Zobrazeno 1 - 10
of 606
pro vyhledávání: '"blockade therapy"'
Autor:
Mengjie Ye, Junfeng Hu, Linlin Han, Hengbo Zhang, Peng Xue, Yuejun Kang, Shuang Bai, Zhigang Xu
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract Chemotherapy‐based combination regimens are recommended as first‐line treatment for colorectal cancer. However, multidrug resistance (MDR) and limited drug infiltration in tumor microenvironment remain critical challenges. Herein, a pH/r
Externí odkaz:
https://doaj.org/article/34538943ed034f50af12ee015bacb586
Autor:
Annunziata Gloghini, Antonino Carbone
Publikováno v:
Hemato, Vol 5, Iss 2, Pp 199-207 (2024)
Classic Hodgkin lymphoma (cHL) is a B-cell lymphoma in which tumour cells, the so-called Hodgkin Reed–Sternberg (HRS) cells, are admixed with non-malignant cell types that are a functional part of the disease. Immune cells, fibroblasts, specialised
Externí odkaz:
https://doaj.org/article/f3d20ae22ad84c09bd19f29d4e5a32da
Autor:
Qiao-xin Lin, Wen-wen Song, Wen-xia Xie, Yi-ting Deng, Yan-na Gong, Yi-ru Liu, Yi Tian, Wen-ya Zhao, Ling Tian, Dian-na Gu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 59, Iss , Pp 101077- (2025)
Objective: Anti-angiogenic therapy and immune checkpoint blockade therapy are currently important treatments for non-small cell lung cancer. However, the combined use of the two therapies is controversial, and few studies have investigated the effect
Externí odkaz:
https://doaj.org/article/74e44febb7d7493788a3bb40b1c0df5a
Publikováno v:
生物医学转化, Vol 5, Iss 2, Pp 67-71-90 (2024)
CD8+ T cells are the primary mediators of antigen-specific immune responses, with their functional states finely regulated by molecular mechanisms, playing a crucial role in tumor immunity. In recent years, CD8+ T-cell-based cellular therapies (e.g.,
Externí odkaz:
https://doaj.org/article/8c2c6d1253f349b99408ec83a2f86acb
Autor:
Wenjuan Mei, Ying Dong, Yan Gu, Anil Kapoor, Xiaozeng Lin, Yingying Su, Sandra Vega Neira, Damu Tang
Publikováno v:
Journal of Advanced Research, Vol 54, Iss , Pp 195-210 (2023)
Introduction: IQGAP3 possesses oncogenic actions; its impact on prostate cancer (PC) remains unclear. Objective: We will investigate IQGAP3′s association with PC progression, key mechanisms, prognosis, and immune evasion. Methods: IQGAP3 expression
Externí odkaz:
https://doaj.org/article/485ac59ffab84301b40eadee2d3799ec
Publikováno v:
International Journal of General Medicine, Vol Volume 16, Pp 5527-5548 (2023)
Shaoping Wu,1 Junnan Chen,1 Enmin Huang,2– 4 Yongfa Zhang1 1Department of Anesthesiology, the Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, People’s Republic of China; 2Biomedical Innovation Center, the Sixth
Externí odkaz:
https://doaj.org/article/9c4f1e4a8a75425cbb5c1db57bceea63
Publikováno v:
BioMedInformatics, Vol 3, Iss 4, Pp 1060-1070 (2023)
Lung cancer is responsible for the most cancer deaths worldwide, with non-small-cell lung cancer (NSCLC) making up 80% of cases. Some genetic factors leading to NSCLC development include genetic mutations and Programmed Cell Death Ligand 1 (PD-L1) ex
Externí odkaz:
https://doaj.org/article/c43c154047c249c58a4e5139609835a6
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2152 (2024)
Background: Although immunotherapy has shown potential in cancer treatment, current immunotherapeutics for bladder cancer are limited by a low response rate. Therefore, it is necessary to investigate other suitable immunotherapeutic targets and strat
Externí odkaz:
https://doaj.org/article/8db267586fa24262b4b3f9c641417b78
Autor:
Songlin Liu, Haiyang Wang, Xinzhe Shao, Haonan Chen, Shushu Chao, Yanyan Zhang, Zhaoju Gao, Qingqiang Yao, Pingping Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-24 (2023)
Abstract In recent years, cancer immunotherapy has emerged as an exciting cancer treatment. Immune checkpoint blockade brings new opportunities for more researchers and clinicians. Programmed cell death receptor-1 (PD-1) is a widely studied immune ch
Externí odkaz:
https://doaj.org/article/0be0a5d6e8f94533a3d3b7fb608e0db0
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
We present an exceptional case of a 53-year-old female, initially misdiagnosed with fulminant myocarditis, but later correctly diagnosed with pheochromocytoma. The presentation of the patient included a spectrum of symptoms such as headache, chest di
Externí odkaz:
https://doaj.org/article/b1dc2ecf5fbe4be1bd9a83e146bbf954