Zobrazeno 1 - 10
of 838
pro vyhledávání: '"ca2+ transients"'
Autor:
Yangpeng Li, Zhu Liu, Christopher O'Shea, Jianhong Li, Xian Luo, Tangting Chen, Xianhong Ou, Weichao Liu, Guoliang Hao, Christopher L.-H. Huang, Davor Pavlovic, Xiaoqiu Tan, Ming Lei
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 10, Iss , Pp 100121- (2024)
Abnormal regional variations in electrical and calcium homeostasis properties have been implicated in catecholaminergic polymorphic ventricular tachycardias (CPVT) attributable to abnormal RyR2-mediated store Ca2+ release, but their underlying mechan
Externí odkaz:
https://doaj.org/article/d95071de13a6439aa56060917c1c512a
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundProtein phosphatase 2A (PP2A) is a serine/threonine-selective holoenzyme that controls Ca2+ homeostasis and contractility of the heart via dephosphorylation of regulatory proteins. In some genetically modified mouse models with increased ar
Externí odkaz:
https://doaj.org/article/80ffa131add3420da5a8e722ef4dfdbc
Akademický článek
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Akademický článek
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Autor:
Joshua Barry, Katerina D. Oikonomou, Allison Peng, Daniel Yu, Chenyi Yang, Peyman Golshani, Christopher J. Evans, Michael S. Levine, Carlos Cepeda
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
Opioids are the most common medications for moderate to severe pain. Unfortunately, they also have addictive properties that have precipitated opioid misuse and the opioid epidemic. In the present study, we examined the effects of acute administratio
Externí odkaz:
https://doaj.org/article/f3c1a56a3b2a46759a146183625a03d0
Autor:
Fusheng Ding, Shanshan Liang, Ruijie Li, Zhiqi Yang, Yong He, Shaofan Yang, Qingtian Duan, Jianxiong Zhang, Jing Lyu, Zhenqiao Zhou, Mingzhu Huang, Haoyu Wang, Jin Li, Chuanyan Yang, Yuxia Wang, Mingyue Gong, Shangbin Chen, Hongbo Jia, Xiaowei Chen, Xiang Liao, Ling Fu, Kuan Zhang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Astrocytic Ca2+ transients are essential for astrocyte integration into neural circuits. These Ca2+ transients are primarily sequestered in subcellular domains, including primary branches, branchlets and leaflets, and endfeet. In previous studies, it
Externí odkaz:
https://doaj.org/article/3ac07154c12645a4a38f5a9c6aa2150e
Autor:
Lina T Al Kury, Vadym Sydorenko, Manal MA Smail, Muhammad A Qureshi, Anatoly Shmygol, Dimitrios Papandreou, Jaipaul Singh, Frank Christopher Howarth
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 4, Pp 493-500 (2021)
Abstract Aims/Introduction Abnormalities in Ca2+ signaling have a key role in hemodynamic dysfunction in diabetic heart. The purpose of this study was to explore the effects of streptozotocin (STZ)‐induced diabetes on Ca2+ signaling in epicardial (
Externí odkaz:
https://doaj.org/article/5b51b840e09d48c3bccfa5adb5f30ca7
Akademický článek
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Autor:
Junlan Zhou, Neha Singh, Chloe Monnier, William Marszalec, Li Gao, Jing Jin, Michael Frisk, William E. Louch, Suresh Verma, Prasanna Krishnamurthy, Elsa Nico, Maaz Mulla, Gary L. Aistrup, Raj Kishore, J. Andrew Wasserstrom
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
BIN1 (amphyphysin-II) is a structural protein involved in T-tubule (TT) formation and phosphatidylinositol-4,5-bisphosphate (PIP2) is responsible for localization of BIN1 to sarcolemma. The goal of this study was to determine if PIP2-mediated targeti
Externí odkaz:
https://doaj.org/article/6d65aa37066c4ce8a35e0b34b74789aa
Publikováno v:
BMC Anesthesiology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background The potential mechanism of mepivacaine’s myocardial depressant effect observed in papillary muscle has not yet been investigated at cellular level. Therefore, we evaluated mepivacaine’s effects on Ca2+ transient in isolated ad
Externí odkaz:
https://doaj.org/article/9721caeda65040709d0f39e844ec02cf