Zobrazeno 1 - 10
of 83
pro vyhledávání: '"calcific aortic valve disease (CAVD)"'
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31871- (2024)
Background: Transient receptor potential melastatin 4 (TRPM4) affects immune responses by regulating calcium homeostasis, but its role in calcific aortic valve inflammation remains unclear. This study aimed to assess the expression and function of TR
Externí odkaz:
https://doaj.org/article/c53e198d94f64ef1880248245f287642
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Calcific aortic valve disease (CAVD) is characterized by progressive stiffening of aortic valve (AV) tissues, inducing stenosis and insufficiency. Bicuspid aortic valve (BAV) is a common congenital defect in which the AV has two leaflets rather than
Externí odkaz:
https://doaj.org/article/0902442305f54c9d8313db48197dffc1
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Human aortic valve interstitial cells (hAVICs) are a key factor in the pathogenesis of calcific aortic valve disease (CAVD). This research examines the role and mechanism of microRNA miR-138-5p in osteogenic differentiation of hAV
Externí odkaz:
https://doaj.org/article/f0866dfb20a540fcaad44cebd50df8f1
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Over the years, bioinformatics tools have been used to identify functional genes. In the present study, bioinformatics analyses were conducted to explore the underlying molecular mechanisms of angiogenic factors in calcific aortic valve disease (CAVD
Externí odkaz:
https://doaj.org/article/4deb3f70e53940a5a376520c27551db4
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2023)
BackgroundCAVD is a common cardiovascular disease, but currently there is no drug treatment. Therefore, it is urgent to find new and effective drug therapeutic targets. Recent evidence has shown that the infiltration of M1 macrophages increased in th
Externí odkaz:
https://doaj.org/article/e2edd1f4ce1e407fb00bb0349e72d47f
Autor:
Jessica I. Selig, H. Viviana Krug, Caroline Küppers, D. Margriet Ouwens, Felix A. Kraft, Elena Adler, Sebastian J. Bauer, Artur Lichtenberg, Payam Akhyari, Mareike Barth
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Diabetes and its major key determinants insulin resistance and hyperglycemia are known risk factors for calcific aortic valve disease (CAVD). The processes leading to molecular and structural alterations of the aortic valve are yet not fully understo
Externí odkaz:
https://doaj.org/article/952065509df84226b5fa55f606829115
Akademický článek
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Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Calcific aortic valve disease (CAVD) is a common acquired valvulopathy, which carries a high burden of mortality. Chronic inflammation has been postulated as the predominant pathophysiological process underlying CAVD. So far, no effective medical the
Externí odkaz:
https://doaj.org/article/3de46a837ac44fcca4f313f9e3f09c78
Autor:
Giacomo Bernava, Enrico Fermi, Guido Gelpi, Stefano Rizzi, Davide Benettin, Marianna Barbuto, Claudia Romagnoni, Domenico Ventrella, Maria Chiara Palmieri, Marco Agrifoglio, Gianluca Polvani, Maria Laura Bacci, Enrico Pasquino, Maurizio Pesce
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
The increasing incidence of calcific aortic valve disease necessitates the elaboration of new strategies to retard the progression of the pathology with an innovative solution. While the increasing diffusion of the transcatheter aortic valve replacem
Externí odkaz:
https://doaj.org/article/c4c620131bea414da7c4d74bba41ed54
Autor:
Silvia Ferrari, Maurizio Pesce
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Calcification of the aortic valve is one of the most rapidly increasing pathologies in the aging population worldwide. Traditionally associated to cardiovascular risk conditions, this pathology is still relatively unaddressed on a molecular/cellular
Externí odkaz:
https://doaj.org/article/29fe2d62e14d4857bea8f15eae19833c