Zobrazeno 1 - 10
of 236
pro vyhledávání: '"cancer predisposition syndromes"'
Autor:
Mohammad-Salar Hosseini
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Li-Fraumeni syndrome is a rare yet serious hereditary cancer predisposition syndrome, marked by a significant early-life increased risk of developing cancer. Primarily caused by germline mutations in the TP53 tumor suppressor gene, Li-Fraume
Externí odkaz:
https://doaj.org/article/aecc43d7f67e455792eb44d253f6c621
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Medulloblastoma is the most common malignant pediatric brain tumor and has been linked to known cancer predisposition syndromes. We report a case of medulloblastoma of a 12-year-old Indo-Trinidadian female with a strong family history of colorectal c
Externí odkaz:
https://doaj.org/article/a5293d13b76f48f4bbfadbd38d2d0814
Autor:
D. Yu. Kachanov, R. T. Abdullaev, T. V. Shamanskaya, Ye. V. Inyushkina, K. V. Dobrenkov, R. F. Savkova, S. R. Varfolomeeva
Publikováno v:
Онкогематология, Vol 0, Iss 3, Pp 29-35 (2022)
The aim of the study was to assess the prevalence of cancer predisposition syndromes among children with cancer in Moscow Region (MR). The data on patients were retrieved from the database of Childhood Population-based Cancer Registry of MR. 35 (3.0
Externí odkaz:
https://doaj.org/article/02d9d9d97f244888a36e09149ac62ccc
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Autor:
Kefeng Shen, Meilan Zhang, Jiachen Wang, Wei Mu, Jin Wang, Chunyan Wang, Shugang Xing, Zhenya Hong, Min Xiao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Fanconi anemia (FA) genes play critical roles in the repair of DNA lesions. Non-FA (or underlying FA) patients harboring heterozygous germline FA gene mutations may also face an increased risk of developing bone marrow failure, primary immunodeficien
Externí odkaz:
https://doaj.org/article/9da416af588446f08a971c31604aa349
Autor:
Ioana Balinisteanu, Monica-Cristina Panzaru, Lavinia Caba, Maria-Christina Ungureanu, Andreea Florea, Ana Maria Grigore, Eusebiu Vlad Gorduza
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2143 (2023)
Cancer predisposition syndromes are entities determined especially by germinal pathogenic variants, with most of them autosomal dominantly inherited. The risk of a form of cancer is variable throughout life and affects various organs, including the t
Externí odkaz:
https://doaj.org/article/e51aa494f3ff4db68dabbebdc9aa386a
Autor:
Cara N. Cacioppo, Brian L. Egleston, Dominique Fetzer, Colleen Burke Sands, Syeda A. Raza, Neeraja Reddy Malleda, Elisabeth McCarty Wood, India Rittenburg, Julianne Childs, David Cho, Martha Hosford, Tina Khair, Jamil Khatri, Lydia Komarnicky, Trina Poretta, Fahd Rahman, Satish Shah, Linda J. Patrick‐Miller, Susan M. Domchek, Angela R. Bradbury
Publikováno v:
Cancer Medicine, Vol 10, Iss 13, Pp 4532-4541 (2021)
Abstract Purpose To examine the benefit of telehealth over current delivery options in oncology practices without genetic counselors. Methods Participants meeting cancer genetic testing guidelines were recruited to this multi‐center, randomized tri
Externí odkaz:
https://doaj.org/article/eda538bc81684e22bb8ecc438ecbcee5
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Although most non-melanoma skin cancers are felt to be sporadic in origin, these tumors do play a role in several cancer predisposition syndromes. The manifestations of skin cancers in these hereditary populations can include diagnosis at extremely e
Externí odkaz:
https://doaj.org/article/4c4f91c2b9624a39ba5e12d543f141e4
Autor:
Marek W. Karwacki
Publikováno v:
Contemporary Oncology, Vol 24, Iss 2, Pp 140-144 (2020)
The main goal of this study was to draw the attention of physicians to commonly undisclosed risk of breast cancer (BrCa) in women suffering from neurofibromatosis type 1 (NF-1), which is 5-fold higher than in the general population. NF-1 related BrCa
Externí odkaz:
https://doaj.org/article/271f7a2bcdea4aca883d4eed06be7693
Publikováno v:
Medicina, Vol 58, Iss 10, p 1386 (2022)
In the last two decades, thanks to the data that have been obtained from the Human Genome Project and the development of next-generation sequencing (NGS) technologies, research in oncology has produced extremely important results in understanding the
Externí odkaz:
https://doaj.org/article/d4c98d8b5f514fe0ac7c29ba21bf151f