Zobrazeno 1 - 10
of 7 457
pro vyhledávání: '"bone marrow mesenchymal stem cells"'
Autor:
Chongyang Shen, Mingxing Deng, Xiaobao Wang, Xiaoyu Li, Xiongbin Chen, Zhi Gao, Chuncai Li, Yincong Liu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Background Zuogui Wan (ZGW) is a traditional herbal formula used to treat chronic kidney and bone diseases. Previous research has shown that ZGW slows down the aging process of bone marrow mesenchymal stem cells (BMSCs) and improves bone met
Externí odkaz:
https://doaj.org/article/2565066742f140fd899e82e31ae3839a
Autor:
Yingxue Li, Ying Wang, Qian Liu, Shuiying Lv, Yali Wang, Huanhuan Zhang, Qiuhong Zhao, Lei Shang
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Objective Our study focused on the effects and molecular mechanisms of kaempferol, a major active component of Eucommia ulmoides Oliver (EUO), on the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Methods Target mo
Externí odkaz:
https://doaj.org/article/2fc1277b2f0848c1a9ba97fd343a54e7
Publikováno v:
陆军军医大学学报, Vol 46, Iss 19, Pp 2188-2196 (2024)
Objective To explore the role and mechanism of exosomes derived from bone marrow mesenchymal stem cells (BMSCs) overexpressing transglutaminase 2 (TGM2) in lactate-mediated oxidative stress-induced apoptosis in nucleus pulposus cells. Methods Twenty
Externí odkaz:
https://doaj.org/article/016f55e7057e4a98b6a5c31d416b3a15
Autor:
You-li Tan, Shao-hua Ju, Qiang Wang, Rui Zhong, Ji-hai Gao, Ming-jian Wang, Ya-lan Kang, Meng-zhang Xu
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract This study aimed to investigate the effects of Shuanglongjiegu pill (SLJGP) on the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and explore its mechanism based on miR-217/RUNX2 axis. Results found that drug-contai
Externí odkaz:
https://doaj.org/article/33fb09ee72294a81bb2971a39f054adb
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Osteoporosis results from decreased bone mass and disturbed bone structure. Human bone marrow mesenchymal stem cells (hBMSCs) demonstrate robust osteogenic differentiation, a critical process for bone formation. This research was
Externí odkaz:
https://doaj.org/article/7860675801c54d618a82a085aaf0941b
Publikováno v:
陆军军医大学学报, Vol 46, Iss 18, Pp 2057-2068 (2024)
Objective To develop an effective method for delivering VEGF and CD47 double-modified exosomes to treat renal damage induced by heat stroke so as to reduce and repair renal damage. Methods A plasmid fusion-expressing VEGF and CD47 targeting renal inj
Externí odkaz:
https://doaj.org/article/23492e4caafd44dd82c7fb1b5919968b
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-26 (2024)
Abstract To assess the efficacy of a novel 3D biomimetic hydrogel scaffold with immunomodulatory properties in promoting fracture healing. Immunomodulatory scaffolds were used in cell experiments, osteotomy mice treatment, and single-cell transcripto
Externí odkaz:
https://doaj.org/article/3a7adfbbdf6549bd8f4c3a94345bbf6c
Autor:
LIU Huan, WU Xi
Publikováno v:
口腔疾病防治, Vol 32, Iss 9, Pp 674-683 (2024)
Objective To study the effect of the combinational use of miR-34a-functionalized Bio-Oss® bone powder with transglutaminase crosslinked gelatin (Col-Tgel) on the osteoblastic differentiation of bone marrow mesenchymal stem cells (BMSCs) and bone def
Externí odkaz:
https://doaj.org/article/cdcdbda7a063459ab7b4858f5b06a2d0
Autor:
Mingzhu Deng, Feifei Gao, Tianfeng Liu, Weiqiang Zhan, Juanhua Quan, Ziquan Zhao, Xuyang Wu, Zhuolan Zhong, Hong Zheng, Jiaqi Chu
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Bone defects, resulting from substantial bone loss that exceeds the natural self-healing capacity, pose significant challenges to current therapeutic approaches due to various limitations. In the quest for alternative therapeutic
Externí odkaz:
https://doaj.org/article/d17d789a5bf14e58b3d52c9e5178df59
Autor:
Linfeng Wang, Changbiao Guan, Tao Zhang, Yongchun Zhou, Yuqian Liu, Jianzhong Hu, Daqi Xu, Hongbin Lu
Publikováno v:
Journal of Orthopaedic Translation, Vol 47, Iss , Pp 87-96 (2024)
Background: Bone marrow mesenchymal stem cells (BMSCs) have immense potential in applications for the enhancement of tendon-bone (T-B) healing. Recently, it has been well-reported that skeletal stem cells (SSCs) could induce bone and cartilage regene
Externí odkaz:
https://doaj.org/article/3c99069b9e644d0a84e82cc883d49fbd