancer-induced bone pain"'
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Malignant bone tumors, including primary bone cancer and metastatic bone tumors, are a significant clinical challenge due to their high frequency of presentation, poor prognosis and lack of effective treatments and therapies. Bone tumors are
Externí odkaz:
https://doaj.org/article/9e7f503b98fd4fa8888a72936d7eb00c
Autor:
Longsheng Xu, Shang Zheng, Liping Chen, Lei Yang, Shuyao Zhang, Beibei Liu, Kangli Shen, Qinli Feng, Qinghe Zhou, Ming Yao
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102200- (2024)
Cancer-induced bone pain (CIBP) significantly impacts the quality of life and survival of patients with advanced cancer. Despite the established role of neurexins in synaptic structure and function, their involvement in sensory processing during inju
Externí odkaz:
https://doaj.org/article/f185a962fe494e708e7e91ccb0c177ec
Autor:
Yang Heyu, Wang Yujia, Zhen Shuqing, Wang Banghua, Jiao Ming, Liu Ling, Li Dai, Zhu Haili, Xie Min
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 55, Pp 460-471 (2023)
Bone metastasis of cancer cells leads to severe pain by disrupting bone structure and inducing central sensitization. Neuroinflammation in the spinal cord plays a decisive role in the maintenance and development of pain. In the current study, male Sp
Externí odkaz:
https://doaj.org/article/eb683277171c48c39991711347d6d63d
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-23 (2022)
Abstract Purpose Metastatic spread of prostate cancer to the skeleton may result in debilitating bone pain. In this review, we address mechanisms underpinning the pathobiology of metastatic prostate cancer induced bone pain (PCIBP) that include sensi
Externí odkaz:
https://doaj.org/article/19f1f600843041ae916017cf971aab3e
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Cancer-induced bone pain (CIBP) caused by bone metastasis is one of the most prevalent diseases, and current treatments rely primarily on opioids, which have significant side effects. However, recent developments in pharmaceutical science have identi
Externí odkaz:
https://doaj.org/article/619cbdabaef04f68a82a2aecd5f172fe
Akademický článek
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Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Cancer-induced bone pain (CIBP) has a considerable impact on patients’ quality of life as well as physical and mental health. At present, patients with CIBP are managed according to the three-step analgesic therapy algorithm proposed by the World H
Externí odkaz:
https://doaj.org/article/d6931561f9e04753949539b6596a7c02
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Objective Cancer-induced bone pain (CIBP) is a kind of pain with complex pathophysiology. Proteinase-activated receptor 2 (PAR-2) is involved in CIBP. This study explored the effects of PAR-2 on CIBP rats. Methods CIBP rat model was establis
Externí odkaz:
https://doaj.org/article/0382dcea9ede40cb8b2a8ac7cca041fa
Publikováno v:
Journal of Advanced Research, Vol 35, Iss , Pp 117-127 (2022)
Background: Cancer-induced Bone Pain (CIBP) is an important factor affecting their quality of life of cancer survivors. In addition, current clinical practice and scientific research suggest that neuropathic pain is a representative component of CIBP
Externí odkaz:
https://doaj.org/article/cf95df803cba42efb0a2438d1d242940
Publikováno v:
Frontiers in Pain Research, Vol 3 (2023)
Personalised and targeted interventions have revolutionised cancer treatment and dramatically improved survival rates in recent decades. Nonetheless, effective pain management remains a problem for patients diagnosed with cancer, who continue to suff
Externí odkaz:
https://doaj.org/article/c3689603ce3a4af9914ac8096d04dff2