Zobrazeno 1 - 10
of 115
pro vyhledávání: '"blood–brain barrier model"'
Autor:
Léa Gaume, Hélène Chabrolles, Maxime Bisseux, Igor Lopez-Coqueiro, Lucie Dehouck, Audrey Mirand, Cécile Henquell, Fabien Gosselet, Christine Archimbaud, Jean-Luc Bailly
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Enterovirus A71 (EV-A71) is associated with neurological conditions such as acute meningitis and encephalitis. The virus is detected in the bloodstream, and high blood viral loads are associated with central nervous system (CNS) manifestatio
Externí odkaz:
https://doaj.org/article/e9a1f0fdf2174ad882d99b9c407f3dd3
Autor:
Yajuan Shi, Hyosung Kim, Catherine A. Hamann, Elizabeth M. Rhea, Jonathan M. Brunger, Ethan S. Lippmann
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background The hormone leptin exerts its function in the brain to reduce food intake and increase energy expenditure to prevent obesity. However, most obese subjects reflect the resistance to leptin even with elevated serum leptin. Consideri
Externí odkaz:
https://doaj.org/article/a535bb02a28d4961be69eb3aff4992b3
Autor:
Yucheng Shang, Marie Piantino, Jinfeng Zeng, Fiona Louis, Zhengtian Xie, Tomomi Furihata, Michiya Matsusaki
Publikováno v:
Materials Today Bio, Vol 21, Iss , Pp 100714- (2023)
The blood-brain barrier (BBB) is a type of capillary network characterized by a highly selective barrier, which restricts the transport of substances between the blood and nervous system. Numerous in vitro models of the BBB have been developed for dr
Externí odkaz:
https://doaj.org/article/764b86e382124a69ba382358a5fd1523
Akademický článek
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Autor:
Yamir Islam, Andrew G. Leach, Jayden Smith, Stefano Pluchino, Christopher R. Coxon, Muttuswamy Sivakumaran, James Downing, Amos A. Fatokun, Meritxell Teixidò, Touraj Ehtezazi
Publikováno v:
Advanced Science, Vol 8, Iss 11, Pp n/a-n/a (2021)
Abstract The prevalence of neurological/neurodegenerative diseases, such as Alzheimer's disease is known to be increasing due to an aging population and is anticipated to further grow in the decades ahead. The treatment of brain diseases is challengi
Externí odkaz:
https://doaj.org/article/3eafd854a90a43b892f923af6f962f04
Autor:
Judie B. Alimonti, Maria Ribecco-Lutkiewicz, Caroline Sodja, Anna Jezierski, Danica B. Stanimirovic, Qing Liu, Arsalan S. Haqqani, Wayne Conlan, Mahmud Bani-Yaghoub
Publikováno v:
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-9 (2018)
Abstract Zika virus (ZIKV) is a flavivirus that is highly neurotropic causing congenital abnormalities and neurological damage to the central nervous systems (CNS). In this study, we used a human induced pluripotent stem cell (iPSC)-derived blood bra
Externí odkaz:
https://doaj.org/article/f00bc4d9034b409bac309b87cd64ce82
Publikováno v:
Viruses, Vol 13, Iss 6, p 1004 (2021)
Chemodietary agents are emerging as promising adjuvant therapies in treating various disease conditions. However, there are no adjuvant therapies available to minimize the neurotoxicity of currently existing antiretroviral drugs (ARVs). In this study
Externí odkaz:
https://doaj.org/article/17c79d4f72d641cb8461e46a4a630f32
Autor:
Alla B. Salmina, Ekaterina V. Kharitonova, Yana V. Gorina, Elena A. Teplyashina, Natalia A. Malinovskaya, Elena D. Khilazheva, Angelina I. Mosyagina, Andrey V. Morgun, Anton N. Shuvaev, Vladimir V. Salmin, Olga L. Lopatina, Yulia K. Komleva
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4661 (2021)
Pathophysiology of chronic neurodegeneration is mainly based on complex mechanisms related to aberrant signal transduction, excitation/inhibition imbalance, excitotoxicity, synaptic dysfunction, oxidative stress, proteotoxicity and protein misfolding
Externí odkaz:
https://doaj.org/article/3910eea9dafd41ff867ace16ac671093
Akademický článek
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