Zobrazeno 1 - 10
of 6 933
pro vyhledávání: '"cancer metabolism"'
Autor:
Francesco Gatto, Sinisa Bratulic, Francesca Maccari, Fabio Galeotti, Nicola Volpi, Jens Nielsen, Yair Lotan, Henrik Kjölhede
Publikováno v:
European Urology Open Science, Vol 68, Iss , Pp 40-47 (2024)
Background and objective: Screening for bladder cancer (BCa) could reduce mortality via early detection of early-stage high-grade (Ta/T1 N0 M0 grade 2–3) disease. Noninvasive biomarkers could aid in screening, but current markers lack the specifici
Externí odkaz:
https://doaj.org/article/ea6532441b704085861bdd4e804a3f8e
Autor:
Jing Wang, He-Kang Ding, Han-Jiang Xu, De-Kai Hu, William Hankey, Li Chen, Jun Xiao, Chao-Zhao Liang, Bing Zhao, Ling-Fan Xu
Publikováno v:
Asian Journal of Andrology, Vol 26, Iss 5, Pp 451-463 (2024)
Tumor metabolic reprogramming is a hallmark of cancer development, and targeting metabolic vulnerabilities has been proven to be an effective approach for castration-resistant prostate cancer (CRPC) treatment. Nevertheless, treatment failure inevitab
Externí odkaz:
https://doaj.org/article/460fbeac57cf4d20964db8f66e364717
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-40 (2024)
Abstract Cancer cells undergo significant metabolic reprogramming to support their rapid growth and survival. This study examines important metabolic pathways like glycolysis, oxidative phosphorylation, glutaminolysis, and lipid metabolism, focusing
Externí odkaz:
https://doaj.org/article/0f46445dc1cf4dd8a3e82f8ed5282fee
Autor:
Xi Hu, Daishun Ling
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4619-4621 (2024)
Externí odkaz:
https://doaj.org/article/250a63c16b1a4c2eae9c6639ed344642
Publikováno v:
Molecular Oncology, Vol 18, Iss 7, Pp 1739-1758 (2024)
Macrophages are innate immune cells that play key roles during both homeostasis and disease. Depending on the microenvironmental cues sensed in different tissues, macrophages are known to acquire specific phenotypes and exhibit unique features that,
Externí odkaz:
https://doaj.org/article/102a7d6cbe1d40af8d442682b439fc17
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1378-1396 (2024)
Ferroptosis is a newly identified iron‐dependent type of regulated cell death that can also be regarded as death caused by the specific collapse of the lipid antioxidant defence machinery. Ferroptosis has gained increasing attention as a potential
Externí odkaz:
https://doaj.org/article/38f7163513404f828b66e741db4d1b13
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-10 (2024)
Abstract KDM6A (lysine demethylase 6A) has been reported to undergo inactivating mutations in colorectal cancer, but its function in the progression of colorectal cancer has not been evaluated using animal models of colorectal cancer. In this study,
Externí odkaz:
https://doaj.org/article/55c3588e907546f2a7d869c55e20d6d3
Autor:
Boris Jakopovic, Anita Horvatić, Jurica Baranasic, Iris Car, Nada Oršolić, Ivan Jakopovich, Mirela Sedić, Sandra Kraljević Pavelić
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionColorectal cancer ranks as the third most common cancer in both men and women, with approximately 35% of cases being stage IV metastatic at diagnosis. Even with treatment advancements, the survival rates for these patients remain suboptim
Externí odkaz:
https://doaj.org/article/dba099ea96ef45d3a2509691beb48abd
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The genesis and progression of tumors are multifaceted processes influenced by genetic mutations within the tumor cells and the dynamic interplay with their surrounding milieu, which incessantly impacts the course of cancer. The tumor microenvironmen
Externí odkaz:
https://doaj.org/article/d29d6a0b1c1d40a890c6f12c4b17e9bd
Autor:
Zafer Gurel, Michael S. Luy, Qianyun Luo, Nicholas L. Arp, Amy K. Erbe, Aparna H. Kesarwala, Jing Fan, Randall J. Kimple
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionLactate is a pivotal molecule with diverse functions in the metabolic reprogramming of cancer cells. Beyond its role in metabolism, lactate exerts a modulatory effect within the tumor microenvironment; it is utilized by stromal cells and
Externí odkaz:
https://doaj.org/article/e11c06729ad144b8b224cd5c1aa245f1