Zobrazeno 1 - 10
of 8 343
pro vyhledávání: '"caga"'
Autor:
Hui-Jen Tsai, Kun-Huei Yeh, Chung-Wu Lin, Ming-Shiang Wu, Jyh-Ming Liou, Ping-Ning Hsu, Yi-Shin Zeng, Ming-Feng Wei, Chia-Tung Shun, Hsiu-Po Wang, Li-Tzong Chen, Ann-Lii Cheng, Sung-Hsin Kuo
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background This study aimed to explore whether cytotoxin-associated gene A (CagA) can inhibit cell cycle progression by activating nuclear factor of activated T cells (NFAT) in lymphoma B cells and contribute to Helicobacter pylori eradicati
Externí odkaz:
https://doaj.org/article/1bfa83ead9da49a49665bdaad9c5b49e
Autor:
Xiaofei Ji, Zekun Sun, Hao Wu, Jianhui Zhang, Shuzhen Liu, Xinying Cao, Bin Wang, Feifan Wang, Ying Zhang, Boqing Li, Jiankai Feng, Huilin Zhao
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Chronic infection by Helicobacter pylori strains expressing cytotoxin-associated gene A (CagA) are the strongest risk factor for gastric cancer. CagA can be classified into East Asian-type and Western-type (CagAE and CagAW), with
Externí odkaz:
https://doaj.org/article/05d889b34d274f31a5631bc71ceb05f9
Autor:
Huiling Zheng, Ting Zhang, Jing Zhang, Jing Ning, Weiwei Fu, Ye Wang, Yanyan Shi, Guochao Wei, Xiangmei Chen, Shigang Ding
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
CagA, a virulence factor of Helicobacter pylori (H. pylori), is known to drive inflammation in gastric epithelial cells and is typically degraded through autophagy. However, the molecular mechanism by which CagA evades autophagy-mediated degradation
Externí odkaz:
https://doaj.org/article/e00b7ed5333d4bdcb1bce7670c8f0e08
Autor:
Xiaofei Ji, Qianwen Wu, Xinying Cao, Shuzhen Liu, Jianhui Zhang, Si Chen, Jiangfan Shan, Ying Zhang, Boqing Li, Huilin Zhao
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
CagA is a significant oncogenic factor injected into host cells by Helicobacter pylori, which is divided into two subtypes: East Asian type (CagAE), characterized by the EPIYA-D motif, and western type (CagAW), harboring the EPIYA-C motif. CagAE has
Externí odkaz:
https://doaj.org/article/2f06a07091894a5ba6dd996bef117de8
Autor:
Facundo Maiorana, Magali Neschuk, María Virginia Caronia, Karina Elizondo, Adolfo Schneider, Georgina Veron, Pedro D Zapata, Fernando Javier Barreyro
Publikováno v:
Annals of Hepatology, Vol 29, Iss 6, Pp 101541- (2024)
Introduction and Objectives: Recent studies have suggested an association between H. pylori and metabolic dysfunction associated steatotic liver disease (MASLD). We aim to evaluate the association of H. pylori virulence genes with non-invasive marker
Externí odkaz:
https://doaj.org/article/da5ceb26a00e4d3cb971e53914c8af0a
Publikováno v:
Biomedical and Biotechnology Research Journal, Vol 8, Iss 2, Pp 243-250 (2024)
Background: The relationship between gastroesophageal reflux disease (GERD) and Helicobacter pylori infection is a complicated topic. This study aimed to evaluate the association between H. pylori infection and GERD and identify the associated risk f
Externí odkaz:
https://doaj.org/article/209958e6b4be498a9bd92aeaf06236c1
Autor:
Mutita Wongsuwanlert, Rawee Teanpaisan, Nuntiya Pahumunto, Apichat Kaewdech, Praphansri Ruangsri, Somkiat Sunpaweravong
Publikováno v:
Journal of Dental Sciences, Vol 19, Iss 2, Pp 1036-1043 (2024)
Background/purpose: The oral cavity is considered a reservoir of Helicobacter pylori associated with gastric infection. It aimed to examine the prevalence of H. pylori strains from the oral cavity and gastric tissue of patients with different stage o
Externí odkaz:
https://doaj.org/article/985388fb40b948e98f821797d8924c05
Autor:
Ritwik Maity, Xuepei Zhang, Francesca Romana Liberati, Chiara Scribani Rossi, Francesca Cutruzzolá, Serena Rinaldo, Massimiliano Gaetani, José Antonio Aínsa, Javier Sancho
Publikováno v:
eLife, Vol 13 (2024)
Antimicrobial resistance is responsible for an alarming number of deaths, estimated at 5 million per year. To combat priority pathogens, like Helicobacter pylori, the development of novel therapies is of utmost importance. Understanding the molecular
Externí odkaz:
https://doaj.org/article/8e9d33b85838437486c00c392fcb85a6
GRB7-mediated enhancement of cell malignant characteristics induced by Helicobacter pylori infection
Autor:
Huilin Zhao, Si Chen, Xinfeng Bai, Jianhui Zhang, Shuzhen Liu, Zekun Sun, Xinying Cao, Jianping Wang, Ying Zhang, Boqing Li, Xiaofei Ji
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Growth factor receptor bound protein 7 (GRB7) is reportedly upregulated in human gastric cancer (GC), which is closely associated with tumor progression and prognosis. However, the mechanism underlying its dysregulation in GC remains poorly understoo
Externí odkaz:
https://doaj.org/article/110cfd7211cd4fb383eb27eaa63c888c
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background Helicobacter pylori (H. pylori), according to a number of recent observational studies, is connected to atherosclerosis (AS). However, the link between H. pylori and AS is debatable. Methods In order to calculate the causal relati
Externí odkaz:
https://doaj.org/article/d53d5c6516ea4c9d9a91a301c8b0672d