Zobrazeno 1 - 10
of 1 486
pro vyhledávání: '"cancer targeting"'
Autor:
Sandile Phinda Songca
Publikováno v:
Journal of Photochemistry and Photobiology, Vol 23, Iss , Pp 100245- (2024)
Metal organic frameworks (MOFs) consist of metal atoms or clusters, coordinated to organic ligands to form macromolecular super structures, with pores large enough to host free drug molecules, including photodynamic therapy (PDT) photosensitizers. Th
Externí odkaz:
https://doaj.org/article/bf209d1c5c4f42eb807a3af3a61dcd72
Autor:
Shahira F. El Menshawe, Khaled Shalaby, Mohammed H. Elkomy, Heba M. Aboud, Yasmin M. Ahmed, Abdelmeged A. Abdelmeged, Marwa Elkarmalawy, Mahmoud A. Abou Alazayem, Amani M. El Sisi
Publikováno v:
International Journal of Pharmaceutics: X, Vol 7, Iss , Pp 100225- (2024)
Celecoxib (CLX), a selective inhibitor for cyclooxygenase 2 (COX-2), has manifested potential activity against diverse types of cancer. However, low bioavailability and cardiovascular side effects remain the major challenges that limit its exploitati
Externí odkaz:
https://doaj.org/article/18ff790bc59241c08c65b14e5a612d8d
Autor:
Yifan Jiang, Hongjian Chen, Tao Lin, Chao Zhang, Jiaxin Shen, Jifan Chen, Yanan Zhao, Wen Xu, Guowei Wang, Pintong Huang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Off-targeted distribution of chemotherapeutic drugs causes severe side effects, further leading to poor prognosis and patient compliance. Ligand/receptor-mediated targeted drug delivery can improve drug accumulation in the tumor b
Externí odkaz:
https://doaj.org/article/1ec9d0931be941e6986be916a35f3e6a
Autor:
Maria Bibika, Panagiotis Kanellopoulos, Maritina Rouchota, George Loudos, Berthold A. Nock, Eric P. Krenning, Theodosia Maina
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1223 (2024)
Background: The concept of radiotheranostics relies on the overexpression of a biomolecular target on malignant cells to direct diagnostic/therapeutic radionuclide-carriers specifically to cancer lesions. The concomitant expression of more than one t
Externí odkaz:
https://doaj.org/article/95e76b12426f4ce9b6e24d4e6a8838e3
Publikováno v:
Bioactive Materials, Vol 24, Iss , Pp 524-534 (2023)
Zwitterionic polymers are known to interact with cells and have been shown to reveal cancer cell specificity. In this work, the importance of the chemistry of the polymer backbone for the cellular specificity of amino-acid-derived polyzwitterions is
Externí odkaz:
https://doaj.org/article/984a404ccac145739fb6fdadb6eb662d
Advanced cancer targeting using aptamer functionalized nanocarriers for site-specific cargo delivery
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-36 (2023)
Abstract The non-specificity of standard anticancer therapies has profound detrimental consequences in clinical treatment. Therapeutic specificity can be precisely achieved using cutting-edge ligands. Small synthetic oligonucleotide-ligands chosen th
Externí odkaz:
https://doaj.org/article/7ef9b2c3b28d4547a5a458b1e0f9c6fd
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Pancreatic cancer is a devastating disease with a high mortality rate and a lack of effective therapies. The challenges associated with early detection and the highly aggressive nature of pancreatic cancer have limited treatment options, underscoring
Externí odkaz:
https://doaj.org/article/0e4910b0248c4ea5831f96f34a8e193b
Autor:
Khaled AbouAitah, Heba A. Hassan, Naglaa M. Ammar, Doha H. Abou Baker, Imane M. Higazy, Olfat G. Shaker, Ahmed A. A. Elsayed, Abeer M. E. Hassan
Publikováno v:
Cancer Nanotechnology, Vol 14, Iss 1, Pp 1-32 (2023)
Abstract Introduction Essential oils (EOs) are complex structures and possess several pharmacological effects. Nanomedicine offers a solution for their major limitations, including poor solubility, volatility, and non–controlled release, preventing
Externí odkaz:
https://doaj.org/article/b06c430856b740bab0e3355a9f420989
Autor:
Xiaoying Li, Yanzi Yu, Qi Chen, Jiabao Lin, Xueqiong Zhu, Xiaoting Liu, Lizhen He, Tianfeng Chen, Weiling He
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background Cancer cell membrane-camouflaged nanotechnology for metal complex can enhance its biocompatibility and extend the effective circulation time in body. The ruthenium polypyridyl complex (RuPOP) has extensive antitumor activity, but
Externí odkaz:
https://doaj.org/article/8b51f7387a664baf8f570486e3e17bc0
Publikováno v:
Molecules, Vol 28, Iss 21, p 7398 (2023)
The aim of this study is to prepare redox-sensitive nanophotosensitizers for the targeted delivery of chlorin e6 (Ce6) against cervical cancer. For this purpose, Ce6 was conjugated with β-cyclodextrin (bCD) via a disulfide bond, creating nanophotose
Externí odkaz:
https://doaj.org/article/8c81add168724b8cb14414c9eda001e1