Zobrazeno 1 - 10
of 50
pro vyhledávání: '"cancer selectivity"'
Autor:
Hengmao Zhang, Haobo Zhao, Ming Chi, Kaizhen Yang, Yukang Chen, Jiahui Mao, Peilin Li, Zukang Wang, Faqiao Song, Wenxuan Guo, Miyu Sakai, Junko Takahashi
Publikováno v:
AIMS Bioengineering, Vol 10, Iss 2, Pp 89-110 (2023)
Background: At present, radiotherapy (RT) is widely used in cancer treatment, but traditional RT methods using ionizing radiation cannot avoid damage to normal tissues. Therefore, the development of a more precise RT is an important research directi
Externí odkaz:
https://doaj.org/article/cef74eb6a5ed4aebae25f429dac83753
Akademický článek
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Autor:
Scott McComb, Tina Nguyen, Alex Shepherd, Kevin A. Henry, Darin Bloemberg, Anne Marcil, Susanne Maclean, Ahmed Zafer, Rénald Gilbert, Christine Gadoury, Robert A. Pon, Traian Sulea, Qin Zhu, Risini D. Weeratna
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Epidermal growth factor family receptor (EGFR) is commonly overexpressed in many solid tumors and an attractive target for chimeric antigen receptor (CAR)-T therapy, but as EGFR is also expressed at lower levels in healthy tissues a therapeutic strat
Externí odkaz:
https://doaj.org/article/937b7637066e4c68807a453d8653a886
Autor:
Ferenc Kovács, Dóra Izabella Adamecz, Ferenc István Nagy, Benedek Papp, Mónika Kiricsi, Éva Frank
Publikováno v:
Molecules, Vol 27, Iss 21, p 7456 (2022)
Hybridization of steroids and other pharmacophores often modifies the bioactivity of the parent compounds, improving selectivity and side effect profile. In this study, estradiol and 3′-(un)substituted benzisoxazole moieties were combined into nove
Externí odkaz:
https://doaj.org/article/f25e1c617d3e480c840a6cd5bdaf70e4
Autor:
Piyush A. Patel, Tanja Bruun, Polina Ilina, Heidi Mäkkylä, Antti Lempinen, Jari Yli-Kauhaluoma, Päivi Tammela, Paula S. Kiuru
Publikováno v:
Marine Drugs, Vol 19, Iss 7, p 400 (2021)
Marine-originated spirocyclic bromotyrosines are considered as promising scaffolds for new anticancer drugs. In a continuation of our research to develop potent and more selective anticancer compounds, we synthesized a library of 32 spirocyclic clava
Externí odkaz:
https://doaj.org/article/3d2ceae9c2064744a6b379da36921291
Publikováno v:
Viruses, Vol 7, Iss 11, Pp 5767-5779 (2015)
Various viruses have been studied and developed for oncolytic virotherapies. In virotherapy, a relatively small amount of viruses used in an intratumoral injection preferentially replicate in and lyse cancer cells, leading to the release of amplified
Externí odkaz:
https://doaj.org/article/0da0f1b5cdf64a10bad9e4282f3e5b8b
Autor:
McComb, Scott, Nguyen, Tina, Shepherd, Alex, Henry, Kevin A., Bloemberg, Darin, Marcil, Anne, Maclean, Susanne, Zafer, Ahmed, Gilbert, Rénald, Gadoury, Christine, Pon, Robert A., Sulea, Traian, Zhu, Qin, Weeratna, Risini D.
Publikováno v:
Frontiers in Immunology. 13
Epidermal growth factor family receptor (EGFR) is commonly overexpressed in many solid tumors and an attractive target for chimeric antigen receptor (CAR)-T therapy, but as EGFR is also expressed at lower levels in healthy tissues a therapeutic strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333ff510c658ef6a0e511a7cbd23952f
https://doi.org/10.3389/fimmu.2022.864868
https://doi.org/10.3389/fimmu.2022.864868
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Takeo eTatsuta, Sigeki eSugawara, Kohta eTakahashi, Yukiko eOgawa, Masahiro eHosono, Kazuo eNitta
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
Sialic acid-binding lectin (SBL) is a multifunctional protein that is isolated from oocytes of Rana catesbeiana. It has both lectin and ribonuclease (enzyme) properties, and therefore is called leczyme. We examined the antitumor effects of SBL and di
Externí odkaz:
https://doaj.org/article/39bc55a4aa84450288ed55d89f7225fb