Reduced exploratory behavior in neuronal nucleoredoxin knockout mice

Autor: Bao Ngoc Tran, Lucie Valek, Annett Wilken-Schmitz, Dominik Christian Fuhrmann, Dimitry Namgaladze, Ilka Wittig, Irmgard Tegeder

Publikováno v: Redox Biology, Vol 45, Iss , Pp 102054- (2021)

Nucleoredoxin is a thioredoxin-like redoxin that has been recognized as redox modulator of WNT signaling. Using a Yeast-2-Hybrid screen, we identified calcium calmodulin kinase 2a, Camk2a, as a prominent prey in a brain library. Camk2a is crucial for

Externí odkaz: https://doaj.org/article/bfa50570eabc4019b5ac0b9f650d83b1

Calcium/Calmodulin Kinase IV Controls the Function of Both T Cells and Kidney Resident Cells

Autor: Andrew P. Ferretti, Rhea Bhargava, Shani Dahan, Maria G. Tsokos, George C. Tsokos

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Calcium calmodulin kinase IV (CaMK4) regulates multiple processes that significantly contribute to the lupus-related pathology by controlling the production of IL-2 and IL-17 by T cells, the proliferation of mesangial cells, and the function and stru

Externí odkaz: https://doaj.org/article/6f9f365f46ec480d84830d26f806a6c1

Reduced exploratory behavior in neuronal nucleoredoxin knockout mice

Autor: Tran, Bao Ngoc, Valek, Lucie, Wilken-Schmitz, Annett, Fuhrmann, Dominik Christian, Namgaladze, Dimitry, Wittig, Ilka, Tegeder, Irmgard

Publikováno v: Redox Biology
Redox Biology, Vol 45, Iss, Pp 102054-(2021)

Nucleoredoxin is a thioredoxin-like redoxin that has been recognized as redox modulator of WNT signaling. Using a Yeast-2-Hybrid screen, we identified calcium calmodulin kinase 2a, Camk2a, as a prominent prey in a brain library. Camk2a is crucial for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ed956c8a59a7a80f2be9c373fa9c175e
http://europepmc.org/articles/PMC8254043

Protein Phosphorylation in Depolarized Synaptosomes: Dissecting Primary Effects of Calcium from Synaptic Vesicle Cycling

Autor: Ivan Silbern, Henning Urlaub, Reinhard Jahn, Kuan-Ting Pan, Stefan Bonn, Maksims Fiosins, Silvio O. Rizzoli, Eugenio F. Fornasiero

Publikováno v: Molecular & Cellular Proteomics : MCP
Molecular and Cellular Proteomics
Molecular & cellular proteomics 20, 100061-(2021). doi:10.1016/j.mcpro.2021.100061

Synaptic transmission is mediated by the regulated exocytosis of synaptic vesicles. When the presynaptic membrane is depolarized by an incoming action potential, voltage-gated calcium channels open, resulting in the influx of calcium ions that trigge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d93635b9e859a1023882c0903a6342
https://pubmed.ncbi.nlm.nih.gov/33582301

A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy

Autor: Ekaterina Mokhonova, April D. Pyle, Irina Kramerova, Melissa J. Spencer, Varghese John, Robert Damoiseaux, Huan Meng, Diana Becerra, Jesus Campagna, Elizabeth M. McNally, Jian Liu

Publikováno v: Cell reports. Medicine, vol 1, iss 7
Cell Reports Medicine
Cell Reports Medicine, Vol 1, Iss 7, Pp 100122-(2020)

Summary Mutations in CAPN3 cause limb girdle muscular dystrophy R1 (LGMDR1, formerly LGMD2A) and lead to progressive and debilitating muscle wasting. Calpain 3 deficiency is associated with impaired CaMKIIβ signaling and blunted transcriptional prog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3d86417df5255a7191e36f55ce802a
https://escholarship.org/uc/item/42j9r8tc