Zobrazeno 1 - 5
of 5
pro vyhledávání: '"biosynthesis [Transcription Factors]"'
Autor:
Klaus Fliessbach, Oliver Brüstle, Catrin Cornelia Thiele, Monika Veltel, Michael Peitz, Alfredo Ramirez, Melanie Bloschies, Tamara Bechler
Publikováno v:
Stem Cell Research, Vol 29, Iss, Pp 250-253 (2018)
Stem Cell Research
Stem cell research 29, 250-253 (2018). doi:10.1016/j.scr.2018.04.011
Stem Cell Research
Stem cell research 29, 250-253 (2018). doi:10.1016/j.scr.2018.04.011
Alzheimer's disease (AD) is most the frequent neurodegenerative disease, and the APOE ε4 allele is the most prominent risk factor for late-onset AD. Here, we present an iPSC line generated from peripheral blood cells of a male AD patient employing S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346c0978d49054a6e1b3a655e169bee2
https://zenodo.org/record/2543236
https://zenodo.org/record/2543236
Autor:
Hans Werner Müller, Frank Bradke, Malleswari Challagundla, Thomas Ostendorf, Uwe Michel, Vinicius Toledo Ribas, Mathias Bähr, Sebastian Kügler, Paul Lingor, Jan C. Koch
Publikováno v:
Journal of neurochemistry 134(2), 261-275 (2015). doi:10.1111/jnc.13102
A lesion to the rat rubrospinal tract is a model for traumatic spinal cord lesions and results in atrophy of the red nucleus neurons, axonal dieback, and locomotor deficits. In this study, we used adeno-associated virus (AAV)-mediated over-expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038478c060c4e44279d8cab4853f6575
https://doi.org/10.1111/jnc.13102
https://doi.org/10.1111/jnc.13102
Autor:
Frank Edenhofer, Dominic Seiferling, Marc Thier, Tamara Quandel, Per Hoffmann, Oliver Brüstle, Raphaela Gorris, Markus M. Nöthen, Thoralf Opitz, Yenal Bernard Lakes, Stefan Herms, Philipp Wörsdörfer
Publikováno v:
Cell Stem Cell
Cell Stem Cell; Vol 10
Cell stem cell 10(4), 473-479 (2012). doi:10.1016/j.stem.2012.03.003
Cell Stem Cell; Vol 10
Cell stem cell 10(4), 473-479 (2012). doi:10.1016/j.stem.2012.03.003
SummaryRecent advances have suggested that direct induction of neural stem cells (NSCs) could provide an alternative to derivation from somatic tissues or pluripotent cells. Here we show direct derivation of stably expandable NSCs from mouse fibrobla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d2b141e66e647aa036454ef759385d
Autor:
Köhler, Andrea, Demir, Ümmühan, Kickstein, Eva, Krauss, Sybille, Aigner, Johanna, Aranda-Orgillés, Beatriz, Karagiannidis, Antonios I, Achmüller, Clemens, Bu, Huajie, Wunderlich, Andrea, Schweiger, Michal-Ruth, Schaefer, Georg, Schweiger, Susann, Klocker, Helmut, Schneider, Rainer
Publikováno v:
Molecular cancer 13(1), 146 (2014). doi:10.1186/1476-4598-13-146
Molecular Cancer
Molecular Cancer
Background High androgen receptor (AR) level in primary tumour predicts increased prostate cancer (PCa)-specific mortality. Furthermore, activations of the AR, PI3K, mTOR, NFκB and Hedgehog (Hh) signaling pathways are involved in the fatal developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e52f8beb3e766476ec9eee333d6a844a
https://pub.dzne.de/record/141353
https://pub.dzne.de/record/141353
Autor:
Hoon Taek Lee, Ji Hun Yang, Andreas Hermann, Guangming Wu, Kathrin Hemmer, Boris Greber, Hans R. Schöler, Jens Christian Schwamborn, Alexander Storch, Dong Wook Han, Stefan Frank, Holm Zaehres, Natalia Tapia, Marcos J. Araúzo-Bravo, Sören Moritz, Susanne Höing
Publikováno v:
Cell stem cell 10(4), 465-472 (2012). doi:10.1016/j.stem.2012.02.021
Summary Recent studies have shown that defined sets of transcription factors can directly reprogram differentiated somatic cells to a different differentiated cell type without passing through a pluripotent state, but the restricted proliferative and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf5f16593640d3934d76dab41918a3b
https://pub.dzne.de/record/136492
https://pub.dzne.de/record/136492