Zobrazeno 1 - 10
of 108
pro vyhledávání: '"birgit koch"'
Autor:
Melanie M. Callaghan, Birgit Koch, Kathleen T. Hackett, Amy K. Klimowicz, Ryan E. Schaub, Natalio Krasnogor, Joseph P. Dillard
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Partitioning proteins are well studied as molecular organizers of chromosome and plasmid segregation during division, however little is known about the roles partitioning proteins can play within type IV secretion systems. The single-stranded DNA (ss
Externí odkaz:
https://doaj.org/article/60d01759ed504775911f75ac7417d547
Autor:
Johann Holzmann, Antonio Z Politi, Kota Nagasaka, Merle Hantsche-Grininger, Nike Walther, Birgit Koch, Johannes Fuchs, Gerhard Dürnberger, Wen Tang, Rene Ladurner, Roman R Stocsits, Georg A Busslinger, Béla Novák, Karl Mechtler, Iain Finley Davidson, Jan Ellenberg, Jan-Michael Peters
Publikováno v:
eLife, Vol 8 (2019)
The organisation of mammalian genomes into loops and topologically associating domains (TADs) contributes to chromatin structure, gene expression and recombination. TADs and many loops are formed by cohesin and positioned by CTCF. In proliferating ce
Externí odkaz:
https://doaj.org/article/b4dd695cfba54d39a1aacd86fcfa079a
Publikováno v:
eLife, Vol 7 (2018)
We introduce a new class of semisynthetic fluorescent biosensors for the quantification of free nicotinamide adenine dinucleotide (NAD+) and ratios of reduced to oxidized nicotinamide adenine dinucleotide phosphate (NADPH/NADP+) in live cells. Sensin
Externí odkaz:
https://doaj.org/article/439c6df780ef4aae81c96e9cc3645c73
Autor:
Shotaro Otsuka, Khanh Huy Bui, Martin Schorb, M Julius Hossain, Antonio Z Politi, Birgit Koch, Mikhail Eltsov, Martin Beck, Jan Ellenberg
Publikováno v:
eLife, Vol 5 (2016)
The nuclear pore complex (NPC) mediates nucleocytoplasmic transport through the nuclear envelope. How the NPC assembles into this double membrane boundary has remained enigmatic. Here, we captured temporally staged assembly intermediates by correlati
Externí odkaz:
https://doaj.org/article/e7d3ccf9ec384e3e9334a9fd70344689
Autor:
Erhard van der Vries, Koert J Stittelaar, Geert van Amerongen, Edwin J B Veldhuis Kroeze, Leon de Waal, Pieter L A Fraaij, Roland J Meesters, Theo M Luider, Bart van der Nagel, Birgit Koch, Arnold G Vulto, Martin Schutten, Albert D M E Osterhaus
Publikováno v:
PLoS Pathogens, Vol 9, Iss 5, p e1003343 (2013)
Immunocompromised individuals tend to suffer from influenza longer with more serious complications than otherwise healthy patients. Little is known about the impact of prolonged infection and the efficacy of antiviral therapy in these patients. Among
Externí odkaz:
https://doaj.org/article/bc27865fd6ff43239c72447f6d265e1d
Autor:
Silke Hauf, Elisabeth Roitinger, Birgit Koch, Christina M Dittrich, Karl Mechtler, Jan-Michael Peters
Publikováno v:
PLoS Biology, Vol 3, Iss 3, p e69 (2005)
Cohesin is a protein complex that is required to hold sister chromatids together. Cleavage of the Scc1 subunit of cohesin by the protease separase releases the complex from chromosomes and thereby enables the separation of sister chromatids in anapha
Externí odkaz:
https://doaj.org/article/ef08dfe1f4644307ad2168b024e6e265
Autor:
Shotaro Otsuka, Jeremy O. B. Tempkin, Wanlu Zhang, Antonio Z. Politi, Arina Rybina, M. Julius Hossain, Moritz Kueblbeck, Andrea Callegari, Birgit Koch, Natalia Rosalia Morero, Andrej Sali, Jan Ellenberg
Publikováno v:
Nature
SummaryUnderstanding how the nuclear pore complex (NPC) assembles is of fundamental importance to grasp the mechanisms behind its essential function and understand its role during evolution of eukaryotes1–4. While at least two NPC assembly pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b485869426814ab170e3f293ff44229
https://doi.org/10.1038/s41586-022-05528-w
https://doi.org/10.1038/s41586-022-05528-w
Autor:
Lars Hellweg, Anna Edenhofer, Lucas Barck, Magnus-Carsten Huppertz, Michelle. S. Frei, Miroslaw Tarnawski, Andrea Bergner, Birgit Koch, Kai Johnsson, Julien Hiblot
Publikováno v:
Nature Chemical Biology
Fluorescent biosensors enable to study cell physiology with spatiotemporal resolution, yet most biosensors suffer from relatively low dynamic ranges. Here, we introduce a family of designed Förster Resonance Energy Transfer (FRET) pairs with near qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df482d6728ec3235a1855f3f5433de32
https://doi.org/10.1101/2022.11.29.518186
https://doi.org/10.1101/2022.11.29.518186
Autor:
Jonathan D. G. Jones, Patrick Römer, Stefan Werner, Nicolaus von Wirén, Doreen Bartels, Kostya Kanyuka, Gerd Hause, Birgit Koch, Anka Thümmler, Stefano Torti, Vinay Panwar, René Schlesier, Anatoli Giritch, Yuri Gleba
Publikováno v:
Nature Plants. 7:159-171
The development of a new crop variety is a time-consuming and costly process due to the reliance of plant breeding on gene shuffling to introduce desired genes into elite germplasm, followed by backcrossing. Here, we propose alternative technology th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3789b5e3824ab962887714b800bf5fee
https://doi.org/10.1038/s41477-021-00851-y
https://doi.org/10.1038/s41477-021-00851-y
Autor:
Marvin Busch, Nicole Mertes, Magnus-Carsten Huppertz, Clara-Marie Gürth, Stefanie Kühn, Birgit Koch, Kai Johnsson, Julien Hiblot, Christina Nicole Hacker
Publikováno v:
Journal of the American Chemical Society
We introduce a family of bright, rhodamine-based calcium indicators with tuneable affinities and colors. The indicators can be specifically localized to different cellular compartments and are compatible with both fluorescence and bioluminescence rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf9169461a652b711649ac0912bce6b
https://pubmed.ncbi.nlm.nih.gov/35380808
https://pubmed.ncbi.nlm.nih.gov/35380808