Zobrazeno 1 - 10
of 152
pro vyhledávání: '"cancer-cell survival"'
Autor:
Kausik Bishayee, Khadija Habib, Uddin Md. Nazim, Jieun Kang, Aniko Szabo, Sung-Oh Huh, Ali Sadra
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Neuronal-origin HuD (ELAVL4) is an RNA binding protein overexpressed in neuroblastoma (NB) and certain other cancers. The RNA targets of this RNA binding protein in neuroblastoma cells and their role in promoting cancer survival h
Externí odkaz:
https://doaj.org/article/ef37e761922142939051865a225d00c7
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-9 (2021)
Abstract Prostate cancer is the most common solid organ malignancy in the United States, and has the highest probability of all cancers in becoming invasive. New molecular targets are needed to define and impede the growth and progression of advanced
Externí odkaz:
https://doaj.org/article/c624955bc4414a9d99ea71b8f4f5f5b5
Autor:
Andrés Gámez-García, Idoia Bolinaga-Ayala, Guillermo Yoldi, Sergio Espinosa-Gil, Nora Diéguez-Martínez, Elisabet Megías-Roda, Pau Muñoz-Guardiola, Jose M. Lizcano
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Autophagy is a highly conserved intracellular process that preserves cellular homeostasis by mediating the lysosomal degradation of virtually any component of the cytoplasm. Autophagy is a key instrument of cellular response to several stresses, incl
Externí odkaz:
https://doaj.org/article/b087629e9a314cc7945f694a47bb7246
Autor:
Vitalyi Senyuk, Najmeh Eskandari, Ying Jiang, Rebeca Garcia-Varela, Rachel Sundstrom, Luigi Leanza, Roberta Peruzzo, Mark Burkard, Richard D. Minshall, Saverio Gentile
Publikováno v:
Redox Biology, Vol 45, Iss , Pp 102030- (2021)
Potassium channels are important regulators of cellular homeostasis and targeting these proteins pharmacologically is unveiling important mechanisms in cancer cell biology. Here we demonstrate that pharmacological stimulation of the Kv11.1 potassium
Externí odkaz:
https://doaj.org/article/09ec8a0b65244902861e4b4ce6051d36
Publikováno v:
Cancer Management and Research, Vol Volume 11, Pp 3171-3185 (2019)
Hui-Feng Gao,1,2,* Lian-Yu Chen,1,2,* Chien-Shan Cheng,1,2 Hao Chen,1,2 Zhi-Qiang Meng,1,2 Zhen Chen1,21Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, People’s Republic of China; 2Department of Integrative Onco
Externí odkaz:
https://doaj.org/article/93a44fd27e5e471fb377237a379104a6
Autor:
Petr Tomek, Shanti K. Gore, Chloe L. Potts, Cristin G. Print, Michael A. Black, Ariane Hallermayr, Michael Kilian, Evelyn Sattlegger, Lai-Ming Ching
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-15 (2018)
Abstract Background Depletion of tryptophan and the accumulation of tryptophan metabolites mediated by the immunosuppressive enzyme indoleamine 2,3-dioxygenase 1 (IDO1), trigger immune cells to undergo apoptosis. However, cancer cells in the same mic
Externí odkaz:
https://doaj.org/article/ba904e871d9947f4afac06258adc6a56
Publikováno v:
Methods in Molecular Biology. 2451:405-480
Photodynamic therapy (PDT) is a minimally to noninvasive treatment modality that has emerged as a promising alternative to conventional cancer treatments. PDT induces hyperoxidative stress and disrupts cellular homeostasis in photosensitized cancer c
Autor:
Ziling Fang, Bo Cao, Jun-Ming Liao, Jun Deng, Kevin D Plummer, Peng Liao, Tao Liu, Wensheng Zhang, Kun Zhang, Li Li, David Margolin, Shelya X Zeng, Jianping Xiong, Hua Lu
Publikováno v:
eLife, Vol 7 (2018)
Ribosomal proteins (RPs) play important roles in modulating the MDM2-p53 pathway. However, less is known about the upstream regulators of the RPs. Here, we identify SPIN1 (Spindlin 1) as a novel binding partner of human RPL5/uL18 that is important fo
Externí odkaz:
https://doaj.org/article/2318789eb2a14269b8a96a4ddc9cb9b1
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-9 (2021)
Molecular Biomedicine
Molecular Biomedicine
Prostate cancer is the most common solid organ malignancy in the United States, and has the highest probability of all cancers in becoming invasive. New molecular targets are needed to define and impede the growth and progression of advanced prostate
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