A broadly neutralizing monoclonal antibody induces broad protection against heterogeneous PRRSV strains in piglets

Autor: Zhigang Zhang, Tianshu Zhai, Mingshuo Li, Kun Zhang, Jingrui Li, Xu Zheng, Chaonan Tian, Rui Chen, Jianhui Dong, En-Min Zhou, Yuchen Nan, Chunyan Wu

Publikováno v: Veterinary Research, Vol 52, Iss 1, Pp 1-23 (2021)

Abstract Neutralizing antibodies (NAbs) have attracted attention as tools for achieving PRRSV control and prevention, but viral antigenic variation undermines the abilities of NAbs elicited by attenuated PRRSV vaccines to confer full protection again

Externí odkaz: https://doaj.org/article/422fc3de498b47ae925fdd9f6ab535ba

A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques

Autor: Volkmann, Ariane, Koopman, Gerrit, Mooij, Petra, Verschoor, Ernst J., Verstrepen, Babs E., Bogers, Willy M.J.M., Idorn, Manja, Paludan, Søren R., Vang, Søren, Nielsen, Morten A., Sander, Adam F., Schmittwolf, Carolin, Hochrein, Hubertus, Chaplin, Paul

Publikováno v: Front. Immunol
Volkmann, A, Koopman, G, Mooij, P, Verschoor, E J, Verstrepen, B E, Bogers, W M J M, Idorn, M, Paludan, S R, Vang, S, Nielsen, M A, Sander, A F, Schmittwolf, C, Hochrein, H & Chaplin, P 2022, ' A capsid virus-like particle-based SARS-CoV-2 vaccine induces high levels of antibodies and protects Rhesus macaques ', Frontiers in Immunology, vol. 13, pp. 857440 . https://doi.org/10.3389/fimmu.2022.857440
Volkmann, A, Koopman, G, Mooij, P, Verschoor, E J, Verstrepen, B E, Bogers, W M J M, Idorn, M, Paludan, S R, Vang, S, Nielsen, M A, Sander, A F, Schmittwolf, C, Hochrein, H & Chaplin, P 2022, ' A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques ', Frontiers in Immunology, vol. 13, 857440 . https://doi.org/10.3389/fimmu.2022.857440

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide pandemic. Here, we present non-human primate immunogenicity and protective efficacy data generated with the capsid virus-like particle (cVLP)-based vaccine ABNCoV2 th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9416c490fd115b213c70e63f85aa3c9f
https://pubmed.ncbi.nlm.nih.gov/35479095

A broadly neutralizing monoclonal antibody induces broad protection against heterogeneous PRRSV strains in piglets

Autor: Chunyan Wu, Jingrui Li, Xu Zheng, Mingshuo Li, En-Min Zhou, Jianhui Dong, Chaonan Tian, Kun Zhang, Zhang Zhigang, Rui Chen, Yuchen Nan, Tianshu Zhai

Publikováno v: Veterinary Research
Veterinary Research, Vol 52, Iss 1, Pp 1-23 (2021)
Veterinary Research, BioMed Central, 2021, 52 (1), pp.45. ⟨10.1186/s13567-021-00914-0⟩

Neutralizing antibodies (NAbs) have attracted attention as tools for achieving PRRSV control and prevention, but viral antigenic variation undermines the abilities of NAbs elicited by attenuated PRRSV vaccines to confer full protection against hetero

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc52320a99a7cbb6a5759c866b3be96c
http://europepmc.org/articles/PMC7962380

Engineering antibody-like inhibitors to prevent and treat HIV-1 infection

Autor: Michael Farzan, Matthew R. Gardner

Publikováno v: Current Opinion in HIV and AIDS

Purpose of review Here we discuss recently developed HIV-1 entry inhibitors that can target multiple epitopes on the HIV-1 envelope glycoprotein (Env), with an emphasis on eCD4-Ig. Some of these inhibitors are more potent and broader than any single

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48fbc4da3d5ba764001014bcee0d268
https://doi.org/10.1097/coh.0000000000000367

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