Zobrazeno 1 - 10
of 6 001
pro vyhledávání: '"cancer development"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The morbidity and mortality rates of prostate cancer (PCa) are high among elderly men worldwide. Several factors, such as heredity, obesity, and environment are associated with the occurrence of PCa. Cigarette smoking, which is also an impor
Externí odkaz:
https://doaj.org/article/2b675e0042464c08ab29bb07530179f0
Autor:
Zequn Zheng, Yongfei Song
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Disulfidptosis, a newly identified form of regulated cell death associated with disruption of disulfide bond formation in the endoplasmic reticulum, involves the dysregulation of disulfidptosis-related genes (DRGs) that may contribute to can
Externí odkaz:
https://doaj.org/article/9c0f95a82a1b4625b4b011dbdf241809
Publikováno v:
Cancer Biology & Medicine, Vol 21, Iss 10, Pp 880-897 (2024)
Ubiquitination, a multifaceted post-translational modification, regulates protein function, degradation, and gene expression. The pivotal role of ubiquitination in the pathogenesis and progression of cancer, including colorectal, breast, and liver ca
Externí odkaz:
https://doaj.org/article/cbf0bace82fc46d98678ad1f052d2a31
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Copper (Cu) is used as a cofactor in all organisms, and yet it can be toxic at high intracellular concentrations, causing cell death. Diethyldithiocarbamate (DDC) is a Cu ionophore that can transport Cu effectively into the cell. Copper-diet
Externí odkaz:
https://doaj.org/article/0c5fe8a60e204cda86d41b97315b43b0
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Prostate cancer (PCa) is a commonly occurring malignancy in elderly men. Olaparib, a poly ADP-ribose polymerase inhibitor, is utilized in PCa treatment. However, patients often develop resistance to olaparib after a period of treatment. Gene
Externí odkaz:
https://doaj.org/article/7f615adb8c2a44f29c8a4b128e6aebd9
Autor:
Wen-Jing Liu, Lin Wang, Fan-Li Sun, Feng-Mei Zhou, Rui-Ke Zhang, Jie Liu, Min Zhao, Li-Hong Wang, Yan-Ru Qin, Yan-Qiu Zhao, Jian-Ge Qiu, Bing-Hua Jiang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 288, Iss , Pp 117341- (2024)
Lung cancer is the leading factor of cancer-related death in the worldwide. Hexavalent chromium [Cr(VI)] is a potential carcinogen for inducing lung cancers. To understand new mechanism of Cr(VI)-induced tumorigenesis and cancer development, we ident
Externí odkaz:
https://doaj.org/article/114dfb3c116e41acadfd811b281b02fc
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTThe role of gut fungal species in tumor-related processes remains largely unexplored, with most studies still focusing on fungal infections. This review examines the accumulating evidence suggesting the involvement of commensal and pathogenic
Externí odkaz:
https://doaj.org/article/c79f604e8a7d4c9091e1b27b2bd7051f
Autor:
Zixu Zhang, David Westover, Zhantong Tang, Yue Liu, Jinghan Sun, Yunxi Sun, Runqing Zhang, Xingyue Wang, Shihui Zhou, Nigaerayi Hesilaiti, Qi Xia, Zhenfang Du
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-26 (2024)
Abstract Wnt/β-catenin signaling is a critical pathway that influences development and therapeutic response of non-small cell lung cancer (NSCLC). In recent years, many Wnt regulators, including proteins, miRNAs, lncRNAs, and circRNAs, have been fou
Externí odkaz:
https://doaj.org/article/4ed9d1047bf4444f8b031273f0e24e68
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Castration-resistant prostate cancer (CRPC) represents the final stage of prostate cancer (PCa). Cabazitaxel, a taxane chemotherapy drug, is used in treating CRPC. However, patients with CRPC eventually develop resistance to cabazitaxel, and
Externí odkaz:
https://doaj.org/article/7d1117980af84257be763aff6bbcbcf5
Autor:
Shanika Karunasagara, Ali Taghizadeh, Sang‐Hyun Kim, So Jung Kim, Yong‐Jae Kim, Mohsen Taghizadeh, Moon‐Young Kim, Kyu‐Young Oh, Jung‐Hwan Lee, Hye Sung Kim, Jeongeun Hyun, Hae‐Won Kim
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Epithelial‐stromal interplay through chemomechanical cues from cells and matrix propels cancer progression. Elevated tissue stiffness in potentially malignant tissues suggests a link between matrix stiffness and enhanced tumor growth. In t
Externí odkaz:
https://doaj.org/article/5d9ed89cb8184bc5be14e2bdcc15a4b7