Zobrazeno 1 - 10
of 487
pro vyhledávání: '"cancer mutations"'
Autor:
Dong-Jin Han, Sunmin Kim, Seo-Young Lee, Youngbeen Moon, Su Jung Kang, Jinseon Yoo, Hye Young Jeong, Hae Jin Cho, Jeong Yang Jeon, Byeong Chang Sim, Jaehoon Kim, Seungho Lee, Ruibin Xi, Tae-Min Kim
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background Determining the impact of somatic mutations requires understanding the functional relationship of genes acquiring mutations; however, it is largely unknown how mutations in functionally related genes influence each other. Methods
Externí odkaz:
https://doaj.org/article/f2bc79ae35be430a9afb4d75ad0ce6bf
Publikováno v:
International Journal of Endorsing Health Science Research, Vol 12, Iss 1, Pp 30-38 (2023)
Abstract Background: Leukemia is a type of cancer that originates from the bone marrow's blood-forming stem cells. Cancer cells don't follow the usual cellular differentiation and function pathway, so they supersede the healthy cells. Depending on t
Externí odkaz:
https://doaj.org/article/1fbd4e4fe6e94199a2a400884fd7b0a0
Publikováno v:
Cells, Vol 13, Iss 12, p 1071 (2024)
Cancer accounted for 10 million deaths in 2020, nearly one in every six deaths annually. Despite advancements, the contemporary clinical management of human neoplasms faces a number of challenges. Surgical removal of tumor tissues is often not possib
Externí odkaz:
https://doaj.org/article/683c0799b7544c6d9a51d74ce92089ea
Autor:
Federica Nicolini, Toni Todorovski, Eduard Puig, Mireia Díaz-Lobo, Marta Vilaseca, Jesús García, David Andreu, Ernest Giralt
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 6, Pp 4985-5004 (2023)
Tumour suppressor p53 plays a key role in the development of cancer and has therefore been widely studied in recent decades. While it is well known that p53 is biologically active as a tetramer, the tetramerisation mechanism is still not completely u
Externí odkaz:
https://doaj.org/article/f44ed63b83854cd8b170cb02e58d2cf5
Publikováno v:
Asian Pacific Journal of Cancer Biology, Vol 8, Iss 1, Pp 69-73 (2023)
Genetic alterations are one of the important known risk factors of Prostate cancer. The family predisposition of breast and ovarian cancers may cause the lethal progression of familial prostate cancer in some men. The Association of germline mutation
Externí odkaz:
https://doaj.org/article/815b7eccfaca4a0ba9a3f5ce19245df2
Autor:
Sudarshan R Iyer, Kevin Nusser, Kristen Jones, Pushkar Shinde, Clare Keddy, Catherine Z Beach, Erin Aguero, Jeremy Force, Ujwal Shinde, Monika A Davare
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Abstract ROS1 is the largest receptor tyrosine kinase in the human genome. Rearrangements of the ROS1 gene result in oncogenic ROS1 kinase fusion proteins that are currently the only validated biomarkers for targeted therapy with ROS1 TKIs in patient
Externí odkaz:
https://doaj.org/article/808793d75f2f413c9604e051833dd047
Publikováno v:
Molecular & Cellular Oncology, Vol 9, Iss 1 (2022)
Genome sequenced samples from cancer patients helped identify roles of different mutation types and enabled targeted therapy development. However, critical questions like what are the gene mutation rates among the patients? or what genes are most com
Externí odkaz:
https://doaj.org/article/b851a127b3d54de68181f6bb07978732
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.