Zobrazeno 1 - 10
of 73
pro vyhledávání: '"cancer cell of origin"'
Autor:
Helge Waldum, Geir Slupphaug
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Malignancy manifests itself by deregulated growth and the ability to invade surrounding tissues or metastasize to other organs. These properties are due to genetic and/or epigenetic changes, most often mutations. Many aspects of carcinogenesis are kn
Externí odkaz:
https://doaj.org/article/041b208cc64b43449737c4d2e97884e7
Autor:
Singh, Hardeep P., Wang, Sijia, Stachelek, Kevin, Lee, Sunhye, Reid, Mark W., Thornton, Matthew E., Craft, Cheryl Mae, Grubbs, Brendan H., Cobrinik, David
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Oct 01. 115(40), E9391-E9400.
Externí odkaz:
https://www.jstor.org/stable/26531422
Autor:
Anhao Tian, Bo Kang, Baizhou Li, Biying Qiu, Wenhong Jiang, Fangjie Shao, Qingqing Gao, Rui Liu, Chengwei Cai, Rui Jing, Wei Wang, Pengxiang Chen, Qinghui Liang, Lili Bao, Jianghong Man, Yan Wang, Yu Shi, Jin Li, Minmin Yang, Lisha Wang, Jianmin Zhang, Simon Hippenmeyer, Junming Zhu, Xiuwu Bian, Ying‐Jie Wang, Chong Liu
Publikováno v:
Advanced Science, Vol 7, Iss 21, Pp n/a-n/a (2020)
Abstract Glioblastoma is the most malignant cancer in the brain and currently incurable. It is urgent to identify effective targets for this lethal disease. Inhibition of such targets should suppress the growth of cancer cells and, ideally also preca
Externí odkaz:
https://doaj.org/article/baefe91ff8084838a59dc9ab8b900662
Autor:
Alexandra Van Keymeulen, Marco Fioramonti, Alessia Centonze, Gaëlle Bouvencourt, Younes Achouri, Cédric Blanpain
Publikováno v:
Cell Reports, Vol 20, Iss 7, Pp 1525-1532 (2017)
The mammary gland (MG) is composed of different cell lineages, including the basal and the luminal cells (LCs) that are maintained by distinct stem cell (SC) populations. LCs can be subdivided into estrogen receptor (ER)+ and ER− cells. LCs act as
Externí odkaz:
https://doaj.org/article/a77689ea24cd4235b4390791b29c36ee
Publikováno v:
Cell Reports, Vol 18, Iss 12, Pp 2825-2835 (2017)
Delineating the mammary differentiation hierarchy is important for the study of mammary gland development and tumorigenesis. Mammary luminal cells are considered a major origin of human breast cancers. However, how estrogen-receptor-positive (ER+) an
Externí odkaz:
https://doaj.org/article/1876e53bdc02400aba7fdacbc77c19cc
Autor:
Guillermo Rodríguez-Hernández, Sanil Bhatia, Carolina Vicente-Dueñas, Arndt Borkhardt, Julia Hauer, Isidro Sánchez-García
Publikováno v:
Molecular & Cellular Oncology, Vol 5, Iss 4 (2018)
Genetic lineage tracing in cell type-specific mouse models of T-cell acute lymphoblastic leukemia (T-ALL) have revealed that tumor cell identity is imposed by expression of the oncogene Lim Domain Only 2 (LMO2), rather than by the target cell phenoty
Externí odkaz:
https://doaj.org/article/e57e34ff38b6422881995b7b42a3f771
Akademický článek
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Akademický článek
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Kniha
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Autor:
Chong Liu, Jin Li, Simon Hippenmeyer, Baizhou Li, Wenhong Jiang, Yan Wang, Wei Wang, Jianmin Zhang, Qingqing Gao, Pengxiang Chen, Minmin Yang, Qinghui Liang, Rui Liu, Lisha Wang, Rui Jing, Lili Bao, Biying Qiu, Yu Shi, Chengwei Cai, Xiu-Wu Bian, Ying-Jie Wang, Junming Zhu, Jianghong Man, Fangjie Shao, Bo Kang, Anhao Tian
Publikováno v:
Advanced Science
Advanced Science, Vol 7, Iss 21, Pp n/a-n/a (2020)
Advanced Science, Vol 7, Iss 21, Pp n/a-n/a (2020)
Glioblastoma is the most malignant cancer in the brain and currently incurable. It is urgent to identify effective targets for this lethal disease. Inhibition of such targets should suppress the growth of cancer cells and, ideally also precancerous c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7727a143c543d8c4800c2adbb2c91da0
http://europepmc.org/articles/PMC7610337
http://europepmc.org/articles/PMC7610337