Zobrazeno 1 - 10
of 182
pro vyhledávání: '"bisulphite sequencing"'
Autor:
Olivia Strunge Meyer, Mikkel Meyer Andersen, Claus Børsting, Niels Morling, Hans Christian Wulf, Peter Alshede Philipsen, Catharina Margrethe Lerche, Jeppe Dyrberg Andersen
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Until recently, studying the murine methylome was restricted to sequencing-based methods. In this study we compared the global DNA methylation levels of hairless mouse epidermis using the recently released Infinium Mouse Methylation BeadChip from Ill
Externí odkaz:
https://doaj.org/article/0c87cf2a8f84474b99865c0d25c65d4e
Autor:
Essi Laajala, Viivi Halla-aho, Toni Grönroos, Ubaid Ullah Kalim, Mari Vähä-Mäkilä, Mirja Nurmio, Henna Kallionpää, Niina Lietzén, Juha Mykkänen, Omid Rasool, Jorma Toppari, Matej Orešič, Mikael Knip, Riikka Lund, Riitta Lahesmaa, Harri Lähdesmäki
Publikováno v:
Epigenetics, Vol 17, Iss 12, Pp 1608-1627 (2022)
DNA methylation patterns are largely established in-utero and might mediate the impacts of in-utero conditions on later health outcomes. Associations between perinatal DNA methylation marks and pregnancy-related variables, such as maternal age and ge
Externí odkaz:
https://doaj.org/article/667134eacf774c6e931b0432d4c2ea31
Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers
Autor:
Marina Laplana, Matthias Bieg, Christian Faltus, Svitlana Melnik, Olga Bogatyrova, Zuguang Gu, Thomas Muley, Michael Meister, Hendrik Dienemann, Esther Herpel, Christopher I. Amos, Matthias Schlesner, Roland Eils, Christoph Plass, Angela Risch
Publikováno v:
Epigenetics, Vol 17, Iss 2, Pp 117-132 (2022)
Genome-wide association studies (GWAS) have identified SNPs linked with lung cancer risk. Our aim was to discover the genes, non-coding RNAs, and regulatory elements within GWAS-identified risk regions that are deregulated in non-small cell lung carc
Externí odkaz:
https://doaj.org/article/cb891c49a1b84bcea2c61c7b01623809
Autor:
Chenglong Yu, Pierre-Antoine Dugué, James G. Dowty, Fleur Hammet, JiHoon E. Joo, Ee Ming Wong, Mahnaz Hosseinpour, Graham G. Giles, John L. Hopper, Tu Nguyen-Dumont, Robert J. MacInnis, Melissa C. Southey
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)
Abstract Objective In previous studies using Illumina Infinium methylation arrays, we have identified DNA methylation marks associated with cancer predisposition and progression. In the present study, we have sought to find appropriate technology to
Externí odkaz:
https://doaj.org/article/90488fe9a95a45dcbc86146886e81e31
Akademický článek
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Autor:
Jonathan A. Heiss, Kasey J. Brennan, Andrea A. Baccarelli, Martha M. Téllez-Rojo, Guadalupe Estrada-Gutiérrez, Robert O. Wright, Allan C. Just
Publikováno v:
Epigenetics, Vol 15, Iss 1-2, Pp 174-182 (2020)
DNA methylation microarrays have been the platform of choice for epigenome-wide association studies in epidemiology, but declining costs have rendered targeted bisulphite sequencing a feasible alternative. Nonetheless, the literature for researchers
Externí odkaz:
https://doaj.org/article/46d32e8b908a4cc788ce50d539d49897
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Following their production in the testis, spermatozoa enter the epididymis where they gain their motility and fertilizing abilities. This post-testicular maturation coincides with sperm epigenetic profile changes that influence progeny outcome. While
Externí odkaz:
https://doaj.org/article/73b5a60b04ff4494afd75f5de7f42b10
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background The degradation of epigenetic control with age is associated with progressive diseases of ageing, including cancers, immunodeficiency and diabetes. Reduced caloric intake slows the effects of ageing and age-related disease in vert
Externí odkaz:
https://doaj.org/article/81e46b9abc9a4ed9a8437fe2fda35bfd
Autor:
Shalima S. Nair, Phuc-Loi Luu, Wenjia Qu, Madhavi Maddugoda, Lily Huschtscha, Roger Reddel, Georgia Chenevix-Trench, Martina Toso, James G. Kench, Lisa G. Horvath, Vanessa M. Hayes, Phillip D. Stricker, Timothy P. Hughes, Deborah L. White, John E. J. Rasko, Justin J.-L. Wong, Susan J. Clark
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-20 (2018)
Abstract Background Comprehensive genome-wide DNA methylation profiling is critical to gain insights into epigenetic reprogramming during development and disease processes. Among the different genome-wide DNA methylation technologies, whole genome bi
Externí odkaz:
https://doaj.org/article/4b0c244e8fac47f18cdf2eed2689bdf4
Autor:
Khushboo Gupta, Rohini Garg
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 3; Pages: 1863
DNA methylation is one of the epigenetic mechanisms that govern gene regulation in response to abiotic stress in plants. Here, we analyzed the role of epigenetic variations by exploring global DNA methylation and integrating it with differential gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ac07cc031f8045f9cd483dcd6556c5