Zobrazeno 1 - 10
of 1 239
pro vyhledávání: '"biotherapeutic"'
Publikováno v:
AAPS Open, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Structured product quality data offer tremendous promise to revolutionize the submission of drug applications. However, the quality attributes for biological products do not have a systematic naming taxonomy, and consequently this limit pose
Externí odkaz:
https://doaj.org/article/72e2a975380d40729bd55916752a1c53
Publikováno v:
Patient Preference and Adherence, Vol Volume 18, Pp 1547-1562 (2024)
Joshua T Myers, Jacques Van Dam, Mir Imran, Mir Hashim, Arvinder K Dhalla Rani Therapeutics, San Jose, CA, USACorrespondence: Joshua T Myers, Rani Therapeutics, 2051 Ringwood Ave, San Jose, CA, 95131, USA, Tel +1 408-457-3700, Email joshua.myers@rani
Externí odkaz:
https://doaj.org/article/01d6125c93064099bb5288df912e236b
Autor:
Jiayuan Huang, Sanxin Liu, Peijie Li, Lei Wei, Gan Lin, Jiahao Lin, Yuting Luo, Yixin Liu, Yudan Mao, Hengfang Ruan, Bing Qin, Ping Fan, Tingting Lu, Wei Cai, Haotong Yi, Xiangyu Mou, Zhengqi Lu, Wenjing Zhao, Aimin Wu
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107385- (2024)
Arteriosclerotic cerebral small vessel disease (aCSVD) is a major cause of stroke and dementia. Although its underlying pathogenesis remains poorly understood, both inflammaging and gut microbiota dysbiosis have been hypothesized to play significant
Externí odkaz:
https://doaj.org/article/0643464ede9e48ada920811d53b1500f
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Cancer is a leading cause of mortality globally, often diagnosed at advanced stages with metastases already present, complicating treatment efficacy. Traditional treatments like chemotherapy and radiotherapy face challenges such as lack of specificit
Externí odkaz:
https://doaj.org/article/cc13b65a926a4caa85e972e1454ebcb1
Autor:
Bhagyashri D. Navalkele, Teena Chopra
Publikováno v:
Frontiers in Microbiomes, Vol 3 (2024)
Live biotherapeutics products (LBP) are a novel range of therapeutic options in medicine. In this review, authors discuss basic composition and mechanism of action of LBP, provide a comprehensive focused overview of published in vitro and in vivo stu
Externí odkaz:
https://doaj.org/article/01da2a594426460ba1900e805676e4fd
Autor:
Jason Goldsmith, Sarah Tomkovich, John G. Auniņš, Barbara H. McGovern, Jennifer C. Mahoney, Brooke R. Hasson, Christopher W J McChalicher, David S. Ege
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Advances in microbiome therapeutics have been motivated by a deeper understanding of the role that the gastrointestinal microbiome plays in human health and disease. The FDA approval of two stool-derived live biotherapeutic products (LBPs), REBYOTA®
Externí odkaz:
https://doaj.org/article/d50c2aaf0d6047ffbd335412cd5b848c
Autor:
Abigail L. Reens, Casey M. Cosetta, Russell Saur, Olivia Trofimuk, Sarah L. Brooker, Martin L. Lee, Adam K. Sun, Gregory J. McKenzie, Julie E. Button
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTPrecision engineering of the gut microbiome holds promise as an effective therapeutic approach for diseases associated with a disruption in this microbial community. Engrafting a live biotherapeutic product (LBP) in a predictable, controllabl
Externí odkaz:
https://doaj.org/article/d8ad5f1a61ed40549147fcb07f5440db
Publikováno v:
Frontiers in Microbiomes, Vol 3 (2024)
The recent FDA approvals of Rebyota™ and Vowst™ represent landmark milestones within the burgeoning field of live microbiota-based products. Future microbiota-based treatment approaches also hold significant promise for treating patients with a m
Externí odkaz:
https://doaj.org/article/218c2837c9674db7af6e92283bb20be2
Autor:
Isabel Tarrant, B. Brett Finlay
Publikováno v:
Frontiers in Microbiomes, Vol 3 (2024)
With the global prevalence of allergic disease continuing to rise at an alarming rate, the need for effective and safe therapeutics is paramount. Given the critical role of the early-life microbiota on immune development, emerging research suggests t
Externí odkaz:
https://doaj.org/article/39aa3fc314fa40b49251cf633d089d41
Autor:
Robert J. Dorosky, Jeremy E. Schreier, Stephanie L. Lola, Rosa L. Sava, Michael P. Coryell, Adovi Akue, Mark KuKuruga, Paul E. Carlson, Sheila M. Dreher-Lesnick, Scott Stibitz
Publikováno v:
AMB Express, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Nanobodies are highly specific binding domains derived from naturally occurring single chain camelid antibodies. Live biotherapeutic products (LBPs) are biological products containing preparations of live organisms, such as Lactobacillus, th
Externí odkaz:
https://doaj.org/article/7cd372ca8a2e40b3a7ac94c9591b6358