Zobrazeno 1 - 10
of 2 067
pro vyhledávání: '"bridging integrator 1"'
Autor:
Jing Li, Pia Balmaceda, Thuy Ha, Joseph R. Visker, Nicole Maalouf, Eugene Kwan, Guillaume L. Hoareau, Michel Accad, Ravi Ranjan, Craig H. Selzman, Stavros G. Drakos, Robin M. Shaw, TingTing Hong
Publikováno v:
npj Regenerative Medicine, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Heart failure (HF) is a major cause of mortality and morbidity worldwide, yet with limited therapeutic options. Cardiac bridging integrator 1 (cBIN1), a cardiomyocyte transverse-tubule (t-tubule) scaffolding protein which organizes the calci
Externí odkaz:
https://doaj.org/article/8a87c03e802d46abbc4baf6b3c5319f7
Akademický článek
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Autor:
Zhang, Xingyu1 (AUTHOR), Zou, Li1,2 (AUTHOR), Tang, Li1 (AUTHOR), Xiong, Min1 (AUTHOR), Yan, Xiao-Xin3 (AUTHOR), Meng, Lanxia1 (AUTHOR), Chen, Guiqin1 (AUTHOR), Xiong, Jing1 (AUTHOR), Nie, Shuke1 (AUTHOR), Zhang, Zhaohui1 (AUTHOR), Chen, Qiang4 (AUTHOR), Zhang, Zhentao1,5 (AUTHOR) zhentaozhang@whu.edu.cn
Publikováno v:
PLoS Biology. 1/11/2024, Vol. 22 Issue 1, p1-27. 27p.
Autor:
Xingyu Zhang, Li Zou, Li Tang, Min Xiong, Xiao-Xin Yan, Lanxia Meng, Guiqin Chen, Jing Xiong, Shuke Nie, Zhaohui Zhang, Qiang Chen, Zhentao Zhang
Publikováno v:
PLoS Biology, Vol 22, Iss 1, p e3002470 (2024)
The bridging integrator 1 (BIN1) gene is an important risk locus for late-onset Alzheimer's disease (AD). BIN1 protein has been reported to mediate tau pathology, but the underlying molecular mechanisms remain elusive. Here, we show that neuronal BIN
Externí odkaz:
https://doaj.org/article/324bc7f1edec43e6a5dc0fae209c4bec
Autor:
Saberi, Alia1, Niroomand, Zohair2,3 z.niroomand@rmf.landeskrankenhaus.de, Ghayeghran, Amirreza1 gham1346@gmail.com, Ajamian, Farzam4, Karimi, Ashkan2,5, Shirkouhi, Samaneh Ghorbani2,6, Mirzanejad, Laleh4, Gooraji, Somayeh Ahmadi7, Andalib, Sasan2,8,9
Publikováno v:
Caspian Journal of Neurological Sciences. Spring2023, Vol. 9 Issue 2, p71-77. 7p.
Autor:
Alia Saberi, Zohair Niroomand, Amirreza Ghayeghran, Farzam Ajamian, Ashkan Karimi, Samaneh Ghorbani Shirkouhi, Laleh Mirzanejad, Somayeh Ahmadi Gooraji, Sasan Andalib
Publikováno v:
Caspian Journal of Neurological Sciences, Vol 9, Iss 2, Pp 71-77 (2023)
Background: Alzheimer’s Disease (AD) is the most common type of dementia. The role of genetic factors in AD development remains non-demonstrated. Objectives: In this study, we aimed to investigate the association between one of the BIN1 gene’s si
Externí odkaz:
https://doaj.org/article/bb4d43a0170f420e949c59b6ed73f5ad
Akademický článek
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Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Background: Cardiac bridging integrator 1 (cBIN1) organizes transverse tubule (t-tubule) membrane calcium handling microdomains required for normal beat-to-beat contractility. cBIN1 is transcriptionally reduced in heart failure (HF). We recently foun
Externí odkaz:
https://doaj.org/article/1834fe31375d4a1389d9768e2580dbfa
Publikováno v:
Progress in Modern Biomedicine. Aug2019, Vol. 19 Issue 15, p2915-2919. 5p.