Zobrazeno 1 - 10
of 534
pro vyhledávání: '"c3a receptor"'
Autor:
Chongjian Wang, Zhiyu Wang, Jing Xu, Hongkun Ma, Kexin Jin, Tingting Xu, Xiaoxia Pan, Xiaobei Feng, Wen Zhang
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 10, p 238 (2023)
Background: Renin-dependent hypertension with tubulointerstitial injury remains a problem with high prevalence in the clinic. However, whether and how renin participates in tubulointerstitial injury remains incompletely understood. New evidence sugge
Externí odkaz:
https://doaj.org/article/a810ef93a2e44f09bdaf6d34a7c41e2c
Autor:
Fumihiko Nagano, Tomohiro Mizuno, Masaki Imai, Kazuo Takahashi, Naotake Tsuboi, Shoichi Maruyama, Masashi Mizuno
Publikováno v:
FEBS Open Bio, Vol 12, Iss 1, Pp 192-202 (2022)
Acute lung injury (ALI) occurs in patients with severe sepsis and has a mortality rate of 40%–60%. Severe sepsis promotes the release of histones from dying cells, which can induce platelet aggregation, activate coagulation and cause endothelial ce
Externí odkaz:
https://doaj.org/article/65e0ac3b30114d7d945fdd68e6189f65
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Retinal degeneration causes vision loss and threatens the health of elderly individuals worldwide. Evidence indicates that the activation of the complement system is associated with retinal degeneration. However, the mechanism of complement signaling
Externí odkaz:
https://doaj.org/article/046c6721f954451389d27dc7b2abd19a
Autor:
Susanne Mommert, Lisa Doenni, Phillip Szudybill, Christoph Zoeller, Frerk Hinnerk Beyer, Thomas Werfel
Publikováno v:
Journal of Innate Immunity, Pp 1-15 (2021)
To study the molecular interplay between TLRs and complement representing ancient danger-sensing mechanisms, we examined the regulation of the C3a/anaphylatoxin C3a receptor (C3aR) axis in normal human epidermal keratinocytes (NHEKs) by treatment wit
Externí odkaz:
https://doaj.org/article/0f45f8d4e64a4ed4a86d3475116f4b4f
Autor:
Chi Shu, Haoran Zha, Haixia Long, Xinxin Wang, Fei Yang, Jianbao Gao, Chunyan Hu, Li Zhou, Bo Guo, Bo Zhu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-14 (2020)
Abstract Background Mounting evidence suggests that complement components promote tumor progression via modulating immune suppression, angiogenesis, or tumor cell proliferation. However, the role of C3a-C3aR signaling in regulating lung metastasis of
Externí odkaz:
https://doaj.org/article/93c5bf410543482f849997243f5346c2
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Complement component 3 fragment C3a is an anaphylatoxin involved in promoting cellular responses important in immune response and host defense. Its receptor (C3a receptor, C3aR) is distributed on the plasma membrane; however, lysosomal localization i
Externí odkaz:
https://doaj.org/article/5eec7a1412b840998e6a7bf81a860b05
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The pathogenesis of some kidney diseases is closely associated with complement activation, where the C3a/C3a receptor (C3aR) might play a crucial role. C3a/C3aR has dual roles and may exert anti-inflammatory or pro-inflammatory effects depending on d
Externí odkaz:
https://doaj.org/article/9f4d615953db47a8a82d9e2b46eb6f8a
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Masashi Mizuno, Fumihiko Nagano, Tomohiro Mizuno, Kazuo Takahashi, Shoichi Maruyama, Masaki Imai, Naotake Tsuboi
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 12, Iss 1, Pp 192-202 (2022)
FEBS Open Bio, Vol 12, Iss 1, Pp 192-202 (2022)
Acute lung injury (ALI) occurs in patients with severe sepsis and has a mortality rate of 40%–60%. Severe sepsis promotes the release of histones from dying cells, which can induce platelet aggregation, activate coagulation and cause endothelial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87aec528eb5506802ce154f0ddf289b5
https://doi.org/10.1002/2211-5463.13322
https://doi.org/10.1002/2211-5463.13322