Zobrazeno 1 - 10
of 2 518
pro vyhledávání: '"cancer/testis antigens"'
Autor:
Tsima Abou Kors, Matthias Meier, Lena Mühlenbruch, Annika C. Betzler, Franziska Oliveri, Martin Bens, Jaya Thomas, Johann M. Kraus, Johannes Doescher, Adrian von Witzleben, Linda Hofmann, Jasmin Ezic, Diana Huber, Julian Benckendorff, Thomas F. E. Barth, Jens Greve, Patrick J. Schuler, Cornelia Brunner, Jonathan M. Blackburn, Thomas K. Hoffmann, Christian Ottensmeier, Hans A. Kestler, Hans-Georg Rammensee, Juliane S. Walz, Simon Laban
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe human leukocyte antigen complex (HLA) is essential for inducing specific immune responses to cancer by presenting tumor-associated peptides (TAP) to T cells. Overexpressed tumor associated antigens, mainly cancer-testis antigens (CTA)
Externí odkaz:
https://doaj.org/article/395296b0c62b42a7af04bb14da175331
Autor:
Karla Cristina Tabosa Machado, Tayna da Silva Fiuza, Sandro Jose de Souza, Gustavo Antonio de Souza
Publikováno v:
IEEE Access, Vol 12, Pp 150930-150939 (2024)
Biomarkers are molecular markers found in clinical samples which may aid disease diagnosis or prognosis. High-throughput techniques allow prospecting for such signature molecules by comparing gene expression between normal and sick cells. Cancer-test
Externí odkaz:
https://doaj.org/article/49ad99d7ecb54a52b4a3844e144fae49
Autor:
Feria Hikmet, Marc Rassy, Max Backman, Loren Méar, Johanna Sofia Margareta Mattsson, Dijana Djureinovic, Johan Botling, Hans Brunnström, Patrick Micke, Cecilia Lindskog
Publikováno v:
Molecular Oncology, Vol 17, Iss 12, Pp 2603-2617 (2023)
The antigenic repertoire of tumors is critical for successful anti‐cancer immune response and the efficacy of immunotherapy. Cancer–testis antigens (CTAs) are targets of humoral and cellular immune reactions. We aimed to characterize CTA expressi
Externí odkaz:
https://doaj.org/article/d2dba137018343088d9db9aa33cbe23d
Autor:
Emmanuelle Jacquet, Florent Chuffart, Anne-Laure Vitte, Eleni Nika, Mireille Mousseau, Saadi Khochbin, Sophie Rousseaux, Ekaterina Bourova-Flin
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background In breast cancer, as in all cancers, genetic and epigenetic deregulations can result in out-of-context expressions of a set of normally silent tissue-specific genes. The activation of some of these genes in various cancers empower
Externí odkaz:
https://doaj.org/article/fd2e9ffeb3304249be739b30ae6687f3
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Digestive tract cancers, including esophageal, gastric, and colorectal cancers, are the major cause of death among cancer patients worldwide due to the heterogeneity of cancer cells, which limits the effectiveness of traditional treatment methods. Im
Externí odkaz:
https://doaj.org/article/87469c80f7ab40c8ae7be466ca3ab8b2
Autor:
Yingyu Xu, Xin Xu, Xiaojian Ni, Jiaomeng Pan, MaoPei Chen, Youpei Lin, Zhiying Zhao, Lan Zhang, Ningling Ge, Guohe Song, Juan Zhang
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e13269- (2023)
Cancer/testis antigens (CTAs) are reproductive tissue-restricted genes, frequently ectopic expressed in tumors. CTA genes associate with a poor prognosis in some solid tumors, due to their potential roles in the tumorigenesis and progression. However
Externí odkaz:
https://doaj.org/article/d39f1e1ef035452ea6f50f10c3abfd7a
Autor:
D. S. Kutilin, O. I. Kit
Publikováno v:
Сибирский онкологический журнал, Vol 21, Iss 1, Pp 37-46 (2022)
Introduction. High incidence and mortality rates of colorectal cancer indicate an urgent need for the use of new highly specific diagnostic and prognostic molecular markers. In this aspect, cancer testis antigens (CTA s) are of particular interest.Th
Externí odkaz:
https://doaj.org/article/0fa1ec4e499046dfa20b64e9ca70ea63
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1704 (2023)
Melanoma-associated antigen A (MAGEA) subfamily proteins are normally expressed in testis and/or placenta. However, aberrant expression is detected in the tumour cells of multiple types of human cancer. MAGEA expression is mainly observed in cancers
Externí odkaz:
https://doaj.org/article/2d49b944f788428c9a26ef4d10846638
Publikováno v:
Diagnostics, Vol 13, Iss 19, p 3092 (2023)
The main goal of this study was to characterize cancer/testis antigens (CTAs) as potential molecular markers of ovarian cancer. First, we gathered and analyzed a significantly large dataset of 21 selected CTAs that are encoded by 32 genes; the datase
Externí odkaz:
https://doaj.org/article/67c26db31c194425ae1d453b5f6dcb8e
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14679 (2023)
In the last few decades, RNA-based drugs have emerged as a promising candidate in the treatment of various diseases. The introduction of messenger RNA (mRNA) as a vaccine or therapeutic agent enables the production of almost any functional protein/pe
Externí odkaz:
https://doaj.org/article/722300b4343c46b4acc0e4f5d777f0ef