Zobrazeno 1 - 10
of 2 373
pro vyhledávání: '"brain delivery"'
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 8463-8483 (2024)
Zemin Ou, Yun You, Hong Yi, Xiaoqian Liu, Yan Tong, Dewen Liu, Jinyu Wang Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of ChinaCorrespondence: Dewen Liu; Jinyu Wang, Institute of Chinese
Externí odkaz:
https://doaj.org/article/abe148b540c1480d8943887664bf9c3f
Autor:
Rebecca Faresjö, Elisabet O. Sjöström, Tiffany Dallas, Magnus M. Berglund, Jonas Eriksson, Dag Sehlin, Stina Syvänen
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Neurodegenerative diseases such as Alzheimer’s disease (AD) pose substantial challenges to patients and health-care systems, particularly in countries with aging populations. Immunotherapies, including the marketed antibodies lecanemab (Leqembi®)
Externí odkaz:
https://doaj.org/article/041fd12ae7354b68b4c4b27fadafe24b
Autor:
Shuo Zhang, Yishu Wang, Mingting Zhu, Bingyang Liu, Wenpu Zhao, Shuai Zhang, Ji Xia, Lei Shi, Peng Tang, Feiqian Wang, Siyuan Zhang, Mingxi Wan, Daocheng Wu, Wei Gao
Publikováno v:
Aggregate, Vol 5, Iss 5, Pp n/a-n/a (2024)
Abstract To enhance the anesthetic efficacy and reduce toxic side effects, a strategy is proposed involving the utilization of general anesthetics of Propofol (Pro) and Etomidate (Eto) to synergistic inhibition GABA receptors simultaneously. Four‐i
Externí odkaz:
https://doaj.org/article/2b5376089e514e1a9d68d57ccb40a37a
Publikováno v:
Materials Today Bio, Vol 28, Iss , Pp 101244- (2024)
Glioma is a common primary malignant brain tumor with low survival rate. Immunotherapy with immune checkpoints inhibitors (ICI) can be a choice for glioma management, and extracellular vesicles (EVs) are recognized as a potential drug delivery system
Externí odkaz:
https://doaj.org/article/0e25654553e04a1bb12612a3c5cd80c6
Autor:
Marco Cavaco, Patrícia Fraga, Javier Valle, Ruben D. M. Silva, Lurdes Gano, João D. G. Correia, David Andreu, Miguel A. R. B. Castanho, Vera Neves
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Blood–brain barrier (BBB) peptide-shuttles (BBBpS) are able to translocate the BBB and reach the brain. Despite the importance of brain targeting in pharmacology, BBBpS are poorly characterized. Currently, their development relies on the e
Externí odkaz:
https://doaj.org/article/ff105247e7514a8eb2dac249aa0d9bfc
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 4857-4875 (2024)
Aleksandr Kakinen,1,2 Yuhao Jiang,2 Thomas Paul Davis,2 Tambet Teesalu,3,4 Mart Saarma1 1Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland; 2Australian Institute for Bioengineering and Nanotechnology, University of Queensl
Externí odkaz:
https://doaj.org/article/f9e5395d26be48b996bd77b06e1eb371
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-26 (2024)
Abstract Neurodegenerative diseases are characterized by extensive loss of function or death of brain cells, hampering the life quality of patients. Brain-targeted drug delivery is challenging, with a low success rate this far. Therefore, the applica
Externí odkaz:
https://doaj.org/article/b9a96212d3db4fe493515c82e381c731
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 1767-1807 (2024)
Jain Koo,1,2 Chaemin Lim,3 Kyung Taek Oh1,2 1Department of Global Innovative Drugs, The Graduate School of Chung-Ang University, Seoul, Republic of Korea; 2College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea; 3College of Pharmacy, CHA
Externí odkaz:
https://doaj.org/article/02fefd9addfe4eb9b71753db10fdd3fd
Publikováno v:
Nanotechnology, Science and Applications, Vol Volume 17, Pp 1-19 (2024)
Mohammed Layth Hamzah,1,2 Hanan Jalal Kassab1 1Department of Pharmaceutics, College of Pharmacy, University of Baghdad, Baghdad, Iraq; 2Department of Pharmaceutics, College of Pharmacy, Uruk University, Baghdad, IraqCorrespondence:
Externí odkaz:
https://doaj.org/article/e7ffcb0560e5441bae0436c3f9dc6cf0
Autor:
Radka Boyuklieva, Plamen Katsarov, Plamen Zagorchev, Silviya Abarova, Asya Hristozova, Bissera Pilicheva
Publikováno v:
Journal of Functional Biomaterials, Vol 15, Iss 11, p 329 (2024)
Elevated brain iron levels are characteristic of many neurodegenerative diseases. As an iron chelator with short biological half-life, deferiprone leads to agranulocytosis and neutropenia with a prolonged therapeutic course. Its inclusion in sustaine
Externí odkaz:
https://doaj.org/article/4c58e53ea74d49ac9f3d2e5f78642724