Zobrazeno 1 - 10
of 3 435
pro vyhledávání: '"brain slices"'
Autor:
Jessica Giacomoni, Malin Åkerblom, Mette Habekost, Alessandro Fiorenzano, Janko Kajtez, Marcus Davidsson, Malin Parmar, Tomas Björklund
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Direct neural conversion of endogenous non-neuronal cells, such as resident glia, into therapeutic neurons has emerged as a promising strategy for brain repair, aiming to restore lost or damaged neurons. Proof-of-concept has been obtained from animal
Externí odkaz:
https://doaj.org/article/c3d7e2d6b3b847adb1d3068e5cf75a20
Autor:
Katharina Steiner, Christian Humpel
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 6, p 232 (2024)
Background: Alzheimer’s disease is characterized by extracellular beta-amyloid plaques, intraneuronal tau neurofibrillary tangles and excessive neurodegeneration. The mechanisms of neuron degeneration and the potential of these neurons to form new
Externí odkaz:
https://doaj.org/article/dd8e08737a5c46e1a02884f872d5a6f2
Akademický článek
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Autor:
Petrilla Jayaprakash, Dmytro Isaev, Keun-Hang Susan Yang, Rami Beiram, Murat Oz, Bassem Sadek
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 482 (2024)
Studying the involvement of nicotinic acetylcholine receptors (nAChRs), specifically α7-nAChRs, in neuropsychiatric brain disorders such as autism spectrum disorder (ASD) has gained a growing interest. The flavonoid apigenin (APG) has been confirmed
Externí odkaz:
https://doaj.org/article/bba029305b4c4ac9b0e217ca16ac2717
Akademický článek
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Autor:
Francesca Pischiutta, Helena Cavaleiro, Enrico Caruso, Francesca Tribuzio, Noemi Di Marzo, Federico Moro, Firas Kobeissy, Kevin K. Wang, António J. Salgado, Elisa R. Zanier
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Traumatic brain injury (TBI) is a major worldwide neurological disorder with no neuroprotective treatment available. Three-dimensional (3D) in vitro models of brain contusion serving as a screening platform for drug testing are lacking. Here we devel
Externí odkaz:
https://doaj.org/article/00bf870a8179441d88f7b5cd517e8283
Autor:
Michael McKenna, Jeremy R. Filteau, Brendan Butler, Kenneth Sluis, Michael Chungyoun, Nels Schimek, Elizabeth Nance
Publikováno v:
Journal of Biological Engineering, Vol 16, Iss 1, Pp 1-22 (2022)
Abstract Background The brain extracellular environment is involved in many critical processes associated with neurodevelopment, neural function, and repair following injury. Organization of the extracellular matrix and properties of the extracellula
Externí odkaz:
https://doaj.org/article/2e9e5164c35b4efebe66d0986b646b78
Autor:
Dhwani S. Korde, Christian Humpel
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 165 (2024)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that is characterized by amyloid-beta (Aβ) plaques and tau neurofibrillary tangles (NFT). Modelling aspects of AD is challenging due to its complex multifactorial etiology and pa
Externí odkaz:
https://doaj.org/article/5bb52e1e30a748fdaa9f5c8ca1746252
Autor:
Katharina Steiner, Christian Humpel
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 3 (2023)
In Alzheimer’s disease, the blood–brain barrier breakdown, blood vessel damage and re-organization are early events. Deposits of the small toxic peptide beta-amyloid (Aβ) cause the formation of extracellular plaques and accumulate in vessels dis
Externí odkaz:
https://doaj.org/article/4f82a943b6ef42909067c7b997cdf526
Akademický článek
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