Zobrazeno 1 - 10
of 10
pro vyhledávání: '"c21orf59"'
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Cilia are highly conserved organelles present in almost all types of eukaryotic cells, and defects in cilia structure and/or function are related to many human genetic disorders. Single-celled ciliated protists, which possess diverse types of cilia,
Externí odkaz:
https://doaj.org/article/16ad39f6761344b9a0069646d2f7c9e2
Autor:
Kimberly M. Jaffe, Daniel T. Grimes, Jodi Schottenfeld-Roames, Michael E. Werner, Tse-Shuen J. Ku, Sun K. Kim, Jose L. Pelliccia, Nicholas F.C. Morante, Brian J. Mitchell, Rebecca D. Burdine
Publikováno v:
Cell Reports, Vol 14, Iss 8, Pp 1841-1849 (2016)
Cilia are microtubule-based projections that function in the movement of extracellular fluid. This requires cilia to be: (1) motile and driven by dynein complexes and (2) correctly polarized on the surface of cells, which requires planar cell polarit
Externí odkaz:
https://doaj.org/article/6492440964db4e188eb355556e19b34b
Autor:
Yarden Sarouf, Amir Vardi, Ben Pode-Shakked, Yishay Ben Moshe, Alvit Veber, Gideon Rechavi, Yair Anikster, Dina Marek-Yagel, Odelia Chorin, Annick Raas-Rothschild, Shrikant Mane, Yoav Bolkier, Yishay Salem, Danit Atias-Varon, Omer Shlomovitz, Elisheva Javasky, Tal Tirosh-Wagner, Uriel Katz, Jeffrey M. Jacobson, Orna Staretz-Chacham, Nechama Shalva, Ortal Barel, David Mishali, Maayan Kagan, Asaf Vivante, Aviva Eliyahu
Publikováno v:
Journal of Medical Genetics. 59:691-696
BackgroundThe molecular basis of heterotaxy and congenital heart malformations associated with disruption of left–right asymmetry is broad and heterogenous, with over 25 genes implicated in its pathogenesis thus far.ObjectiveWe sought to elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2860acb43e08c30e8928380ab6ba385f
https://doi.org/10.1136/jmedgenet-2021-107775
https://doi.org/10.1136/jmedgenet-2021-107775
Autor:
Luis Sanchez-Pulido, Chris P. Ponting
Publikováno v:
Journal of Molecular Biology
Graphical abstract
Highlights • Co-evolution-based methods extend the homology detection horizon of protein sequence analysis. • Predicted contact maps help predict domain boundaries and tertiary structures. • Such maps also aid in identif
Highlights • Co-evolution-based methods extend the homology detection horizon of protein sequence analysis. • Predicted contact maps help predict domain boundaries and tertiary structures. • Such maps also aid in identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b7b22b0a7a1c8f7a6773bc0dd7d6b6
https://pubmed.ncbi.nlm.nih.gov/34139218
https://pubmed.ncbi.nlm.nih.gov/34139218
Akademický článek
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Autor:
Austin, Christina Anne
Cilia and flagella are hair-like projections found on the surface of virtually every vertebrate cell. These microtubule-based organelles are historically known for their striking motility, a valuable tool for the manipulation of fluid environments. I
Externí odkaz:
http://dissertations.umi.com/gsas.harvard:10974
http://nrs.harvard.edu/urn-3:HUL.InstRepos:11051192
http://nrs.harvard.edu/urn-3:HUL.InstRepos:11051192
Autor:
Yan Liu, Kenneth N. Olivier, Scott D. Sagel, Peadar G. Noone, Rannar Airik, Jonathan D. Porath, Johnny L. Carson, Maimoona B Zariwala, Christina Austin-Tse, Stephanie D. Davis, Iain A. Drummond, Eileen T. O'Toole, Markus Schueler, Renée M. Gilberti, Narendra Pathak, Ramila S. Patel-King, Raqual Bower, Jessica E. Pittman, Margaret W. Leigh, Nathan E. Hellman, Mary E. Porter, Michael R. Knowles, Douglas Tritschler, Heon Yung Gee, Jeffry J. Atkinson, Daw Yang Hwang, Stephen M. King, Carlos Milla, Daniela A. Braun, Thomas W. Ferkol, Heymut Omran, Moumita Chaki, Toby W. Hurd, Jan Halbritter, Friedhelm Hildebrandt, Stefan Kohl, Svjetlana Lovric, Niki T. Loges, Margaret Rosenfeld, Jennifer R. Panizzi, Sharon D. Dell, Katrina A. Diaz, Edgar A. Otto
Publikováno v:
American journal of human genetics. 93(4)
Primary ciliary dyskinesia (PCD) is caused when defects of motile cilia lead to chronic airway infections, male infertility, and situs abnormalities. Multiple causative PCD mutations account for only 65% of cases, suggesting that many genes essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6984ac78aa27e090ad1b40247886e09f
https://pubmed.ncbi.nlm.nih.gov/24745522
https://pubmed.ncbi.nlm.nih.gov/24745522
Akademický článek
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Akademický článek
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Autor:
Jose L Pelliccia, Daniel T. Grimes, Brian J. Mitchell, Jodi Schottenfeld-Roames, Nicholas F.C. Morante, Michael E. Werner, Tse Shuen J Ku, Sun K. Kim, Kimberly M. Jaffe, Rebecca D. Burdine
Publikováno v:
Cell Reports, Vol 14, Iss 8, Pp 1841-1849 (2016)
SummaryCilia are microtubule-based projections that function in the movement of extracellular fluid. This requires cilia to be: (1) motile and driven by dynein complexes and (2) correctly polarized on the surface of cells, which requires planar cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4366c860932265d81226f26776438ebe