Zobrazeno 1 - 10
of 5 349
pro vyhledávání: '"bmp-2"'
Autor:
Xue-Xue Zhu, Xin-Yu Meng, Guo Chen, Jia-Bao Su, Xiao Fu, An-Jing Xu, Yao Liu, Xiao-Hui Hou, Hong-Bo Qiu, Qing-Yi Sun, Jin-Yi Hu, Zhuo-Lin Lv, Hai-Jian Sun, Hai-Bin Jiang, Zhi-Jun Han, Jian Zhu, Qing-Bo Lu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Vascular calcification (VC) arises from the accumulation of calcium salts in the intimal or tunica media layer of the aorta, contributing to higher risk of cardiovascular events and mortality. Despite this, the mechanisms driving VC remain i
Externí odkaz:
https://doaj.org/article/2cca5f0c8f9d41b9905c546a52e4c2bf
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract In this study, we developed scaffolds materials with microspheres to form a double sustained release system.Chitosan/nano-hydroxyapatite (CS-HA) was used as a drug carrier to construct a sustained-release system for Bone morphogenetic protei
Externí odkaz:
https://doaj.org/article/1b9c75492fde46439427ad4da2091391
Autor:
Jai-Hong Cheng, Shun-Wun Jhan, Po-Cheng Chen, Shan-Ling Hsu, Ching-Jen Wang, Daniel Moya, Yi-No Wu, Chien-Yiu Huang, Wen-Yi Chou, Kuan-Ting Wu
Publikováno v:
Bone & Joint Research, Vol 13, Iss 7, Pp 342-352 (2024)
Aims: To explore the efficacy of extracorporeal shockwave therapy (ESWT) in the treatment of osteochondral defect (OCD), and its effects on the levels of transforming growth factor (TGF)-β, bone morphogenetic protein (BMP)-2, -3, -4, -5, and -7 in t
Externí odkaz:
https://doaj.org/article/1c3851d7f3ba4a02bf72ee6888932f31
Autor:
Yu Zhao, Wenjiang Huang, Delin Ma, Qichao Zhao, Xiaxin Qiu, Jinying Liu, Chuanliang Feng, Shaokang Guan
Publikováno v:
Materials & Design, Vol 247, Iss , Pp 113372- (2024)
Biomedical magnesium alloys (Mg) are often considered potential metallic materials for bone repair scaffolds due to their excellent biomechanical properties, biocompatibility, and biodegradability. However, their rapid degradation behavior is insuffi
Externí odkaz:
https://doaj.org/article/d0a7bcfa273e49219e039e3dc1af19d2
Autor:
Lucas Ritschl, Pia Schilling, Annette Wittmer, Annerose Serr, Hagen Schmal, Michael Seidenstuecker
Publikováno v:
BMC Biotechnology, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Antibiotic-containing carrier systems are one option that offers the advantage of releasing active ingredients over a longer period of time. In vitro sustained drug release from a carrier system consisting of microporous β-TCP ce
Externí odkaz:
https://doaj.org/article/13a6554740b64817907fe18774dfab00
Autor:
Valeriya Sergeevna Kuznetsova, Andrey Vyacheslavovich Vasilyev, Tatiana Borisovna Bukharova, Irina Alekseevna Nedorubova, Dmitry Vadimovich Goldshtein, Vladimir Karpovich Popov, Anatoly Alekseevich Kulakov
Publikováno v:
Saudi Dental Journal, Vol 36, Iss 6, Pp 855-862 (2024)
The restoration of bone defects resulting from tooth loss, periodontal disease, severe trauma, tumour resection and congenital malformations is a crucial task in dentistry and maxillofacial surgery. Growth factor- and gene-activated bone graft substi
Externí odkaz:
https://doaj.org/article/a90ff4b16b8c4a1bad41088c0fd55605
Autor:
Amelie Deluca, Andrea Wagner, Patrick Heimel, Christian Deininger, Florian Wichlas, Heinz Redl, Eva Rohde, Herbert Tempfer, Mario Gimona, Andreas Traweger
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Background The aim of this study was to evaluate potential synergistic effects of a single, local application of human umbilical cord MSC-derived sEVs in combination with a low dose of recombinant human rhBMP-2 to promote the regeneration of
Externí odkaz:
https://doaj.org/article/7d2ff81e56f648e2ad983488d3bcd62f
Autor:
Qingxu Song, Dianwei Wang, Haoyu Li, Zongliang Wang, Songjia Sun, Zhenyu Wang, Yi Liu, Sien Lin, Gang Li, Shaokun Zhang, Peibiao Zhang
Publikováno v:
Bioactive Materials, Vol 32, Iss , Pp 304-318 (2024)
Using bone tissue engineering strategies to achieve bone defect repair is a promising modality. However, the repair process outcomes are often unsatisfactory. Here we properly designed a multi-functional microsphere system, which could deliver bioact
Externí odkaz:
https://doaj.org/article/1a6a16a641e046ab8943086514d8d18a
Autor:
Hee Eun Kim, Hyeon Jin Ju, Shina Kim, Young Hun Kim, Soyeon Lee, Sangdun Choi, Hyun C. Yoon, Hak Soo Choi, Moon Suk Kim
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101070- (2024)
Endogenous stem cell-driven in situ bone tissue formation has recently garnered increasing attention. Therefore, our study sought to refine methods to enhance the migration and subsequent osteogenic differentiation of these cells. Our innovative appr
Externí odkaz:
https://doaj.org/article/a126dda28c4646cbb1f6ce8817dc4167
Publikováno v:
Frontiers in Materials, Vol 11 (2024)
Treatment of large and complex irregular bone defects is a major clinical challenge in orthopedic surgery. The current treatment includes bone transportation using the Ilizarov technique and bone cement repair using the Masquelet technique, but they
Externí odkaz:
https://doaj.org/article/5d1cf3ea4a204c39acb261d3a769783a