Zobrazeno 1 - 10
of 7 873
pro vyhledávání: '"bisulfite sequencing"'
Autor:
Hongxiang Fu, Harry Pickering, Liudmilla Rubbi, Ted M. Ross, Wanding Zhou, Elaine F. Reed, Matteo Pellegrini
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background The effect of vaccination on the epigenome remains poorly characterized. In previous research, we identified an association between seroprotection against influenza and DNA methylation at sites associated with the RIG-1 signaling
Externí odkaz:
https://doaj.org/article/299d90b0d0a0472f87d41bcd52d6438d
Autor:
Kero Guynes, Luke A. Sarre, Allan M. Carrillo-Baltodano, Billie E. Davies, Lan Xu, Yan Liang, Francisco M. Martín-Zamora, Paul J. Hurd, Alex de Mendoza, José M. Martín-Durán
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-29 (2024)
Abstract Background DNA methylation in the form of 5-methylcytosine (5mC) is the most abundant base modification in animals. However, 5mC levels vary widely across taxa. While vertebrate genomes are hypermethylated, in most invertebrates, 5mC concent
Externí odkaz:
https://doaj.org/article/20a431888cef488aa839a5075a92be08
Publikováno v:
BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Objectivies Pregnancy induced hypertension (PIH) syndrome is a disease that unique to pregnant women and is associated with elevated risk of offspring cardiovascular diseases (CVDs) and neurodevelopmental disorders in their kids. Previous re
Externí odkaz:
https://doaj.org/article/07db3e8de0d94c20b71d539f74811fce
Autor:
Xiao-Long Cui, Ji Nie, Houxiang Zhu, Krissana Kowitwanich, Alana V. Beadell, Diana C. West-Szymanski, Zhou Zhang, Urszula Dougherty, Akushika Kwesi, Zifeng Deng, Yan Li, Danqing Meng, Kevin Roggin, Teresa Barry, Ryan Owyang, Ben Fefferman, Chang Zeng, Lu Gao, Carolyn W. T. Zhao, Yuri Malina, Jiangbo Wei, Melanie Weigert, Wenjun Kang, Ajay Goel, Brian C.-H. Chiu, Marc Bissonnette, Wei Zhang, Mengjie Chen, Chuan He
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Methylation-based liquid biopsies show promises in detecting cancer using circulating cell-free DNA; however, current limitations impede clinical application. Most assays necessitate substantial DNA inputs, posing challenges. Additionally, u
Externí odkaz:
https://doaj.org/article/5bb50822efdf457baaf29b14934cc113
Autor:
Yance Feng, Fei Gao
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Bisulfite sequencing (BS-Seq) is a fundamental technique for characterizing DNA methylation profiles. Genotype calling from bisulfite-converted BS-Seq data allows allele-specific methylation analysis and the concurrent exploration
Externí odkaz:
https://doaj.org/article/2349dac364e44697a2517e80cd671e97
Autor:
О. Yu. Vasilyeva, E. N. Tolmacheva, A. E. Dmitriev, Ya. A. Darkova, E. A. Sazhenova, T. V. Nikitina, I. N. Lebedev, S. A. Vasilyev
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 28, Iss 2, Pp 198-203 (2024)
In humans, aneuploidy is incompatible with the birth of healthy children and mainly leads to the death of embryos in the early stages of development in the first trimester of pregnancy. Trisomy 16 is the most common aneup loidy among spontaneous abor
Externí odkaz:
https://doaj.org/article/2ac1243c5f7443e7a449662c9762763c
Autor:
Konstantin Yuditskiy, Igor Bezdvornykh, Anastasiya Kazantseva, Alexander Kanapin, Anastasia Samsonova
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Bisulfite sequencing detects and quantifies DNA methylation patterns, contributing to our understanding of gene expression regulation, genome stability maintenance, conservation of epigenetic mechanisms across divergent taxa, epig
Externí odkaz:
https://doaj.org/article/c686a72ebfe34d338196a020d3e7eade
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Rubber tree (Hevea brasiliensis) is reproduced by bud grafting for commercial planting, but significant intraclonal variations exist in bud-grafted clones. DNA methylation changes related to grafting may be partly responsible for intraclonal variatio
Externí odkaz:
https://doaj.org/article/42fd556475c64666a441897fb8954dee
Autor:
Stanislav A. Vasilyev, Oksana Yu. Vasilyeva, Bismark Oppong-Peprah, Victoria V. Demeneva, Andrey S. Zuev, Elena A. Sazhenova, Tatiana V. Nikitina, Ekaterina N. Tolmacheva
Publikováno v:
RUDN Journal of Medicine, Vol 27, Iss 4, Pp 515-531 (2023)
Relevance. Abnormal epigenetic regulation of genes responsible for the development of the embryo and placenta is associated with many pregnancy pathologies. Aim. The aim of this work was to analyze the prevalence of abnormal methylation of the PRDM16
Externí odkaz:
https://doaj.org/article/1cd2e0681a16440aaac46dc6989c1e51