Zobrazeno 1 - 10
of 124
pro vyhledávání: '"cancer-associated fibroblasts (CAF)"'
Autor:
Fatemeh Eskandari-Malayeri, Marzieh Rezeai, Tahmineh Narimani, Nafiseh Esmaeil, Mahdieh Azizi
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Fusobacterium nucleatum, (F. nucleatum) as a known factor in inducing oncogenic, invasive, and inflammatory responses, can lead to an increase in the incidence and progression of colorectal cancer (CRC). Cancer-associated fibroblasts (CAF) a
Externí odkaz:
https://doaj.org/article/ef2d5702d4994ac7be5ae293fa34bde1
Autor:
Vladan Milosevic, Arne Östman
Publikováno v:
Upsala Journal of Medical Sciences, Vol 129, Pp 1-12 (2024)
Cancer-associated fibroblasts (CAFs) are a heterogeneous cell population recognized as a key component of the tumour microenvironment (TME). Cancer-associated fibroblasts are known to play an important role in maintaining and remodelling the extracel
Externí odkaz:
https://doaj.org/article/49576ea65a9b4a4c971364719cff2b1b
Autor:
Carlo P. Ramil, Handan Xiang, Peng Zhang, Aileen Cronin, Lisia Cabral, Zhizhang Yin, Josephine Hai, Huijun Wang, Benjamin Ruprecht, Yanlin Jia, Dongyu Sun, Hongmin Chen, An Chi
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTMyeloid cells are known to play a crucial role in creating a tumor-promoting and immune suppressive microenvironment. Our previous study demonstrated that primary human monocytes can be polarized into immunosuppressive myeloid-derived suppres
Externí odkaz:
https://doaj.org/article/0a8619fc60474ca5893566aab3adaec4
Autor:
Ntlotlang Mokgautsi, Alexander TH Wu, Sheng-Yao Cheng, Jih-Chin Lee, Thomashire Anita George, Jia-Hong Chen
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 3, Pp 105561- (2024)
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive cancer affecting over half a million people worldwide each year. Although recent FDA-approved treatments, like cetuximab, have shown promise, the five-year survival rate remains bel
Externí odkaz:
https://doaj.org/article/b3ee116482564b0baee3bfe0fe3f4f50
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Hepatocellular carcinoma (HCC) is a highly aggressive malignancy, with high recurrence rates and notorious resistance to conventional chemotherapy. Cancer stemness refers to the stem-cell-like phenotype of cancer cells and has been recognized to play
Externí odkaz:
https://doaj.org/article/464b5f8e22a541edb0c3e39a7ee70c5e
Publikováno v:
Cells, Vol 13, Iss 12, p 1057 (2024)
Diffuse large B cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma worldwide, constituting around 30–40% of all cases. Almost 60% of patients develop relapse of refractory DLBCL. Among the reasons for the therapy failure, tumour
Externí odkaz:
https://doaj.org/article/52caac3063614bb598260447be1ac577
Autor:
Philip Chiu‐Tsun Tang, Max Kam‐Kwan Chan, Jeff Yat‐Fai Chung, Alex Siu‐Wing Chan, Dongmei Zhang, Chunjie Li, Kam‐Tong Leung, Calvin Sze‐Hang Ng, Yi Wu, Ka‐Fai To, Hui‐Yao Lan, Patrick Ming‐Kuen Tang
Publikováno v:
Advanced Science, Vol 11, Iss 1, Pp n/a-n/a (2024)
Abstract Macrophage‐myofibroblast transition (MMT) is a newly discovered pathway for mass production of pro‐tumoral cancer‐associated fibroblasts (CAFs) in non‐small cell lung carcinoma (NSCLC) in a TGF‐β1/Smad3 dependent manner. Better un
Externí odkaz:
https://doaj.org/article/87ee915054aa49ad8d44d285ae662e18
Autor:
Dalton T. McLean, Jennifer J. Meudt, Loren D. Lopez Rivera, Dominic T. Schomberg, Derek M. Pavelec, Tyler T. Duellman, Darya G. Buehler, Patrick B. Schwartz, Melissa Graham, Laura M. Lee, Keri D. Graff, Jamie L. Reichert, Sandra S. Bon-Durant, Charles M. Konsitzke, Sean M. Ronnekleiv-Kelly, Dhanansayan Shanmuganayagam, C. Dustin Rubinstein
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Neurofibromatosis Type 1 (NF1) is one of the most common genetically inherited disorders that affects 1 in 3000 children annually. Clinical manifestations vary widely but nearly always include the development of cutaneous, plexiform and diffuse neuro
Externí odkaz:
https://doaj.org/article/0f275dea337648fba3fdc744507e7930
Autor:
Yunlong Zhang, Yue Ma, Qingqing Liu, Yifei Du, Liang Peng, Jianwu Zhou, Zhenzhen Zhao, Changchun Li, Shan Wang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Neuroblastoma(NB) is the most common extracranial solid tumor in childhood, and it is now believed that some patients with NB have an underlying genetic susceptibility, which may be one of the reasons for the multiplicity of NB patients within a fami
Externí odkaz:
https://doaj.org/article/f191ec12b423413e935f4c5cd3567989
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundsBladder cancer (BLCA) is one of the most prevalent cancers of the genitourinary system, the clinical outcomes of patients with BLCA are bad, and the morbidity rate is high. One of the key components of the tumor microenvironment (TME) is c
Externí odkaz:
https://doaj.org/article/298f0c49f70d496fb5c73edaeab18ff7