Zobrazeno 1 - 10
of 1 281
pro vyhledávání: '"bone marrow stromal cell"'
Autor:
Andrew P. Stone, Emma Rand, Gabriel Thornes, Alasdair G. Kay, Amanda L. Barnes, Ian S. Hitchcock, Paul G. Genever
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Bone marrow stromal cells (BMSCs) are highly heterogeneous, which may reflect their diverse biological functions, including tissue maintenance, haematopoietic support and immune control. The current understanding of the mechanisms
Externí odkaz:
https://doaj.org/article/a89c2df4abe04a91b84f62804856201c
Publikováno v:
Journal of Bone Oncology, Vol 47, Iss , Pp 100620- (2024)
Therapy-related myeloid neoplasms (t-MN) are a growing concern due to the continued use of cytotoxic therapies to treat malignancies. Cytotoxic therapies have been shown to drive therapy-induced senescence in normal tissues, including in the bone mar
Externí odkaz:
https://doaj.org/article/5f98a365007545c4bc95e56962baf153
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background Human bone marrow stromal cells (BMSCs) are an easily accessible and expandable progenitor population with the capacity to generate neural cell types in addition to mesoderm. Lineage tracing studies in transgenic animals have indi
Externí odkaz:
https://doaj.org/article/b9e9f9d3025f44f3857e6f02756c692c
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25050- (2024)
Background: Bone-marrow-derived mesenchymal stromal (stem) cells [also called MSC(M)] and their extracellular vesicles (EVs) are considered a potentially innovative form of therapy for traumatic brain injury (TBI). Nevertheless, their application to
Externí odkaz:
https://doaj.org/article/07fc7a3e49d84d708981e0da304d6ce5
Publikováno v:
Organoids, Vol 2, Iss 2, Pp 102-119 (2023)
(1) Background: There are no high-throughput microtissue platforms for generating bone marrow micro-ossicles. Herein, we describe a method for the assembly of arrays of microtissues from bone marrow stromal cells (BMSC) in vitro and their maturation
Externí odkaz:
https://doaj.org/article/286154987fcb43ea9bce252b342a2b2b
Autor:
Zachary Michel, Layne N. Raborn, Tiahna Spencer, Kristen S. Pan, Daniel Martin, Kelly L. Roszko, Yan Wang, Pamela G. Robey, Michael T. Collins, Alison M. Boyce, Luis Fernandez de Castro
Publikováno v:
Cells, Vol 13, Iss 9, p 774 (2024)
Fibrous dysplasia (FD) is a mosaic skeletal disorder caused by somatic activating variants of GNAS encoding for Gαs and leading to excessive cyclic adenosine monophosphate signaling in bone-marrow stromal cells (BMSCs). The effect of Gαs activation
Externí odkaz:
https://doaj.org/article/d85b2c1f4ad94017b9c18b33b85b0365
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
This study aims to present a sustainably releasing system of exosomes-fibrin combinate loaded on tantalum-coating titanium implants. We hope to investigate potential effects of the system on osseointegration between tantalum coating titanium implants
Externí odkaz:
https://doaj.org/article/c3268c6eaa6b44b08ce59da4a4bec601
Akademický článek
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Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-20 (2022)
Abstract Background Recent studies have shown that bone marrow stromal cell-derived exosomes (BMSC-Exos) can be used for tissue repair. However, whether the BMSC-Exos can promote tendon-bone healing after anterior cruciate ligament reconstruction (AC
Externí odkaz:
https://doaj.org/article/1d0812bc7441450297ec66295b490dca
Autor:
María Matamala Montoya, Gijs J. J. van Slobbe, Jung-Chin Chang, Esther A. Zaal, Celia R. Berkers
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Multiple myeloma (MM) is characterized by the clonal expansion of malignant plasma cells in the bone marrow (BM). MM remains an incurable disease, with the majority of patients experiencing multiple relapses from different drugs. The MM tumor microen
Externí odkaz:
https://doaj.org/article/ba54417d87c24cbeb40cd7ca6d4cb4e2