Zobrazeno 1 - 10
of 498
pro vyhledávání: '"brain organoid"'
Autor:
Yinbing Zhang, Cheng Tang, Yao He, Yingqian Zhang, Qinxi Li, Ting Zhang, Bangcheng Zhao, Aiping Tong, Qixing Zhong, Zhihui Zhong
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117540- (2024)
Aims: To investigate the therapeutic effects and mechanisms of Semaglutide in Alzheimer's disease (AD), and identify its potential targets. Methods: We systematically evaluated the effect of Semaglutide on Alzheimer's disease (AD), using both mice an
Externí odkaz:
https://doaj.org/article/66b32bb1e3df4e19b8b35302d8eadcec
Publikováno v:
Advanced NanoBiomed Research, Vol 4, Iss 9, Pp n/a-n/a (2024)
Though animal models are still the gold standard for fundamental biological studies and drug evaluation for brain diseases, concerns arise from an apparent lack of reflecting the human genetics and pathophysiology. Recently, human avatars such as bra
Externí odkaz:
https://doaj.org/article/0afeaf50e3954a91a7e9825d40b5e1e1
Autor:
Shujin CHEN, Chonghuai YAN
Publikováno v:
环境与职业医学, Vol 41, Iss 3, Pp 342-347 (2024)
Since the 19th century, the emergence of model systems has helped researchers further understand cellular signaling pathways, identify potential drug targets, and conduct environmental toxicological studies. Exogenous chemicals, such as pollutants, d
Externí odkaz:
https://doaj.org/article/7152450032224fe88288f00d2fbecc8f
Autor:
Hye Sung Kim, Yang Xiao, Xuejing Chen, Siyu He, Jongwon Im, Moshe J. Willner, Michael O. Finlayson, Cong Xu, Huixiang Zhu, Se Joon Choi, Eugene V. Mosharov, Hae‐Won Kim, Bin Xu, Kam W. Leong
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Understanding the impact of long‐term opioid exposure on the embryonic brain is critical due to the surging number of pregnant mothers with opioid dependency. However, this has been limited by human brain inaccessibility and cross‐specie
Externí odkaz:
https://doaj.org/article/b46900ca4b6748a09f94984845285e8f
Autor:
Evans, John H., author
Publikováno v:
Disembodied Brains : Understanding our Intuitions on Human-Animal Neuro-Chimeras and Human Brain Organoids, 2024.
Externí odkaz:
https://doi.org/10.1093/oso/9780197750704.003.0006
Autor:
Evans, John H., author
Publikováno v:
Disembodied Brains : Understanding our Intuitions on Human-Animal Neuro-Chimeras and Human Brain Organoids, 2024.
Externí odkaz:
https://doi.org/10.1093/oso/9780197750704.003.0004
Autor:
Evans, John H., author
Publikováno v:
Disembodied Brains : Understanding our Intuitions on Human-Animal Neuro-Chimeras and Human Brain Organoids, 2024.
Externí odkaz:
https://doi.org/10.1093/oso/9780197750704.003.0003
Autor:
Evans, John H., author
Publikováno v:
Disembodied Brains : Understanding our Intuitions on Human-Animal Neuro-Chimeras and Human Brain Organoids, 2024.
Externí odkaz:
https://doi.org/10.1093/oso/9780197750704.003.0005
Autor:
Wei Niu, Lu Deng, Sandra P. Mojica-Perez, Andrew M. Tidball, Roksolana Sudyk, Kyle Stokes, Jack M. Parent
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
IntroductionProtocadherin-19 (PCDH19)-Clustering Epilepsy (PCE) is a developmental and epileptic encephalopathy caused by loss-of-function variants of the PCDH19 gene on the X-chromosome. PCE affects females and mosaic males while male carriers are l
Externí odkaz:
https://doaj.org/article/395f09dd4fa84851b5504c0fb0d96b38
Publikováno v:
Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101593- (2024)
Here, the protective mechanism of Codonopsis pilosula polysaccharide (CpP) against mouse brain organoids (mBO) damage was analyzed, and the rotenone affected the genomic epigenetic modifications and physiological activity of mouse brain organoids was
Externí odkaz:
https://doaj.org/article/ac66b2cb34af4931b929249743a1b61d