Zobrazeno 1 - 10
of 608
pro vyhledávání: '"cPLA2"'
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 7, Pp 100571- (2024)
Phospholipase A2 (PLA2) constitutes a superfamily of enzymes that hydrolyze phospholipids at their sn-2 fatty acyl position. Our laboratory has demonstrated that PLA2 enzymes regulate membrane remodeling and cell signaling by their specificity toward
Externí odkaz:
https://doaj.org/article/f01e89ee556e4921a995e0e6e7bc2196
Autor:
Yi Chang, Chih-Wei Hsia, Kuan-Rau Chiou, Ting-Lin Yen, Thanasekaran Jayakumar, Joen-Rong Sheu, Wei-Chieh Huang
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1689 (2024)
Background: Platelets, a type of anucleated cell, play a crucial role in cardiovascular diseases (CVDs). Therefore, targeting platelet activation is essential for mitigating CVDs. Endogenous agonists, such as collagen, activate platelets by initiatin
Externí odkaz:
https://doaj.org/article/09453405393b47ec91b21a9f5a1f9e29
Autor:
Ivanna Carolina Golfetto Miskiewicz, Hyen Chung Cho, Ji In Lee, Jihye Lee, Yenna Lee, Yun Kyung Lee, Sung Hee Choi
Publikováno v:
FEBS Open Bio, Vol 13, Iss 4, Pp 606-616 (2023)
Lipid accumulation in hepatocytes can result from an imbalance between lipid acquisition and lipid catabolism. In recent years, it has been discovered that eicosanoids derived from arachidonic acid (AA) have the potential to create specialized pro‐
Externí odkaz:
https://doaj.org/article/2c3a110ce4124b398516242f1fc61ace
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Shaowei Wang, Boyang Li, Victoria Solomon, Alfred Fonteh, Stanley I. Rapoport, David A. Bennett, Zoe Arvanitakis, Helena C. Chui, Patrick M. Sullivan, Hussein N. Yassine
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-21 (2022)
Abstract Background Apolipoprotein E4 (APOE4) is associated with a greater response to neuroinflammation and the risk of developing late-onset Alzheimer’s disease (AD), but the mechanisms for this association are not clear. The activation of calciu
Externí odkaz:
https://doaj.org/article/9b6fcfbf82ae45668070da91de7eda75
Autor:
Sanjay Mishra, Manish Charan, Rajni Kant Shukla, Pranay Agarwal, Swati Misri, Ajeet K. Verma, Dinesh K. Ahirwar, Jalal Siddiqui, Kirti Kaul, Neety Sahu, Kunj Vyas, Ayush Arpit Garg, Anum Khan, Wayne O. Miles, Jonathan W. Song, Nidhi Bhutani, Ramesh K. Ganju
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Molecular mechanisms underlying inflammation-associated breast tumor growth are poorly studied. S100A7, a pro-inflammatory molecule has been shown to enhance breast cancer growth and metastasis. However, the S100A7-mediated molecu
Externí odkaz:
https://doaj.org/article/828bc8c8787a4e5b8a20e7cf1c6fef35
Autor:
Song Sun, Xiaoyi Zou, Duo Wang, Yige Liu, Zhenming Zhang, Junchen Guo, Rongzhe Lu, Wei Huang, Shanjie Wang, Zhaoying Li, Jiangtian Tian, Huai Yu, Jin Fu, Shaohong Fang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 158, Iss , Pp 114152- (2023)
Background: Neutrophil extracellular traps (NETs) closely link inflammation and thrombosis. The immune-related GTPase family M protein (IRGM) and its ortholog of mouse IRGM1 are positively correlated with plaque rupture during atherosclerosis process
Externí odkaz:
https://doaj.org/article/b0186ab68b2d4bce81279762408f8605
Autor:
Mario Cioce, Claudia Canino, Harvey Pass, Giovanni Blandino, Sabrina Strano, Vito Michele Fazio
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background High resistance to therapy and poor prognosis characterizes malignant pleural mesothelioma (MPM). In fact, the current lines of treatment, based on platinum and pemetrexed, have limited impact on the survival of MPM patients. Adap
Externí odkaz:
https://doaj.org/article/c87f2a9f8aa34141ad564cf7c176bf72