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Akademický článek

First Report of Carbapenem-Resistant Klebsiella michiganensis Co-Harboring blaKPC-2 and TmexCD2-ToprJ2 Isolated from Wastewater at a Tertiary Hospital in Beijing

Autor: Long J, Chen J, Yuan Y, Yang S, Xie X, Wu X, Liu Y, Guo J, Chen Y, Wang C, Liu X

Publikováno v: Infection and Drug Resistance, Vol Volume 17, Pp 5117-5128 (2024)

Jiamin Long,1,2,* Jiali Chen,3,* Yue Yuan,4,* Shaozhen Yang,5,* Xinya Xie,1,2 Xuelian Wu,1,2 Yuan Liu,1,2 Jinpeng Guo,2 Yong Chen,1,2 Changjun Wang,1,2 Xiong Liu2 1School of Public Health, China Medical University, Shenyang, 110122, P

Externí odkaz: https://doaj.org/article/d58b5156c37d44f9988a72cde7e302f6

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Akademický článek

Genomic Characteristics of a Carbapenem-Resistant Klebsiella pneumoniae Co-Carrying blaNDM-5 and blaKPC-2 Capsular Type KL25 Recovered from a County Level Hospital in China

Autor: Fang Y, Jin J, Peng M, Xu L, Gu L, Bao D, Zhang Q, Jin K

Publikováno v: Infection and Drug Resistance, Vol Volume 17, Pp 3979-3987 (2024)

Yuanzhong Fang,1 Juan Jin,1 Minfei Peng,2 Lidong Xu,1 Linyuan Gu,1 Danni Bao,3 Qiuying Zhang,4 Kainan Jin5 1Department of Clinical Laboratory, Hangzhou Linping District Women & Children Hospital, Hangzhou, Zhejiang, People’s Republic of China; 2Dep

Externí odkaz: https://doaj.org/article/099a514e67d04de8af44fb9815f98909

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Akademický článek

Replicon-Based Typing About IncG Plasmids and Molecular Characterization of Five IncG Plasmids Carrying Carbapenem Resistance Gene blaKPC-2

Autor: Guo H, Luo J, Chen S, Yu T, Mu X, Chen F, Lu X, He J, Zheng Y, Bao C, Wang P, Yin Z, Li B

Publikováno v: Infection and Drug Resistance, Vol Volume 17, Pp 2987-2999 (2024)

Huiqian Guo,1,2,* Jing Luo,1,3,* Suming Chen,1 Ting Yu,4 Xiaofei Mu,4 Fangzhou Chen,4 Xiuhui Lu,4 Jiaqi He,4 Yali Zheng,4 Chunmei Bao,2 Peng Wang,4 Zhe Yin,4 Boan Li1– 3 1Department of Clinical Laboratory, the Fifth Medical Center of PLA Ge

Externí odkaz: https://doaj.org/article/27e7323d88e34ce0998b754383894ee2

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Akademický článek

Genomic and Phenotypic Analysis of blaKPC-2 Associated Carbapenem Resistance in Klebsiella aerogenes: Insights into Clonal Spread and Resistance Mechanisms Across Hospital Departments in Beijing

Autor: Jin H, Yan Z, Ge X, Wang Q, Wang H, Du X, Liu H, Yang C, Xiang Y, Tian S, Qiu S, Zhou Y

Publikováno v: Infection and Drug Resistance, Vol Volume 17, Pp 2735-2749 (2024)

Hang Jin,1,2,* Zhongqiang Yan,3,* Xin Ge,4,* Qi Wang,2 Hui Wang,2 Xinying Du,2 Hongbo Liu,2 Chaojie Yang,2 Ying Xiang,2 Sai Tian,2 Shaofu Qiu,1,2 Yu Zhou5 1School of Public Health, Zhengzhou University, Zhengzhou, People’s Republic of C

Externí odkaz: https://doaj.org/article/e6b0d84e4a3f4ec4aefcb2947d410b69

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Akademický článek

Molecular mechanisms responsible KPC-135-mediated resistance to ceftazidime-avibactam in ST11-K47 hypervirulent Klebsiella pneumoniae

Autor: Qingyu Shi, Siquan Shen, Chengkang Tang, Li Ding, Yan Guo, Yang Yang, Shi Wu, Renru Han, Dandan Yin, Fupin Hu

Publikováno v: Emerging Microbes and Infections, Vol 13, Iss 1 (2024)

Ceftazidime-avibactam resistance attributable to the blaKPC-2 gene mutation is increasingly documented in clinical settings. In this study, we characterized the mechanisms leading to the development of ceftazidime-avibactam resistance in ST11-K47 hyp

Externí odkaz: https://doaj.org/article/6912819c762c49e2959da541d64b54e7

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Akademický článek

Genomic characterization of a blaKPC-2–producing IncM2 plasmid harboring transposon ΔTn6296 in Klebsiella michiganensis

Autor: Jian-Mei Song, Hu-Bo Long, Mei Ye, Bao-Rui Yang, Guang-Juan Wu, Hong-Chun He, Jun-Ling Wang, Hong-Wei Li, Xiao-Gang Li, De-Yao Deng, Bo Li, Wen-Li Yuan

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)

Klebsiella michiganensis is an emerging hospital-acquired bacterial pathogen, particularly strains harboring plasmid-mediated carbapenemase genes. Here, we recovered and characterized a multidrug-resistant strain, blaKPC-2–producing Klebsiella mich

Externí odkaz: https://doaj.org/article/7c36ac1dea2c4f179f571a59e6281eeb

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Akademický článek

First report of ISKpn26 element mediating mgrB gene disruption in the ST1 colistin- and carbapenem-resistant Klebsiella pneumoniae cluster isolated from a patient with chest infection

Autor: Xiaosi Li, Siquan Shen, Yan Feng, Heping Shen, Fupin Hu, Xiaoyan Wu

Publikováno v: Microbiology Spectrum, Vol 12, Iss 11 (2024)

ABSTRACT Colistin is used as a last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). However, colistin resistance in Klebsiella pneumoniae is increasingly reported worldwide. This study aims to investigate the instrumental role

Externí odkaz: https://doaj.org/article/bb6c6a616ff9458585a18413c69c8072

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Akademický článek

Coexistence of a novel chromosomal integrative and mobilizable element Tn7548 with two blaKPC-2-carrying plasmids in a multidrug-resistant Aeromonas hydrophila strain K522 from China

Autor: Ying Jing, Sufei Yu, Zhaolun Li, Jie Ma, Luwei Wang, Lianhua Yu, Zhiwei Song, Huimin Chen, Zhenghai Wu, Xinhua Luo

Publikováno v: Journal of Global Antimicrobial Resistance, Vol 37, Iss , Pp 157-164 (2024)

ABSTRACT: Objectives: Herein, we detected one multidrug-resistant Aeromonas hydrophila strain K522 co-carrying two blaKPC-2 genes together with a novel chromosomal integrative and mobilizable element (IME) Tn7548 from China. To reveal the genetic cha

Externí odkaz: https://doaj.org/article/fc44c3a7a9774f35a1aae6b6b1120d48

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Akademický článek

Emergence of a clinical Klebsiella pneumoniae harboring an acrAB-tolC in chromosome and carrying the two repetitive tandem core structures for blaKPC-2 and blaCTX-M-65 in a plasmid

Autor: Long He, Wenji Wang, Liman Ma, Dongguo Wang, Shanshan Long

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)

ObjectiveThe emergence of clinical Klebsiella pneumoniae strains harboring acrAB-tolC genes in the chromosome, along with the presence of two repetitive tandem core structures for blaKPC-2 and blaCTX-M-65 genes on a plasmid, has presented a significa

Externí odkaz: https://doaj.org/article/8185b44bad794e519df4c4472074bc83

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Akademický článek

Emergency of the plasmid co-carrying blaKPC-2 and blaNDM-1 genes in carbapenem-resistant hypervirulent Klebsiella pneumoniae

Autor: Shijun Sun, Meng Cai, Qi Wang, Shuyi Wang, Lin Zhang, Hui Wang

Publikováno v: Journal of Global Antimicrobial Resistance, Vol 36, Iss , Pp 26-32 (2024)

Background: Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a prevalent issue in China, with its spread primarily attributed to the presence of the plasmid-borne carbapenemase genes, blaKPC and blaNDM. However, instances of plasmids containing b

Externí odkaz: https://doaj.org/article/18a6a916848c4ae686358828bdaa2fcc

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