Zobrazeno 1 - 10
of 28
pro vyhledávání: '"canalicular secretion"'
Autor:
Xiulong Song, Yuan Chen, Leila Valanejad, Rajani Kaimal, Bingfang Yan, Matthew Stoner, Ruitang Deng
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 11, Pp 3030-3044 (2013)
Expression of bile salt export pump (BSEP) is regulated by the bile acid/farnesoid X receptor (FXR) signaling pathway. Two FXR isoforms, FXRα1 and FXRα2, are predominantly expressed in human liver. We previously showed that human BSEP was isoform-d
Externí odkaz:
https://doaj.org/article/321e3c8bcb46414897464549dea7ea3e
Autor:
Barth, C. A., Schwarz, L. R.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1982 Aug . 79(16), 4985-4987.
Externí odkaz:
https://www.jstor.org/stable/12651
Autor:
Alain Moreau, Peter L. M. Jansen, Edith Rogier, Gérard Feldmann, Corinne D'Hont, Serge Erlinger, M. Dumont
Publikováno v:
Liver, 16(1), 35-41
Liver, 16(1), 35-41. Wiley-Blackwell
Liver, 16(1), 35-41. Wiley-Blackwell
Diethylmaleate is an organic anion secreted into bile as a glutathione conjugate. Its transport by the hepatocyte is associated with dilatation of the Golgi apparatus and the appearance of small vesicles in the pericanalicular area. It has been specu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5625844662da3d17a0f7405883919ea7
https://doi.org/10.1111/j.1600-0676.1996.tb00701.x
https://doi.org/10.1111/j.1600-0676.1996.tb00701.x
Publikováno v:
Toxicology in Vitro
Toxicology in Vitro, 2015, 29 (5), pp.938-946. ⟨10.1016/j.tiv.2015.03.019⟩
Toxicology in Vitro, Elsevier, 2015, 29 (5), pp.938-946. ⟨10.1016/j.tiv.2015.03.019⟩
Toxicology in Vitro, 2015, 29 (5), pp.938-946. ⟨10.1016/j.tiv.2015.03.019⟩
Toxicology in Vitro, Elsevier, 2015, 29 (5), pp.938-946. ⟨10.1016/j.tiv.2015.03.019⟩
International audience; Human hepatocytes cultured in a monolayer configuration represent a well-established in vitro model in liver toxicology, notably used in drug transporter studies. Polarized status of drug transporters, i.e., their coordinated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c3a4cd5750d9bf635b19dff342fa77
https://univ-rennes.hal.science/hal-01141725
https://univ-rennes.hal.science/hal-01141725
Publikováno v:
Journal of Hepatology. 31(4):678-684
Background/Aims: Fluorescent bile acids have proved useful for characterizing bile salt transport mechanisms, The aim of this study was to further validate the use of lysyl-fluorescein conjugated bile acid analogues as surrogate bile acids, Methods:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::8d3d9ec3a63c7a1b63bb65c66a3d6681
https://hdl.handle.net/11370/03258a7e-a41d-41e8-8a18-27e05d64c471
https://hdl.handle.net/11370/03258a7e-a41d-41e8-8a18-27e05d64c471
Autor:
Elwyn Elias, Folkert Kuipers, Piotr Milkiewicz, Michael Müller, Rick Havinga, Roger Coleman, Peter L.M. Jansen, Charles O. Mills, Marcelo G. Roma
Publikováno v:
Journal of hepatology, 31(4), 678-684. Elsevier
Journal of Hepatology, 31(4), 678-684. ELSEVIER SCIENCE BV
Journal of Hepatology, 31(4), 678-684. ELSEVIER SCIENCE BV
Background/Aims: Fluorescent bile acids have proved useful for characterizing bile salt transport mechanisms. The aim of this study was to further validate the use of lysyl-fluorescein conjugated bile acid analogues as surrogate bile acids. Methods:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67809de050cd5a6d0a511223134df2ed
https://doi.org/10.1016/s0168-8278(99)80348-1
https://doi.org/10.1016/s0168-8278(99)80348-1
Publikováno v:
Liver. 16(1):35-41
Diethylmaleate is an organic anion secreted into bile as a glutathione conjugate. Its transport by the hepatocyte is associated with dilatation of the Golgi apparatus and the appearance of small vesicles in the pericanalicular area. It has been specu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::34807381ed9d853ab92acee63785a7a3
https://hdl.handle.net/11370/f669be1e-df88-4181-a48a-cb33fca6f2b6
https://hdl.handle.net/11370/f669be1e-df88-4181-a48a-cb33fca6f2b6
Autor:
Domenico Ferri, Piero Portincasa, Raúl A. Marinelli, Giuliano Meyer, Maria Svelto, Patrizia Gena, Giuseppe Calamita, Giuseppa Esterina Liquori
Formation of bile and generation of bile flow are driven by the active secretion of bile salts (BS), lipids and electrolytes into the canalicular and bile duct lumens followed by the osmotic movement of water. Although the transporting proteins invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc18e4464fc04c156adcf9f36fb354a1
http://hdl.handle.net/2434/14263
http://hdl.handle.net/2434/14263
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