Zobrazeno 1 - 10
of 102
pro vyhledávání: '"cancer plasticity"'
Autor:
Jonathan A. Kelber, Marcin Iwanicki, Marianna Kruithof-de Julio, Benjamin T. Spike, Michelle M. Martínez-Montemayor
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/efb0931fd4e049bbb58307e3133141c7
Autor:
Peng, Qiuxia a, b, †, Li, Xiaolong c, †, Fang, Chao a, †, Zhu, Chunyan a, b, Wang, Taixia a, b, Yin, Binxu a, Dong, Xiulin a, Guo, Huaijuan a, d, Liu, Yang a, d, Zhang, Kun a, ⁎
Publikováno v:
In Acta Pharmaceutica Sinica B November 2024
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Triple-negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer. Core transcriptional regulatory circuitry (CRC) consists of autoregulated transcription factors (TFs) and their enhancers, which dominate gene expression progra
Externí odkaz:
https://doaj.org/article/4e75918888dd4147a545aa8ac5814192
Autor:
Rui-Zhi Tang, Xi-Qiu Liu
Publikováno v:
Materials Today Bio, Vol 19, Iss , Pp 100607- (2023)
Clinical evidence supports a role for the extracellular matrix (ECM) in cancer plasticity across multiple tumor types. The lack of in vitro models that represent the native ECMs is a significant challenge for cancer research and drug discovery. There
Externí odkaz:
https://doaj.org/article/58412dade38240878baa01f6324bec70
Publikováno v:
Cells, Vol 12, Iss 20, p 2486 (2023)
Modulation of autophagy as an anticancer strategy has been widely studied and evaluated in several cell models. However, little attention has been paid to the metabolic changes that occur in a cancer cell when autophagy is inhibited or induced. In th
Externí odkaz:
https://doaj.org/article/04ddbca83f114a84a41262836e115d65
Publikováno v:
生物医学转化, Vol 2, Iss 1, Pp 39-49 (2021)
Lung cancer, featured with strong heterogeneity and plasticity, is the most devastating diseaseworldwide. Based on histological classification, lung cancer can be categorized as small cell lung cancer(SCLC) and non-small cell lung cancer (NSCLC), amo
Externí odkaz:
https://doaj.org/article/d8f97e1066164879a7e87e47c10bb482
Autor:
Jan Remsik, Yudan Chi, Xinran Tong, Ugur Sener, Camille Derderian, Abigail Park, Fadi Saadeh, Tejus Bale, Adrienne Boire
Publikováno v:
Cancer Reports, Vol 5, Iss 4, Pp n/a-n/a (2022)
Abstract Background Leptomeningeal metastasis (LM), or spread of cancer cells into the cerebrospinal fluid (CSF), is characterized by a rapid onset of debilitating neurological symptoms and markedly bleak prognosis. The lack of reproducible in vitro
Externí odkaz:
https://doaj.org/article/95974a54e7b14fedb35845edf380dcfd
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/fb2195beb2164e65b397881851a62ef3
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The processes of recurrence and metastasis, through which cancer relapses locally or spreads to distant sites in the body, accounts for more than 90% of cancer-related deaths. At present there are very few treatment options for patients at this stage
Externí odkaz:
https://doaj.org/article/54445c1b5de4490ab194b451a7453d5d
Autor:
Delphine Garnier, Ophélie Renoult, Marie-Clotilde Alves-Guerra, François Paris, Claire Pecqueur
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Over the years, substantial evidence has definitively confirmed the existence of cancer stem-like cells within tumors such as Glioblastoma (GBM). The importance of Glioblastoma stem-like cells (GSCs) in tumor progression and relapse clearly highlight
Externí odkaz:
https://doaj.org/article/51bc8c0e6fa842459784da94a8ecf334