Zobrazeno 1 - 10
of 3 168
pro vyhledávání: '"cGAS‐STING"'
Autor:
Chen-Yu Zhang, An-Jun Ou, Ling Jin, Nan-Shi-Yu Yang, Ping Deng, Cha-Xiang Guan, Xiao-Ting Huang, Jia-Xi Duan, Yong Zhou
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Cadmium is a ubiquitous toxic metal and environmental pollutant. More and more studies have shown that cadmium exposure can damage lung function. Alveolar epithelial cells (AECs) are structural cells that maintain the stability of
Externí odkaz:
https://doaj.org/article/c1ce4849be904bd0bb2a0f7178439526
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. The ketogenic diet (KD), a diet high in fat and low in carbohydrates, has been applied clinically for the treatment of obese women with PCOS. We
Externí odkaz:
https://doaj.org/article/dbbbedcbd5594e7990d4fcfedc3a62c5
Autor:
Jian Peng, Dong-Ling Quan, Guang Yang, Lin-Tao Wei, Zhuan Yang, Zhi-Ying Dong, Yi-Ming Zou, Ying-Ke Hou, Jin-Xiang Chen, Lin Lv, Bin Sun
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Radiotherapy (RT) stands as a frontline treatment modality in clinical breast oncology, yet challenges like ROS reduction, high toxicity, non-selectivity, and hypoxia hinder efficacy. Additionally, RT administered at different doses can indu
Externí odkaz:
https://doaj.org/article/5eccb7157ceb4e24895e8ee8b3e1224f
Autor:
Thurid Lauf, Antje Häder, Franziska Hornung, Yasmina Reisser, Sandor Nietzsche, Fabian Schanz, Verena Trümper, Aldona Jeznach, Sascha Brunke, Torsten Doenst, Tomasz Skirecki, Bettina Löffler, Stefanie Deinhardt-Emmer
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Ageing is a major risk factor that contributes to increased mortality and morbidity rates during influenza A virus (IAV) infections. Macrophages are crucial players in the defense against viral infections and display impaired function during
Externí odkaz:
https://doaj.org/article/a53e4bc03a7c4494b52dfbb0481c6c0d
Autor:
Kyoung-Seok Oh, Ah-Rong Nam, Ju-Hee Bang, Yoojin Jeong, Sea Young Choo, Hyo Jung Kim, Su In Lee, Jae-Min Kim, Jeesun Yoon, Tae-Yong Kim, Do-Youn Oh
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Although the efficacy of trastuzumab deruxtecan (T-DXd) against HER2-positive gastric cancers (GCs) has driven its clinical application, the precise mechanisms governing its immunomodulatory role remain unclear. In this study, we examined th
Externí odkaz:
https://doaj.org/article/fda6107846d1415994d39964ffe7e727
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 10685-10697 (2024)
Ana RS Ribeiro,1,2 Theresa Neuper,1– 3 Jutta Horejs-Hoeck1– 3 1Department of Biosciences and Medical Biology, Paris Lodron University of Salzburg, Salzburg, Austria; 2Cancer Cluster Salzburg (CCS), Salzburg, 5020, Austria; 3Center for Tumor biolo
Externí odkaz:
https://doaj.org/article/8d5fb812996c48ae95a5e5f47c27d6ed
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The cGAS-STING signaling pathway is a critical component of the innate immune response, playing a significant role in various diseases. As a central element of this pathway, STING responds to both endogenous and exogenous DNA stimuli, triggering the
Externí odkaz:
https://doaj.org/article/c7cae8e8df0e4bb6876110b5dfb71e4e
Autor:
Jun Hu, Mengxiang Tian
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
The innate immune response is the body's first line of defense against external pathogens and endogenous damage signals. The cGAS-STING pathway is a crucial component of the innate immune response, playing a key role in initiating antiviral and anti-
Externí odkaz:
https://doaj.org/article/dfce2b15645d422e83e95f6f92fe2b20
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract The innate immune system is the first responder to infectious agents, cellular debris, and cancerous growths. This system plays critical roles in the antitumor immune responses by boosting and priming T cell-mediated cytotoxicity but is unde
Externí odkaz:
https://doaj.org/article/a0372b953f7d4b58bb992040a81e4e79
Autor:
Xiaodian Zhang, Hailong Tian, Yang Chen, Baichuan Liang, Edouard C. Nice, Canhua Huang, Na Xie, Shaojiang Zheng
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Immunotherapy has shown marked progress in promoting systemic anti-colorectal cancer (CRC) clinical effects. For further effectively sensitizing CRC to immunotherapy, we have engineered a pH-sensitive zeolitic imidazolate framework-8 (CS/NPs
Externí odkaz:
https://doaj.org/article/c680ef09da4d46f4a74a0ba001838a51