Zobrazeno 1 - 10
of 1 076
pro vyhledávání: '"cAMP/PKA"'
Autor:
Weijun Liu, Qingbo Li, Weizhi Fang, Lei Cai, Zhengkun Wang, Bowen Kou, Chuankun Zhou, Yichi Zhou, Zhi Yao, Mengcheng Wei, Shishuang Zhang
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-13 (2024)
Abstract Background Reduction of inflammatory damage and inhibition of nucleus pulposus (NP) apoptosis are considered to be the main effective therapy idea to reverse the intervertebral disc degeneration (IDD) and alleviate the chronic low back pain.
Externí odkaz:
https://doaj.org/article/7f63f5129fa440318f801144c331588a
Autor:
Yao Zhang, Zelong She, Ruolan He, Shuangyan Yao, Xiang Li, Xiaoguang Liu, Xinming Yin, Jizhen Wei, Mengfang Du, Shiheng An
Publikováno v:
Journal of Integrative Agriculture, Vol 23, Iss 8, Pp 2735-2751 (2024)
Conogethes punctiferalis is a crop and fruit pest that has caused serious economic losses to agricultural production. This pest relies heavily on its sex pheromone to ensure sexual encounters and subsequent mating success. However, the molecular mech
Externí odkaz:
https://doaj.org/article/f64ae3cd92d94e34a75e52a58e0157fb
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundDysregulated and excessive inflammatory reactions can lead to tissue damage, which is the underlying cause of most human diseases. Menisoxoisoaporphine A (MA), a novel oxoisoaporphine alkaloid, was obtained from Menispermi Rhizoma, a tradit
Externí odkaz:
https://doaj.org/article/b1e03e216b1a4255b0b46491c4ff2fad
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e35558- (2024)
Diabetic gastroparesis, a common complication of type 2 diabetes (T2DM), presents a significant treatment challenge. FoxiangSan is emerging as a potential therapy. FoxiangSan is a traditional Chinese medicine formula with the potential for treating d
Externí odkaz:
https://doaj.org/article/132e3a31ddb942008f7914314c5d0f56
Autor:
Chu Jiang, Jun Guan, Xiangrong Tang, Yichun Zhang, Xiangyu Li, Yuting Li, Zhiheng Chen, Jing Zhang, Jia-Da Li
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 18 (2024)
Bisphenol A (BPA) is a widely used plasticizer known to cause various disorders. Despite a global reduction in the use of BPA-containing products, prenatal exposure to low-dose BPA, even those below established safety limits, has been linked to neuro
Externí odkaz:
https://doaj.org/article/80456cf8d2b0408d88635b872909d942
Autor:
Yuchen Qin, Weiyu Huang, Zijiang Wang, Chunting Wang, Chen Wang, Meng Zhang, Shengting Wu, Gaoyang Wang, Fenghong Zhao
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 279, Iss , Pp 116464- (2024)
1,2-Dichloroethane (1,2-DCE) is a powerfully toxic neurotoxin, which is a common environmental pollutant. Studies have indicated that 1,2-DCE long-term exposure can result in adverse effects. Nevertheless, the precise mechanism remains unknown. In th
Externí odkaz:
https://doaj.org/article/35079e99d9a74b6b8aa3dca860021655
Autor:
Fiorella Galello, Mariana Bermúdez-Moretti, María Clara Ortolá Martínez, Silvia Rossi, Paula Portela
Publikováno v:
Microbial Cell, Vol 11, Pp 90-105 (2024)
The yeast Saccharomyces cerevisiae is widely used in food and non-food industries. During industrial fermentation yeast strains are exposed to fluctuations in oxygen concentration, osmot-ic pressure, pH, ethanol concentration, nutrient availability a
Externí odkaz:
https://doaj.org/article/a5de2894420a4b20a8510e742a616db3
Autor:
Xiufei Cao, Huixing Guo, Yongjun Dai, Guangzhen Jiang, Wenbin Liu, Xiangfei Li, Dingdong Zhang, Yangyang Huang, Xi Wang, Haokun Hua, Jianfeng Wang, Keke Chen, Cheng Chi, Hengtong Liu
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103096- (2024)
Oxidative stress in muscles is closely related to the occurrence of insulin resistance, muscle weakness and atrophy, age-related sarcopenia, and cancer. Aldehydes, a primary oxidation intermediate of polyunsaturated fatty acids, have been proven to b
Externí odkaz:
https://doaj.org/article/aa32bf80fb0a4273b85ba5287ee8ff92
Publikováno v:
Virus Research, Vol 341, Iss , Pp 199313- (2024)
Human immunodeficiency virus-1 (HIV-1) infection can cause chronic activation, exhaustion, and anergy of the immune system. Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is an immune checkpoint molecule, which plays an important role in immune
Externí odkaz:
https://doaj.org/article/ef8b8c05ebb84418812a7f57a9f69e05
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27161- (2024)
The aim of this study was to investigate the possible molecular mechanism of Scutellaria baicalensis Georgi stems and leaves flavonoids (SSF) in Alzheimer's disease (AD). The active ingredients of SSF and their targets were identified via network pha
Externí odkaz:
https://doaj.org/article/34e25cb77a0847b8a77021c36084ed5c