Zobrazeno 1 - 10
of 74
pro vyhledávání: '"blood cell traits"'
Autor:
Jinghao Liang, Xinyi Zhou, Yijian Lin, Hongming Yin, Yuanqing Liu, Zixian Xie, Hongmiao Lin, Tongtong Wu, Xinrong Zhang, Zhaofeng Tan, Ziqiu Cheng, Weiqiang Yin, Zhihua Guo, Wenzhe Chen
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Research on the link between blood cell traits and cancer risk has gained significant attention. Traditional epidemiological and cell biology studies, have identified correlations between blood traits and cancer risks. These findi
Externí odkaz:
https://doaj.org/article/bf4f3e10f0844211a2afcce7f3b09edb
Autor:
Fangyuan Zhang, Feiyu Jiang, Ziqin Yao, Hongbin Luo, Shoufang Xu, Yingying Zhang, Xinhui Wang, Zhiwei Liu
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundObservational studies have found associations between blood cell traits and inflammatory bowel diseases (IBDs), whereas the causality and dose-effect relationships are still undetermined.MethodsTwo-sample Mendelian randomization (MR) analys
Externí odkaz:
https://doaj.org/article/7489f4b60a1642319acdc17f878bf144
Akademický článek
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Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Importance: Glaucoma is the second leading cause of blindness in the world. The causal direction and magnitude of the association between blood cell traits and glaucoma is uncertain because of the susceptibility of observational studies to confoundin
Externí odkaz:
https://doaj.org/article/e1db04c2092b48eda26885312435fb8c
The shared genetic landscape of blood cell traits and risk of neurological and psychiatric disorders
Autor:
Yuanhao Yang, Yuan Zhou, Dale R. Nyholt, Chloe X. Yap, Rudolph K. Tannenberg, Ying Wang, Yang Wu, Zhihong Zhu, Bruce V. Taylor, Jacob Gratten
Publikováno v:
Cell Genomics, Vol 3, Iss 2, Pp 100249- (2023)
Summary: Phenotypic associations have been reported between blood cell traits (BCTs) and a range of neurological and psychiatric disorders (NPDs), but in most cases, it remains unclear whether these associations have a genetic basis and, if so, to wh
Externí odkaz:
https://doaj.org/article/415bb40f24824181bd46d65c3f20bb08
Akademický článek
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Autor:
Chani J. Hodonsky, Antoine R. Baldassari, Stephanie A. Bien, Laura M. Raffield, Heather M. Highland, Colleen M. Sitlani, Genevieve L. Wojcik, Ran Tao, Marielisa Graff, Weihong Tang, Bharat Thyagarajan, Steve Buyske, Myriam Fornage, Lucia A. Hindorff, Yun Li, Danyu Lin, Alex P. Reiner, Kari E. North, Ruth J. F. Loos, Charles Kooperberg, Christy L. Avery
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Quantitative red blood cell (RBC) traits are highly polygenic clinically relevant traits, with approximately 500 reported GWAS loci. The majority of RBC trait GWAS have been performed in European- or East Asian-ancestry population
Externí odkaz:
https://doaj.org/article/6ff5554a9a9846dab897a9bbaf6c30b9
Autor:
Quan Sun, Cheynna A. Crowley, Le Huang, Jia Wen, Jiawen Chen, Erik L. Bao, Paul L. Auer, Guillaume Lettre, Alexander P. Reiner, Vijay G. Sankaran, Laura M. Raffield, Yun Li
Publikováno v:
HGG Advances, Vol 3, Iss 1, Pp 100063- (2022)
Summary: Genome-wide association studies (GWASs) have identified hundreds of thousands of genetic variants associated with complex diseases and traits. However, most variants are noncoding and not clearly linked to genes, making it challenging to int
Externí odkaz:
https://doaj.org/article/8abda8675f2a4da690ff7e5a66dff133
Autor:
Opeyemi Soremekun, Chisom Soremekun, Tafadzwa Machipisa, Mahmoud Soliman, Oyekanmi Nashiru, Tinashe Chikowore, Segun Fatumo
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Background: White blood cell (WBC) traits and their subtypes such as basophil count (Bas), eosinophil count (Eos), lymphocyte count (Lym), monocyte count (Mon), and neutrophil counts (Neu) are known to be associated with diseases such as stroke, peri
Externí odkaz:
https://doaj.org/article/5308e30dbb4d4b22b582bcaa719452b0
Akademický článek
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